Identification of Anaplasmataceae (Haemobartonella) antigen and antibodies in systemic lupus erythematosus.

Kallick, C A; Thadhani, K C; Rice, T W

Kallick, C A; Thadhani, K C; Rice, T W.

Arthritis Rheum ; 23(2): 197-205, 1980 Feb.

Article en En | MEDLINE | ID: mdl-6153897

ABSTRACT

ABSTRACT

Free antigen related to Anaplasma marginale (AM) (Haemobartonella) was demonstrated in the glomeruli of one patient with lupus nephritis. Indirect fluorescent antibodies against this rickettsia were demonstrated in all of 22 lupus sera tested, with titers ranging from 120 to 11280. Geometric mean titer (GMT) was 116. Fifty-eight percent of 102 controls did not react to AM by indirect fluorescent antibody technique, and GMT of all controls was 10.7 Immunofluorescence was eliminated by neutralization and blocking techniques.

Asunto(s)

Anaplasmataceae/inmunología; Anticuerpos Antibacterianos; Antígenos Bacterianos; Lupus Eritematoso Sistémico/inmunología; Adulto; Animales; Bovinos; Reacciones Cruzadas; Eritrocitos/inmunología; Femenino; Técnica del Anticuerpo Fluorescente; Humanos; Glomérulos Renales/inmunología; Lupus Eritematoso Sistémico/etiología; gammaglobulinas/biosíntesis

Buscar en Google

Imprimir

XML

PubMed Links

Banco de datos: MEDLINE Asunto principal: Anaplasmataceae / Lupus Eritematoso Sistémico / Anticuerpos Antibacterianos / Antígenos Bacterianos Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies Límite: Adult / Animals / Female / Humans Idioma: En Revista: Arthritis Rheum Año: 1980 Tipo del documento: Article

Buscar en Google

Imprimir

XML

PubMed Links