Predictors of clinical outcomes in patients with sepsis: A retrospective study from a tertiary care hospital in Pakistan.
J Pak Med Assoc
; 74(3): 608-612, 2024 03.
Article
en En
| MEDLINE
| ID: mdl-38591316
ABSTRACT
OBJECTIVE:
To assess associations between various clinic-demographic factors and clinical outcomes among patients treated for sepsis.METHODS:
The retrospective study was conducted at the Aga Khan University Hospital, Karachi, and comprised data of all patients aged >18 years diagnosed with sepsis from January to December 2019. Multivariable logistic regression was used to evaluate independent associations between predictors and outcomes. Data was analysed using R packages.RESULTS:
Of the 1,136 patients, 621(54.6%) were male and 515(45.3%) were female. The overall mean age was 59.05±16.91 years. Female gender (odds ratio 1.029; 95% confidence interval 1.03-1.64) was found to be an independent predictor of septic shock, while hypertension (odds ratio0.75; 95% confidence interval 0.59-0.95) emerged as a protective factor. Chronic kidney disease (odds ratio 1.539; 95% confidence interval 1.14-2.07) was an independent predictor of prolonged length of stay, while older age appeared to be protective (odds ratio 0.98; 95% confidence interval 0.98-0.99). Mortality was associated with a significantly lower odds of Escherichia coli on culture (odds ratio 0.26; 95% confidence interval 0.12-0.54).CONCLUSIONS:
Independent associations were found between specific patient characteristics and adverse clinical outcomes.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Sepsis
Límite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
País/Región como asunto:
Asia
Idioma:
En
Revista:
J Pak Med Assoc
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J. Pak. Med. Assoc
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Journal of the Pakistan Medical Association
Año:
2024
Tipo del documento:
Article
País de afiliación:
Pakistán