Is neurodevelopment impaired in Brazilian children with intestinal failure on prolonged parenteral nutrition? A single center study.
Pediatr Surg Int
; 40(1): 120, 2024 May 04.
Article
en En
| MEDLINE
| ID: mdl-38702423
ABSTRACT
PURPOSE:
To assess the neurodevelopment outcomes of children younger than 42 months of age with intestinal failure (IF) using prolonged parenteral nutrition (PN) followed by a Pediatric Multidisciplinary Intestinal Rehabilitation Program from a public tertiary hospital in Brazil.METHODS:
Bayley III scale was administered in children aged 2 to 42 months with IF and receiving PN for more than 60 days. Composite scores in cognitive, motor, and language domains were analyzed. Developmental delay was defined as a performance 2 standard deviations (SD) below the average at the 3 domains. Association between Bayley III composite scores and clinical variables related to IF were tested.RESULTS:
Twenty-four children with median (IQR) age of 17.5 months (9-28.5) were studied, 58.3% were male. Developmental delay was found in 34%, 33% and 27% of the patients in cognitive, motor, and language domains, respectively. There was no significant association between the Bayley-III composite scores and length of hospitalization, prematurity, and number of surgical procedures with anesthesia.CONCLUSION:
The study demonstrated impairments in the cognitive, motor and language domains in approximately one-third of young patients with IF on prolonged PN.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Nutrición Parenteral
/
Insuficiencia Intestinal
Límite:
Child, preschool
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Female
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Humans
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Infant
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Male
País/Región como asunto:
America do sul
/
Brasil
Idioma:
En
Revista:
Pediatr Surg Int
/
Pediatr. surg. int
/
Pediatric surgery international
Asunto de la revista:
PEDIATRIA
Año:
2024
Tipo del documento:
Article
País de afiliación:
Brasil