Glomerulonephritis in a patient with sarcoidosis. Report of a case and review of the literature.

ABSTRACT

A 38-year-old woman who had severe impairment of renal function displayed crescentic glomerulonephritis on a renal biopsy specimen. Chest roentgenogram showed bilateral hilar adenopathy. A biopsy specimen of a hilar lymph nodes showed many noncaseating granulomas, consistent with sarcoidosis. Therapy with plasmapharesis, cyclophosphamide, and corticosteroids was associated with improvement of renal function and disappearance of hilar adenopathy. Based on this case and a review of the literature, sarcoidosis should be considered when studying crescentic glomerulonephritis.