Effects of mitral valve repair on valvular geometry and hemodynamics in dogs with myxomatous mitral valve disease.
Vet Surg
; 53(3): 415-425, 2024 Apr.
Article
en En
| MEDLINE
| ID: mdl-38205863
ABSTRACT
OBJECTIVE:
To investigate the effects of mitral valve repair on the geometry of the mitral valve complex, hemodynamics, and cardiac function of dogs with myxomatous mitral valve disease (MMVD). STUDYDESIGN:
Retrospective cohort study. SAMPLE POPULATION Dogs (n = 77) with stage C MMVD undergoing mitral valve repair under cardiopulmonary bypass.METHODS:
Mitral valve geometry and cardiac function were assessed using echocardiography preoperatively, 1 week postoperatively and 3 months postoperatively.RESULTS:
The coaptation length (0 [0-0] vs. 7 [6-8.5] mm, p < .001) and forward stroke volume index (1.5 ± 0.4 vs. 2.3 ± 0.6 mL/kg, p < .001) were higher at 3-months postoperatively than preoperatively, whereas the vertebral heart score (12.3 ± 1.2 vs. 10.8 ± 0.8 V, p < .001), left atrial-to-aortic ratio (2.2 ± 0.7 vs. 1.2 ± 0.3, p < .001), peak velocity of early diastolic transmitral flow (144 ± 34 vs. 91 ± 18 cm/s, p < .001), and regurgitant volume index (11.3 [8.2-14.0] vs. 1.6 [0.95-2.35] mL/kg, p < .001) were lower. Postoperatively, mitral valve geometry was completely changed within 1 week, whereas changes in vertebral heart score lasted for 3 months.CONCLUSION:
Mitral valve repair changed valvular geometry and improved hemodynamics as assessed by follow-up echocardiography. CLINICALSIGNIFICANCE:
This study acts as reference for surgeons and cardiologists considering or evaluating the effects of mitral valve repair in dogs and provides useful data for the enhancement of relevant surgical techniques and the selection of relevant pre- and postoperative observations.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Enfermedades de los Perros
/
Válvula Mitral
Tipo de estudio:
Observational_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Vet Surg
Año:
2024
Tipo del documento:
Article
País de afiliación:
Japón