[Follow-up studies of patients with negative TRH test and normal thyroid hormone levels]. / Verlaufsbeobachtungen bei Patienten mit negativem TRH-Test und normalen Schilddrüsenhormonspiegeln.
Z Gesamte Inn Med
; 48(8): 398-400, 1993 Aug.
Article
en De
| MEDLINE
| ID: mdl-8379222
The aim of the study was to assess the clinical significance of the association of a negative TRH-test with normal thyroid hormone levels. Therefore, we repeated the investigation in 63 patients one year after the first examination. In 6 patients (10%) hyperthyroidism had developed. Euthyroid autonomy was diagnosed in 11 patients (17%). A prolonged normalisation period of the pituitary-thyroid regulation after having discontinued the thyroid hormone drugs was found in 7 patients (11%). In 40% of the patients the TRH-test remained negative and in 22% of the patients the TSH-response became positive without any known reason. The findings show that a negative TRH-test and normal thyroid hormone levels do not necessarily imply subclinical hyperthyroidism.
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Banco de datos:
MEDLINE
Asunto principal:
Pruebas de Función de la Tiroides
/
Tirotropina
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Hormona Liberadora de Tirotropina
/
Hipertiroidismo
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
Límite:
Adult
/
Aged
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Female
/
Humans
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Male
/
Middle aged
Idioma:
De
Revista:
Z Gesamte Inn Med
Año:
1993
Tipo del documento:
Article