Intrinsic disorder: A term to define the specific physicochemical characteristic of protein conformational heterogeneity.
Mol Cell
; 84(7): 1188-1190, 2024 Apr 04.
Article
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| MEDLINE
| ID: mdl-38579677
ABSTRACT
In his commentary in this issue of Molecular Cell,1 Struhl reasons that the term "intrinsically disordered regions" represents a vague and confusing concept for protein function. However, the term "intrinsically disordered" highlights the important physicochemical characteristic of conformational heterogeneity. Thus, "intrinsically disordered" is the counterpart to the term "folded, " with neither term having specific functional implications.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Proteínas Intrínsecamente Desordenadas
Idioma:
En
Revista:
Mol Cell
Asunto de la revista:
BIOLOGIA MOLECULAR
Año:
2024
Tipo del documento:
Article