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Sleep restoration by optogenetic targeting of GABAergic neurons reprograms microglia and ameliorates pathological phenotypes in an Alzheimer's disease model.
Zhao, Qiuchen; Maci, Megi; Miller, Morgan R; Zhou, Heng; Zhang, Fang; Algamal, Moustafa; Lee, Yee Fun; Hou, Steven S; Perle, Stephen J; Le, Hoang; Russ, Alyssa N; Lo, Eng H; Gerashchenko, Dmitry; Gomperts, Stephen N; Bacskai, Brian J; Kastanenka, Ksenia V.
Afiliación
  • Zhao Q; Department of Neurology, MassGeneral Institute of Neurodegenerative Diseases, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA.
  • Maci M; Department of Neurology, MassGeneral Institute of Neurodegenerative Diseases, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA.
  • Miller MR; Department of Neurology, MassGeneral Institute of Neurodegenerative Diseases, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA.
  • Zhou H; Department of Neurology, MassGeneral Institute of Neurodegenerative Diseases, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA.
  • Zhang F; Departments of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA.
  • Algamal M; Department of Neurology, MassGeneral Institute of Neurodegenerative Diseases, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA.
  • Lee YF; Department of Neurology, MassGeneral Institute of Neurodegenerative Diseases, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA.
  • Hou SS; Department of Neurology, MassGeneral Institute of Neurodegenerative Diseases, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA.
  • Perle SJ; Department of Neurology, MassGeneral Institute of Neurodegenerative Diseases, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA.
  • Le H; Department of Neurology, MassGeneral Institute of Neurodegenerative Diseases, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA.
  • Russ AN; Department of Neurology, MassGeneral Institute of Neurodegenerative Diseases, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA.
  • Lo EH; Departments of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA.
  • Gerashchenko D; Department of Psychiatry, Harvard Medical School and Veterans Affairs Boston Healthcare System, West Roxbury, MA, 02132, USA.
  • Gomperts SN; Department of Neurology, MassGeneral Institute of Neurodegenerative Diseases, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA.
  • Bacskai BJ; Department of Neurology, MassGeneral Institute of Neurodegenerative Diseases, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA.
  • Kastanenka KV; Department of Neurology, MassGeneral Institute of Neurodegenerative Diseases, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA. KKASTANENKA@mgh.harvard.edu.
Mol Neurodegener ; 18(1): 93, 2023 Dec 01.
Article en En | MEDLINE | ID: mdl-38041158
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedad de Alzheimer Límite: Animals / Humans Idioma: En Revista: Mol Neurodegener Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedad de Alzheimer Límite: Animals / Humans Idioma: En Revista: Mol Neurodegener Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos