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Innovative analytical methodologies for characterizing chemical exposure with a view to next-generation risk assessment.
Tkalec, Ziga; Antignac, Jean-Philippe; Bandow, Nicole; Béen, Frederic M; Belova, Lidia; Bessems, Jos; Le Bizec, Bruno; Brack, Werner; Cano-Sancho, German; Chaker, Jade; Covaci, Adrian; Creusot, Nicolas; David, Arthur; Debrauwer, Laurent; Dervilly, Gaud; Duca, Radu Corneliu; Fessard, Valérie; Grimalt, Joan O; Guerin, Thierry; Habchi, Baninia; Hecht, Helge; Hollender, Juliane; Jamin, Emilien L; Klánová, Jana; Kosjek, Tina; Krauss, Martin; Lamoree, Marja; Lavison-Bompard, Gwenaelle; Meijer, Jeroen; Moeller, Ruth; Mol, Hans; Mompelat, Sophie; Van Nieuwenhuyse, An; Oberacher, Herbert; Parinet, Julien; Van Poucke, Christof; Roskar, Robert; Togola, Anne; Trontelj, Jurij; Price, Elliott J.
Afiliación
  • Tkalec Z; RECETOX, Faculty of Science, Masaryk University, Kotlarska 2, Brno, Czech Republic; Jozef Stefan Institute, Department of Environmental Sciences, Ljubljana, Slovenia. Electronic address: ziga.tkalec@recetox.muni.cz.
  • Antignac JP; Oniris, INRAE, LABERCA, 44300 Nantes, France. Electronic address: jean-philippe.antignac@oniris-nantes.fr.
  • Bandow N; German Environment Agency, Laboratory for Water Analysis, Colditzstraße 34, 12099 Berlin, Germany. Electronic address: nicole.bandow@uba.de.
  • Béen FM; Vrije Universiteit Amsterdam, Amsterdam Institute for Life and Environment (A-LIFE), Section Chemistry for Environment and Health, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands; KWR Water Research Institute, Nieuwegein, The Netherlands. Electronic address: f.m.been@vu.nl.
  • Belova L; Toxicological Center, University of Antwerp, 2610 Wilrijk, Belgium. Electronic address: lidia.belova@uantwerpen.be.
  • Bessems J; Flemish Institute for Technological Research (VITO), Mol, Belgium. Electronic address: jos.bessems@vito.be.
  • Le Bizec B; Oniris, INRAE, LABERCA, 44300 Nantes, France. Electronic address: bruno.lebizec@oniris-nantes.fr.
  • Brack W; Helmholtz Centre for Environmental Research GmbH - UFZ, Department of Effect-Directed Analysis, Permoserstraße 15, 04318 Leipzig, Germany; Goethe University Frankfurt, Department of Evolutionary Ecology and Environmental Toxicology, Max-von-Laue-Strasse 13, 60438 Frankfurt, Germany. Electronic addre
  • Cano-Sancho G; Oniris, INRAE, LABERCA, 44300 Nantes, France. Electronic address: german.cano-sancho@oniris-nantes.fr.
  • Chaker J; Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Rennes, France. Electronic address: jade.chaker@ehesp.fr.
  • Covaci A; Toxicological Center, University of Antwerp, 2610 Wilrijk, Belgium. Electronic address: adrian.covaci@uantwerpen.be.
  • Creusot N; INRAE, French National Research Institute For Agriculture, Food & Environment, UR1454 EABX, Bordeaux Metabolome, MetaboHub, Gazinet Cestas, France. Electronic address: nicolas.creusot@inrae.fr.
  • David A; Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Rennes, France. Electronic address: arthur.david@ehesp.fr.
  • Debrauwer L; Toxalim (Research Centre in Food Toxicology), INRAE UMR 1331, ENVT, INP-Purpan, Paul Sabatier University (UPS), Toulouse, France. Electronic address: laurent.debrauwer@inrae.fr.
  • Dervilly G; Oniris, INRAE, LABERCA, 44300 Nantes, France. Electronic address: gaud.dervilly@oniris-nantes.fr.
  • Duca RC; Unit Environmental Hygiene and Human Biological Monitoring, Department of Health Protection, Laboratoire National de Santé (LNS), 1 Rue Louis Rech, L-3555 Dudelange, Luxembourg; Environment and Health, Department of Public Health and Primary Care, Katholieke Universiteit of Leuven (KU Leuven), 3000
  • Fessard V; ANSES, French Agency for Food, Environmental and Occupational Health & Safety, Laboratory of Fougères, Toxicology of Contaminants Unit, 35306 Fougères, France. Electronic address: valerie.fessard@anses.fr.
  • Grimalt JO; Institute of Environmental Assessment and Water Research (IDAEA-CSIC), Barcelona, Catalonia, Spain. Electronic address: joan.grimalt@idaea.csic.es.
  • Guerin T; ANSES, French Agency for Food, Environmental and Occupational Health & Safety, Strategy and Programs Department, F-94701 Maisons-Alfort, France. Electronic address: thierry.guerin@anses.fr.
  • Habchi B; INRS, Département Toxicologie et Biométrologie Laboratoire Biométrologie 1, rue du Morvan - CS 60027 - 54519, Vandoeuvre Cedex, France. Electronic address: baninia.habchi@inrs.fr.
  • Hecht H; RECETOX, Faculty of Science, Masaryk University, Kotlarska 2, Brno, Czech Republic. Electronic address: helge.hecht@recetox.muni.cz.
  • Hollender J; Swiss Federal Institute of Aquatic Science and Technology - Eawag, 8600 Dübendorf, Switzerland; Institute of Biogeochemistry and Pollutant Dynamics, ETH Zürich, 8092 Zürich, Switzerland. Electronic address: juliane.hollender@eawag.ch.
  • Jamin EL; Toxalim (Research Centre in Food Toxicology), INRAE UMR 1331, ENVT, INP-Purpan, Paul Sabatier University (UPS), Toulouse, France. Electronic address: emilien.jamin@inrae.fr.
  • Klánová J; RECETOX, Faculty of Science, Masaryk University, Kotlarska 2, Brno, Czech Republic. Electronic address: jana.klanova@recetox.muni.cz.
  • Kosjek T; Jozef Stefan Institute, Department of Environmental Sciences, Ljubljana, Slovenia. Electronic address: tina.kosjek@ijs.si.
  • Krauss M; Helmholtz Centre for Environmental Research GmbH - UFZ, Department of Effect-Directed Analysis, Permoserstraße 15, 04318 Leipzig, Germany. Electronic address: martin.krauss@ufz.de.
  • Lamoree M; Vrije Universiteit Amsterdam, Amsterdam Institute for Life and Environment (A-LIFE), Section Chemistry for Environment and Health, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands. Electronic address: marja.lamoree@vu.nl.
  • Lavison-Bompard G; ANSES, French Agency for Food, Environmental and Occupational Health & Safety, Laboratory for Food Safety, Pesticides and Marine Biotoxins Unit, F-94701 Maisons-Alfort, France. Electronic address: gwenaelle.lavison-bompard@anses.fr.
  • Meijer J; Vrije Universiteit Amsterdam, Amsterdam Institute for Life and Environment (A-LIFE), Section Chemistry for Environment and Health, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands. Electronic address: j.meijer@vu.nl.
  • Moeller R; Unit Medical Expertise and Data Intelligence, Department of Health Protection, Laboratoire National de Santé (LNS), 1 Rue Louis Rech, L-3555 Dudelange, Luxembourg. Electronic address: Ruth.Moeller@lns.etat.lu.
  • Mol H; Wageningen Food Safety Research - Part of Wageningen University and Research, Akkermaalsbos 2, 6708 WB, Wageningen, The Netherlands. Electronic address: hans.mol@wur.nl.
  • Mompelat S; ANSES, French Agency for Food, Environmental and Occupational Health & Safety, Laboratory of Fougères, Toxicology of Contaminants Unit, 35306 Fougères, France. Electronic address: sophie.mompelat@anses.fr.
  • Van Nieuwenhuyse A; Environment and Health, Department of Public Health and Primary Care, Katholieke Universiteit of Leuven (KU Leuven), 3000 Leuven, Belgium; Department of Health Protection, Laboratoire National de Santé (LNS), 1 Rue Louis Rech, L-3555 Dudelange, Luxembourg. Electronic address: An.vannieuwenhuyse@lns.
  • Oberacher H; Institute of Legal Medicine and Core Facility Metabolomics, Medical University of Insbruck, 6020 Innsbruck, Austria. Electronic address: Herbert.oberacher@i-med.ac.at.
  • Parinet J; ANSES, French Agency for Food, Environmental and Occupational Health & Safety, Laboratory for Food Safety, Pesticides and Marine Biotoxins Unit, F-94701 Maisons-Alfort, France. Electronic address: julien.parinet@anses.fr.
  • Van Poucke C; Flanders Research Institute for Agriculture, Fisheries And Food (ILVO), Brusselsesteenweg 370, 9090 Melle, Belgium. Electronic address: christof.vanpoucke@ilvo.vlaanderen.be.
  • Roskar R; University of Ljubljana, Faculty of Pharmacy, Slovenia. Electronic address: robert.roskar@ffa.uni-lj.si.
  • Togola A; BRGM, 3 avenue Claude Guillemin, 45060 Orléans, France. Electronic address: a.togola@brgm.fr.
  • Trontelj J; University of Ljubljana, Faculty of Pharmacy, Slovenia. Electronic address: jurij.trontelj@ffa.uni-lj.si.
  • Price EJ; RECETOX, Faculty of Science, Masaryk University, Kotlarska 2, Brno, Czech Republic. Electronic address: elliott.price@recetox.muni.cz.
Environ Int ; 186: 108585, 2024 Apr.
Article en En | MEDLINE | ID: mdl-38521044
ABSTRACT
The chemical burden on the environment and human population is increasing. Consequently, regulatory risk assessment must keep pace to manage, reduce, and prevent adverse impacts on human and environmental health associated with hazardous chemicals. Surveillance of chemicals of known, emerging, or potential future concern, entering the environment-food-human continuum is needed to document the reality of risks posed by chemicals on ecosystem and human health from a one health perspective, feed into early warning systems and support public policies for exposure mitigation provisions and safe and sustainable by design strategies. The use of less-conventional sampling strategies and integration of full-scan, high-resolution mass spectrometry and effect-directed analysis in environmental and human monitoring programmes have the potential to enhance the screening and identification of a wider range of chemicals of known, emerging or potential future concern. Here, we outline the key needs and recommendations identified within the European Partnership for Assessment of Risks from Chemicals (PARC) project for leveraging these innovative methodologies to support the development of next-generation chemical risk assessment.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Monitoreo del Ambiente / Exposición a Riesgos Ambientales Límite: Humans Idioma: En Revista: Environ Int Año: 2024 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Monitoreo del Ambiente / Exposición a Riesgos Ambientales Límite: Humans Idioma: En Revista: Environ Int Año: 2024 Tipo del documento: Article