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The current landscape of m6A modification in urological cancers.
Zeng, Yaohui; Lv, Cai; Wan, Bangbei; Gong, Binghao.
Afiliación
  • Zeng Y; Department of Urology, Central South University Xiangya School of Medicine Affiliated Haikou Hospital, Haikou, China.
  • Lv C; Department of Urology, Central South University Xiangya School of Medicine Affiliated Haikou Hospital, Haikou, China.
  • Wan B; Department of Urology, Central South University Xiangya School of Medicine Affiliated Haikou Hospital, Haikou, China.
  • Gong B; Department of Urology, Central South University Xiangya School of Medicine Affiliated Haikou Hospital, Haikou, China.
PeerJ ; 11: e16023, 2023.
Article en En | MEDLINE | ID: mdl-37701836
N6-methyladenosine (m6A) methylation is a dynamic and reversible procession of epigenetic modifications. It is increasingly recognized that m6A modification has been involved in the tumorigenesis, development, and progression of urological tumors. Emerging research explored the role of m6A modification in urological cancer. In this review, we will summarize the relationship between m6A modification, renal cell carcinoma, bladder cancer, and prostate cancer, and discover the biological function of m6A regulators in tumor cells. We will also discuss the possible mechanism and future application value used as a potential biomarker or therapeutic target to benefit patients with urological cancers.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Neoplasias de la Vejiga Urinaria / Neoplasias Urológicas / Neoplasias Renales Límite: Humans / Male Idioma: En Revista: PeerJ Año: 2023 Tipo del documento: Article País de afiliación: China

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Neoplasias de la Vejiga Urinaria / Neoplasias Urológicas / Neoplasias Renales Límite: Humans / Male Idioma: En Revista: PeerJ Año: 2023 Tipo del documento: Article País de afiliación: China