The Importance of Spin-Polarized Charge Reorganization in the Catalytic Activity of D-Glucose Oxidase.
Chemphyschem
; 25(10): e202400033, 2024 May 17.
Article
en En
| MEDLINE
| ID: mdl-38411033
ABSTRACT
The reaction of D-glucose oxidase (GOx) with D- and L-glucose was investigated using confocal fluorescence microscopy and Hall voltage measurements, after the enzyme was adsorbed as a monolayer. By adsorbing the enzyme on a ferromagnetic substrate, we verified that the reaction is spin dependent. This conclusion was supported by monitoring the reaction when the enzyme is adsorbed on a Hall device that does not contain any magnetic elements. The spin dependence is consistent with the chiral-induced spin selectivity (CISS) effect; it can be explained by the improved fidelity of the electron transfer process through the chiral enzyme due to the coupling of the linear momentum of the electrons and their spin. Since the reaction studied often serve as a model system for enzymatic activity, the results may suggest the general importance of the spin-dependent electron transfer in bio-chemical processes.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Glucosa
/
Glucosa Oxidasa
Idioma:
En
Revista:
Chemphyschem
Asunto de la revista:
BIOFISICA
/
QUIMICA
Año:
2024
Tipo del documento:
Article
País de afiliación:
Israel