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Prognosis and treatment outcomes for patients with stage IA triple-negative breast cancer.
Tarantino, Paolo; Leone, Julieta; Vallejo, Carlos T; Freedman, Rachel A; Waks, Adrienne G; Martínez-Sáez, Olga; Garrido-Castro, Ana; Lynce, Filipa; Tayob, Nabihah; Lin, Nancy U; Tolaney, Sara M; Leone, Jose P.
Afiliación
  • Tarantino P; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Leone J; Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston, MA, USA.
  • Vallejo CT; Harvard Medical School, Boston, MA, USA.
  • Freedman RA; Department of Oncology and Onco-Hematology, University of Milan, Milan, Italy.
  • Waks AG; Grupo Oncológico Cooperativo del Sur, Neuquén, Argentina.
  • Martínez-Sáez O; Grupo Oncológico Cooperativo del Sur, Neuquén, Argentina.
  • Garrido-Castro A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Lynce F; Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston, MA, USA.
  • Tayob N; Harvard Medical School, Boston, MA, USA.
  • Lin NU; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Tolaney SM; Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston, MA, USA.
  • Leone JP; Harvard Medical School, Boston, MA, USA.
NPJ Breast Cancer ; 10(1): 26, 2024 Apr 04.
Article en En | MEDLINE | ID: mdl-38575691
ABSTRACT
To evaluate the role of chemotherapy in stage IA triple-negative breast cancer, we conducted a retrospective population-based study including 8601 patients. The use of chemotherapy significantly increased from 2010 to 2019 in patients with T1b and T1c tumors (p = 0.001 and p < 0.001, respectively). Receipt of chemotherapy was associated with improved breast cancer-specific survival (BCSS, adjusted hazard ratio = 0.70; p = 0.006), particularly in patients with T1c tumors (5-year BCSS 94.5% vs. 91.2%).

Texto completo: 1 Banco de datos: MEDLINE Idioma: En Revista: NPJ Breast Cancer Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Banco de datos: MEDLINE Idioma: En Revista: NPJ Breast Cancer Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos