[Structural polypeptide VP1 in poliovirus type 1 induced by neutralizing antibodies]. / Le polypeptide structural VP1 du poliovirus type 1 induit des anticorps neutralisants.

ABSTRACT

Anti-type 1 (Mahoney) poliovirus neutralizing antibodies were obtained by immunizing rabbits with structural polypeptide VP1. This polypeptide was isolated from the virion by PAGE-SDS electrophoresis and extracted from the gel by electroelution. Anti VP2 and anti VP3 sera prepared in the same was did not display any significant antipolio neutralizing activity.