Calbindin-D28K cells in the hamster SCN express light-induced Fos.
Neuroreport
; 7(6): 1224-8, 1996 Apr 26.
Article
en En
| MEDLINE
| ID: mdl-8817537
ABSTRACT
Although the suprachiasmatic nuclei (SCN) have been intensively analyzed, they contain a population of cells that has not yet been characterized. In this study, we examined the distribution of cells immunoreactive (ir) for calbindin-D28K (CaBP), calretinin (CR), parvalbumin, vasopressin-associated neurophysin (NP), substance P (SP), vasoactive intestinal peptide (VIP), and light-induced Fos-like protein. Previously unidentified cells in the core of the hamster SCN contained CaBP. Photic stimulation during the night induced Fos expression in about 75% of the CaBP-positive SCN cells, and about 50% of the Fos-positive cells in the core region expressed CaBP. These findings provide new information in the search for the cellular localization of pacemaker cells in the SCN, as photic input entrains the circadian system, and cells that receive photic input must be either part of the clock itself, or an upstream component of the clock.
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Banco de datos:
MEDLINE
Asunto principal:
Núcleo Supraquiasmático
/
Neuropéptidos
/
Proteína G de Unión al Calcio S100
/
Proteínas Proto-Oncogénicas c-fos
/
Luz
/
Proteínas del Tejido Nervioso
Límite:
Animals
Idioma:
En
Revista:
Neuroreport
Asunto de la revista:
NEUROLOGIA
Año:
1996
Tipo del documento:
Article
País de afiliación:
Estados Unidos