Pathogenicity of functionally activated PD-1<sup>+</sup>CD8<sup>+</sup> cells and counterattacks by muscular PD-L1 through IFNÎ³ in myositis.

Sasaki, Hirokazu; Umezawa, Natsuka; Itakura, Takuji; Iwai, Hideyuki; Yasuda, Shinsuke

Pathogenicity of functionally activated PD-1⁺CD8⁺ cells and counterattacks by muscular PD-L1 through IFNÎ³ in myositis.

Sasaki, Hirokazu; Umezawa, Natsuka; Itakura, Takuji; Iwai, Hideyuki; Yasuda, Shinsuke.

Afiliación

Sasaki H; Department of Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
Umezawa N; Department of Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
Itakura T; Department of Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
Iwai H; Department of Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
Yasuda S; Department of Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan. Electronic address: syasuda.rheu@tmd.ac.jp.

J Autoimmun ; 142: 103131, 2024 Jan.

Article en En | MEDLINE | ID: mdl-37931332

Asunto(s)

Linfocitos T CD8-positivos; Polimiositis; Humanos; Animales; Ratones; Receptor de Muerte Celular Programada 1/metabolismo; Antígeno B7-H1/metabolismo; Virulencia

Palabras clave

IFNÎ³; Idiopathic inflammatory myopathies; Programmed-cell-death 1 (PD-1); Programmed-cell-death 1 ligand 1 (PD-L1); T cell exhaustion

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Polimiositis / Linfocitos T CD8-positivos Límite: Animals / Humans Idioma: En Revista: J Autoimmun Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Japón

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