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3,3',5,5'-Tetramethoxybiphenyl-4,4'diol triggers oxidative stress, metabolic changes, and apoptosis-like process by reducing the PI3K/AKT/NF-κB pathway in the NCI-H460 lung cancer cell line.
Concato-Lopes, Virginia Marcia; Silva, Taylon Felipe; Detoni, Mariana Barbosa; Cruz, Ellen Mayara Souza; Gonçalves, Manoela Daiele; da Silva Bortoleti, Bruna Taciane; Tomiotto-Pellissier, Fernanda; Carloto, Amanda Cristina Machado; Madureira, Maria Beatriz; Rodrigues, Ana Carolina Jacob; Schirmann, Jéseka Gabriela; Barbosa-Dekker, Aneli M; Dekker, Robert F H; Conchon-Costa, Ivete; Panis, Carolina; Lazarin-Bidóia, Danielle; Miranda-Sapla, Milena Menegazzo; Mantovani, Mário Sérgio; Pavanelli, Wander R.
Afiliación
  • Concato-Lopes VM; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil. Electronic address: vir_93_@hotmail.com.
  • Silva TF; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil.
  • Detoni MB; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil.
  • Cruz EMS; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil.
  • Gonçalves MD; Laboratory of Biotransformation and Phytochemical, Department of Chemistry, Center of Exact Sciences, State University of Londrina, PR, Brazil.
  • da Silva Bortoleti BT; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil; Graduate Program in Biosciences and Biotechnology, Carlos Chagas Institute (ICC), Fiocruz, Curitib
  • Tomiotto-Pellissier F; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil; Graduate Program in Biosciences and Biotechnology, Carlos Chagas Institute (ICC), Fiocruz, Curitib
  • Carloto ACM; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil.
  • Madureira MB; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil.
  • Rodrigues ACJ; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil; Graduate Program in Biosciences and Biotechnology, Carlos Chagas Institute (ICC), Fiocruz, Curitib
  • Schirmann JG; Laboratory Research of Bioactive Molecules, Department of Chemistry, Center of Exact Sciences, State University of Londrina, PR, Brazil.
  • Barbosa-Dekker AM; Laboratory Research of Bioactive Molecules, Department of Chemistry, Center of Exact Sciences, State University of Londrina, PR, Brazil.
  • Dekker RFH; Federal Technological University of Paraná, Graduate Program in Environmental Engineering, Campus Londrina, Londrina, PR, Brazil.
  • Conchon-Costa I; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil.
  • Panis C; Laboratory of Tumor Biology, State University of West Paraná, Unioeste, Francisco Beltrao, Brazil.
  • Lazarin-Bidóia D; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil.
  • Miranda-Sapla MM; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil.
  • Mantovani MS; Laboratory of Toxicological Genetics, Department of General Biology, Center of Biological Sciences, State University of Londrina, PR, Brazil.
  • Pavanelli WR; Laboratory of Immunoparasitology of Neglected Diseases and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, State University of Londrina, PR, Brazil.
Biomed Pharmacother ; 170: 115979, 2024 Jan.
Article en En | MEDLINE | ID: mdl-38061138
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Pulmonares / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Revista: Biomed Pharmacother Año: 2024 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Pulmonares / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Revista: Biomed Pharmacother Año: 2024 Tipo del documento: Article