Eukaryotic RNA polymerase II binds to nucleosome cores from transcribed genes.
Nature
; 301(5900): 482-8, 1983 Feb 10.
Article
en En
| MEDLINE
| ID: mdl-6823327
ABSTRACT
Purified RNA polymerase II from calf thymus can bind to about 15% of the nucleosome core particles prepared from mouse myeloma cells, forming a discrete complex having a sedimentation coefficient of 18S. These bound nucleosome cores are heavily enriched in transcribed DNA sequences, are deficient in histones H2A and H2B, and undergo a reversible change in structure on RNA polymerase II binding.
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Banco de datos:
MEDLINE
Asunto principal:
Transcripción Genética
/
ARN Polimerasa II
/
ARN Polimerasas Dirigidas por ADN
/
Nucleosomas
Límite:
Animals
Idioma:
En
Revista:
Nature
Año:
1983
Tipo del documento:
Article