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Oxidative cascade cyclization of N-arylacrylamides with TMSN3.
Jiang, Bo; Fan, Tai-Gang; Ran, Yu-Song; Shen, Yun-Tao; Zhang, Cui; Jiang, Wei; Li, Ya-Min.
Afiliación
  • Jiang B; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, P. R. China. liym@kust.edu.cn.
  • Fan TG; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, P. R. China. liym@kust.edu.cn.
  • Ran YS; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, P. R. China. liym@kust.edu.cn.
  • Shen YT; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, P. R. China. liym@kust.edu.cn.
  • Zhang C; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, P. R. China. liym@kust.edu.cn.
  • Jiang W; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, P. R. China. liym@kust.edu.cn.
  • Li YM; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, P. R. China. liym@kust.edu.cn.
Org Biomol Chem ; 22(6): 1186-1193, 2024 Feb 07.
Article en En | MEDLINE | ID: mdl-38214570
ABSTRACT
An azido-radical-triggered cyclization of N-(o-cyanobiaryl)acrylamides with TMSN3via a C(sp3)-N/C(sp2)-C(sp3)/C(sp2)-N bond formation cascade is described. This reaction features mild conditions and high bond-forming efficiency, making it an efficient method for the construction of azide-substituted pyridophenanthridines.

Texto completo: 1 Banco de datos: MEDLINE Idioma: En Revista: Org Biomol Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2024 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Idioma: En Revista: Org Biomol Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2024 Tipo del documento: Article