Transmembrane Helices 7 and 8 Confer Aggregation Sensitivity to the Cystic Fibrosis Transmembrane Conductance Regulator.

Kleizen, Bertrand; de Mattos, Eduardo; Papaioannou, Olga; Monti, Michele; Tartaglia, Gian Gaetano; van der Sluijs, Peter; Braakman, Ineke

Kleizen, Bertrand; de Mattos, Eduardo; Papaioannou, Olga; Monti, Michele; Tartaglia, Gian Gaetano; van der Sluijs, Peter; Braakman, Ineke.

Afiliación

Kleizen B; Cellular Protein Chemistry, Bijvoet Centre for Biomolecular Research, Utrecht University, 3584 CH Utrecht, The Netherlands.
de Mattos E; Cellular Protein Chemistry, Bijvoet Centre for Biomolecular Research, Utrecht University, 3584 CH Utrecht, The Netherlands.
Papaioannou O; Cellular Protein Chemistry, Bijvoet Centre for Biomolecular Research, Utrecht University, 3584 CH Utrecht, The Netherlands.
Monti M; Center for Life Nano- & Neuro-Science, Fondazione Istituto Italiano di Tecnologia (IIT), 00161 Rome, Italy.
Tartaglia GG; Centre for Human Technologies (CHT), Istituto Italiano di Tecnologia (IIT), 16152 Genoa, Italy.
van der Sluijs P; Center for Life Nano- & Neuro-Science, Fondazione Istituto Italiano di Tecnologia (IIT), 00161 Rome, Italy.
Braakman I; Centre for Human Technologies (CHT), Istituto Italiano di Tecnologia (IIT), 16152 Genoa, Italy.

Int J Mol Sci ; 24(21)2023 Oct 30.

Article en En | MEDLINE | ID: mdl-37958724

Asunto(s)

Regulador de Conductancia de Transmembrana de Fibrosis Quística; Calor; Regulador de Conductancia de Transmembrana de Fibrosis Quística/metabolismo; Membrana Celular/metabolismo; Proteolisis; Temperatura

Palabras clave

CFTR; TM7; TM8; TMD2; aggregation; instability; thermal sensitivity

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Regulador de Conductancia de Transmembrana de Fibrosis Quística / Calor Idioma: En Revista: Int J Mol Sci Año: 2023 Tipo del documento: Article País de afiliación: Países Bajos

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