A probable neuroleptic effect on platelet monoamine oxidase in chronic schizophrenic patients.

DeLisi, L E; Wise, C D; Bridge, T P; Rosenblatt, J E; Wagner, R L; Morihisa, J; Karson, C; Potkin, S G; Wyatt, R J

DeLisi, L E; Wise, C D; Bridge, T P; Rosenblatt, J E; Wagner, R L; Morihisa, J; Karson, C; Potkin, S G; Wyatt, R J.

Psychiatry Res ; 4(1): 95-107, 1981 Feb.

Article en En | MEDLINE | ID: mdl-6111821

ABSTRACT

ABSTRACT

Platelet monoamine oxidase activity (MAO) was studied serially over time in 16 chronic schizophrenic patients when medication free and then when medicated. Thirteen of the 16 patients had significant decreases in platelet MAO activity following neuroleptic drug treatment. The change in MAO activity was found to be correlated with response to treatment and to dose of medication.

Asunto(s)

Antipsicóticos/uso terapéutico; Plaquetas/enzimología; Monoaminooxidasa/sangre; Esquizofrenia/tratamiento farmacológico; Adulto; Enfermedad Crónica; Depresión Química; Femenino; Flufenazina/uso terapéutico; Haloperidol/uso terapéutico; Humanos; Masculino; Trifluoperazina/uso terapéutico

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Banco de datos: MEDLINE Asunto principal: Esquizofrenia / Antipsicóticos / Plaquetas / Monoaminooxidasa Límite: Adult / Female / Humans / Male Idioma: En Revista: Psychiatry Res Año: 1981 Tipo del documento: Article

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