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Current treatment options for leptospirosis: a mini-review.
Petakh, Pavlo; Behzadi, Payam; Oksenych, Valentyn; Kamyshnyi, Oleksandr.
Afiliación
  • Petakh P; Department of Biochemistry and Pharmacology, Uzhhorod National University, Uzhhorod, Ukraine.
  • Behzadi P; Department of Microbiology, Virology, and Immunology, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine.
  • Oksenych V; Department of Microbiology, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran.
  • Kamyshnyi O; Broegelmann Research Laboratory, Department of Clinical Science, University of Bergen, Bergen, Norway.
Front Microbiol ; 15: 1403765, 2024.
Article en En | MEDLINE | ID: mdl-38725681
ABSTRACT
Leptospirosis, one of the most common global zoonotic infections, significantly impacts global human health, infecting more than a million people and causing approximately 60,000 deaths annually. This mini-review explores effective treatment strategies for leptospirosis, considering its epidemiology, clinical manifestations, and current therapeutic approaches. Emphasis is placed on antibiotic therapy, including recommendations for mild and severe cases, as well as the role of probiotics in modulating the gut microbiota. Furthermore, novel treatment options, such as bacteriophages and newly synthesized/natural compounds, are discussed, and the findings are expected to provide insights into promising approaches for combating leptospirosis.
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Texto completo: 1 Banco de datos: MEDLINE Idioma: En Revista: Front Microbiol Año: 2024 Tipo del documento: Article País de afiliación: Ucrania

Texto completo: 1 Banco de datos: MEDLINE Idioma: En Revista: Front Microbiol Año: 2024 Tipo del documento: Article País de afiliación: Ucrania