Predicting plasma cell retention and loss over a lifetime.
Immunity
; 57(3): 408-410, 2024 Mar 12.
Article
en En
| MEDLINE
| ID: mdl-38479357
ABSTRACT
Plasma cells (PCs) rely on external survival cues for persistence, which limits the size of the PC pool. How, then, are new specificities incorporated into a saturated system? In this issue of Immunity, Simons and Karin put forward a mathematical framework to explain PC retention that makes testable predictions about steady-state lifespan structure, withstands tests based on accrual and displaceability, and accounts for lifespan stratification with specificity.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Células Plasmáticas
Idioma:
En
Revista:
Immunity
Asunto de la revista:
ALERGIA E IMUNOLOGIA
Año:
2024
Tipo del documento:
Article
País de afiliación:
Australia