Laser-induced optical breakdown is a prior strategy for acquired melanin-increased disorder in dermal layer.
Lasers Med Sci
; 39(1): 216, 2024 Aug 14.
Article
en En
| MEDLINE
| ID: mdl-39141143
ABSTRACT
This brief report discusses the challenges in treating dermal melanosis and the limitations of current laser treatments due to inadequate tissue penetration and potential side effects. It introduces laser-induced optical breakdown (LIOB) as a novel therapeutic approach using a picosecond laser with a diffractive lens array (DLA) to target dermal pigmentation effectively. LIOB induces multiphoton ionization, leading to melanin clearance through phagocytosis and apoptotic cell removal, while also promoting dermal remodeling and collagen synthesis. We present a case of successful treatment of dermal pigmentation in a 55-year-old woman using 755 nm-picosecond alexandrite laser therapy, demonstrating significant improvement without recurrence. The findings suggest that LIOB offers a promising solution for acquired dermal hypermelanosis by addressing both diffuse and localized pigmentation effectively, leading to skin rejuvenation with minimal downtime and high patient satisfaction.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Láseres de Estado Sólido
Límite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Lasers Med Sci
Asunto de la revista:
BIOTECNOLOGIA
/
RADIOLOGIA
Año:
2024
Tipo del documento:
Article
País de afiliación:
Taiwán