Development and Pilot of an Mpox Severity Scoring System.
J Infect Dis
; 229(Supplement_2): S229-S233, 2024 Mar 26.
Article
en En
| MEDLINE
| ID: mdl-37956401
ABSTRACT
Clinical severity scores facilitate comparisons to understand risk factors for severe illness. For the 2022 multinational monkeypox clade IIb virus outbreak, we developed a 7-item Mpox Severity Scoring System (MPOX-SSS) with initial variables refined by data availability and parameter correlation. Application of MPOX-SSS to the first 200 patients diagnosed with mpox revealed higher scores in those treated with tecovirimat, presenting >3 days after symptom onset, and with CD4 counts <200â
cells/mm3. For individuals evaluated repeatedly, serial scores were concordant with clinical observations. The pilot MPOX-SSS demonstrated good discrimination, distinguished change over time, and identified higher scores in expected groups.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Mpox
Límite:
Humans
Idioma:
En
Revista:
J Infect Dis
Año:
2024
Tipo del documento:
Article