Targeted transcriptional upregulation of SENP1 by CRISPR activation enhances deSUMOylation pathways to elicit antinociception in the spinal nerve ligation model of neuropathic pain.

Gomez, Kimberly; Allen, Heather N; Duran, Paz; Loya-Lopez, Santiago; Calderon-Rivera, Aida; Moutal, Aubin; Tang, Cheng; Nelson, Tyler S; Perez-Miller, Samantha; Khanna, Rajesh

Gomez, Kimberly; Allen, Heather N; Duran, Paz; Loya-Lopez, Santiago; Calderon-Rivera, Aida; Moutal, Aubin; Tang, Cheng; Nelson, Tyler S; Perez-Miller, Samantha; Khanna, Rajesh.

Afiliación

Gomez K; Department of Molecular Pathobiology, College of Dentistry, New York University, New York, NY, United States.
Allen HN; NYU Pain Research Center, New York, NY, United States.
Duran P; Department of Molecular Pathobiology, College of Dentistry, New York University, New York, NY, United States.
Loya-Lopez S; NYU Pain Research Center, New York, NY, United States.
Calderon-Rivera A; Department of Molecular Pathobiology, College of Dentistry, New York University, New York, NY, United States.
Moutal A; NYU Pain Research Center, New York, NY, United States.
Tang C; Department of Molecular Pathobiology, College of Dentistry, New York University, New York, NY, United States.
Nelson TS; NYU Pain Research Center, New York, NY, United States.
Perez-Miller S; Department of Molecular Pathobiology, College of Dentistry, New York University, New York, NY, United States.
Khanna R; NYU Pain Research Center, New York, NY, United States.

Pain ; 165(4): 866-883, 2024 Apr 01.

Article en En | MEDLINE | ID: mdl-37862053

Asunto(s)

Hiperalgesia; Neuralgia; Ratas; Masculino; Femenino; Humanos; Animales; Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas; Regulación hacia Arriba; Ratas Sprague-Dawley; Neuralgia/genética; Nervios Espinales; Ganglios Espinales; Cisteína Endopeptidasas/genética

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Hiperalgesia / Neuralgia Límite: Animals / Female / Humans / Male Idioma: En Revista: Pain Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos

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