Neurogastroenterology and Motility Disorders of the Gastrointestinal Tract in Cystic Fibrosis.
Curr Gastroenterol Rep
; 26(1): 9-19, 2024 Jan.
Article
en En
| MEDLINE
| ID: mdl-38057499
PURPOSE OF REVIEW: To discuss all the various motility disorders impacting people with Cystic Fibrosis (PwCF) and provide diagnostic and management approaches from a group of pediatric and adult CF and motility experts and physiologists with experience in the management of this disease. RECENT FINDINGS: Gastrointestinal (GI) symptoms coexist with pulmonary symptoms in PwCF regardless of age and sex. The GI manifestations include gastroesophageal reflux disease, esophageal dysmotility gastroparesis, small bowel dysmotility, small intestinal bacterial overgrowth syndrome, distal idiopathic obstruction syndrome, constipation, and pelvic floor disorders. They are quite debilitating, limiting the patients' quality of life and affecting their nutrition and ability to socialize. This genetic disorder affects many organ systems and is chronic, potentially impacting fertility and future family planning, requiring a multidisciplinary approach. Our review discusses the treatments of motility disorders in CF, their prevalence and pathophysiology. We have provided a framework for clinicians who care for these patients that can help to guide their clinical management.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Reflujo Gastroesofágico
/
Fibrosis Quística
/
Enfermedades Gastrointestinales
Límite:
Adult
/
Child
/
Humans
Idioma:
En
Revista:
Curr Gastroenterol Rep
Asunto de la revista:
GASTROENTEROLOGIA
Año:
2024
Tipo del documento:
Article
País de afiliación:
Estados Unidos