Exchangeable leaders of collectively migrating glioma abuse N-cadherin trafficking.

Kawauchi, Takeshi; Ito, Shiho

Kawauchi, Takeshi; Ito, Shiho.

Afiliación

Kawauchi T; Department of Adaptive and Maladaptive Responses in Health and Disease, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Ito S; Department of Physiology, Keio University School of Medicine, Tokyo, Japan.

J Cell Biol ; 223(6)2024 06 03.

Article en En | MEDLINE | ID: mdl-38700903

ABSTRACT

ABSTRACT

Collectively migrating cells consist of leaders and followers with different features. In this issue, Kim et al. (https//doi.org/10.1083/jcb.202401057) characterize the leader and follower cells in collective glioma migration and uncover important roles of YAP1/TAZ-mediated regulation of N-cadherin in the leader cells.

Asunto(s)

Cadherinas; Glioma; Humanos; Proteínas Adaptadoras Transductoras de Señales/metabolismo; Proteínas Adaptadoras Transductoras de Señales/genética; Antígenos CD/metabolismo; Antígenos CD/genética; Cadherinas/metabolismo; Cadherinas/genética; Movimiento Celular; Glioma/metabolismo; Glioma/patología; Glioma/genética; Transporte de Proteínas; Factores de Transcripción/metabolismo; Factores de Transcripción/genética; Proteínas Señalizadoras YAP/metabolismo

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cadherinas / Glioma Límite: Humans Idioma: En Revista: J Cell Biol Año: 2024 Tipo del documento: Article País de afiliación: Japón

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