Screening for congenital hypothyroidism in Turkey.
Eur J Pediatr
; 154(8): 614-6, 1995 Aug.
Article
en En
| MEDLINE
| ID: mdl-7588958
ABSTRACT
UNLABELLED A pilot study was performed to determine the incidence of congenital hypothyroidism (CH) in Turkey and to build a model for nationwide screening. From December 1991 to December 1992, 30,097 newborns were screened for CH using a primary measurement of thyroid stimulating hormone in capillary blood on days 3-5 of life. Samples were obtained in collaboration with the ongoing nationwide phenylketonuria screening programme. Eleven cases of primary CH were detected giving the incidence of 12736. Recall rate was 2.3%. Replacement therapy with L-thyroxine was started after the confirmation of diagnosis. The median age at the initiation of replacement therapy was 23 days (range 7-35 days). CONCLUSION:
The incidence of CH is notably higher in Turkey than reported in most other countries. Iodine deficiency and/or dyshormonogenesis might contribute to this high incidence. This result emphasizes the necessity of a nationwide screening programme.
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Banco de datos:
MEDLINE
Asunto principal:
Tamizaje Neonatal
/
Hipotiroidismo Congénito
Tipo de estudio:
Diagnostic_studies
/
Incidence_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
Límite:
Female
/
Humans
/
Male
/
Newborn
País/Región como asunto:
Asia
Idioma:
En
Revista:
Eur J Pediatr
Año:
1995
Tipo del documento:
Article
País de afiliación:
Turquía