Oxalate nephropathy after pancreaticoduodenectomy: a case report.
BMC Nephrol
; 25(1): 106, 2024 Mar 18.
Article
en En
| MEDLINE
| ID: mdl-38500054
ABSTRACT
A 75-year-old male developed acute kidney injury KDIGO stage 3 a few weeks after Whipple surgery was performed for a distal cholangiocarcinoma. Kidney biopsy revealed oxalate nephropathy. This was attributed to post-Whipple malabsorption, poor compliance with pancreatic enzyme replacement therapy, and daily intake of vitamin C supplements. Pancreatic enzyme replacement therapy was resumed and calcium carbonate initiated, with an improvement in glomerular filtration rate. Unfortunately, due to oncological progression, best supportive care was initiated.We review the pathophysiology and conditions predisposing to secondary hyperoxaluria and oxalate nephropathy. This diagnosis should be considered among the main causes of acute kidney injury following pancreatectomy, with important therapeutic implications.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Hiperoxaluria
/
Lesión Renal Aguda
Límite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
BMC Nephrol
Asunto de la revista:
NEFROLOGIA
Año:
2024
Tipo del documento:
Article
País de afiliación:
Bélgica