End of 2022/23 Season Influenza Vaccine Effectiveness in Primary Care in Great Britain.
Influenza Other Respir Viruses
; 18(5): e13295, 2024 May.
Article
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| MEDLINE
| ID: mdl-38744684
ABSTRACT
BACKGROUND:
The 2022/23 influenza season in the United Kingdom saw the return of influenza to prepandemic levels following two seasons with low influenza activity. The early season was dominated by A(H3N2), with cocirculation of A(H1N1), reaching a peak late December 2022, while influenza B circulated at low levels during the latter part of the season. From September to March 2022/23, influenza vaccines were offered, free of charge, to all aged 2-13 (and 14-15 in Scotland and Wales), adults up to 49 years of age with clinical risk conditions and adults aged 50 and above across the mainland United Kingdom.METHODS:
End-of-season adjusted vaccine effectiveness (VE) estimates against sentinel primary-care attendance for influenza-like illness, where influenza infection was laboratory confirmed, were calculated using the test negative design, adjusting for potential confounders.METHODS:
Results In the mainland United Kingdom, end-of-season VE against all laboratory-confirmed influenza for all those > 65 years of age, most of whom received adjuvanted quadrivalent vaccines, was 30% (95% CI -6% to 54%). VE for those aged 18-64, who largely received cell-based vaccines, was 47% (95% CI 37%-56%). Overall VE for 2-17 year olds, predominantly receiving live attenuated vaccines, was 66% (95% CI 53%-76%).CONCLUSION:
The paper provides evidence of moderate influenza VE in 2022/23.Palabras clave
Texto completo:
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Banco de datos:
MEDLINE
Asunto principal:
Virus de la Influenza B
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Atención Primaria de Salud
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Vacunas contra la Influenza
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Gripe Humana
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Subtipo H3N2 del Virus de la Influenza A
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Eficacia de las Vacunas
Límite:
Adolescent
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Adult
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Aged
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Child
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Child, preschool
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Female
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Humans
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Male
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Middle aged
País/Región como asunto:
Europa
Idioma:
En
Revista:
Influenza Other Respir Viruses
Asunto de la revista:
VIROLOGIA
Año:
2024
Tipo del documento:
Article