Low intensity ultrasound therapy induces angiogenesis and persistent inflammation in the chronic phase of the healing process of third degree burn wounds experimentally induced in diabetic and non-diabetic rats

ABSTRACT PURPOSE: To evaluate the effects of low intensity ultrasound on the healing process of third degree burn wounds in experimentally induced diabetic Wistar rats. METHODS: One hundred rats were divided into: control group; non-diabetic treated group; diabetic control group; diabetic treated group. The therapy was performed with a 3MHz ultrasound application, pulsed emission at 100Hz frequency, modulated at 20% with a dosage of 0.5W/cm2 during three minutes throughout 30 days. The surgical debridement of the wound was performed once at day 2. The wounds were morphometrically, macroscopically and microscopically evaluated at 3, 7, 14, 21 and 30 days. RESULTS: The wound contraction and collagen quantification were higher in all treated groups. Macroscopically, necrosis was higher in the diabetic control group. Granulation tissue was higher in treated groups during the proliferative and remodeling phase. Microscopically, there were greater mononuclear inflammatory infiltration, angiogenesis and fibroblast quantification in treated groups during the proliferative and remodeling phases. CONCLUSIONS: therapeutic ultrasound is beneficial in the inflammatory and proliferative phases of the healing process because it controlled the necrotic tissue, increased the granulation tissue and wound contraction. However in the remodeling phase it is not beneficial because of the continued angiogenesis and a mononuclear inflammatory infiltration.

A importância da Liga Acadêmica de Queimaduras / The importance of the Burns Academic League

A abordagem da fisioterapia em queimaduras ainda é escassa em nosso país, porém muito necessária. Partindo deste princípio foi idealizado um projeto que visava apresentar o conteúdo sobre queimaduras aos acadêmicos da área de saúde e educação e trabalhasse em prol da prevenção de acidentes que envolvessem queimaduras. Dessa idéia surgiu a Liga Acadêmica de Queimaduras, que completa um ano de funcionamento, e vem apresentar seu trabalho científico e social desenvolvido neste primeiro ano de atuação. Obtivemos um resultado positivo, conscientizando a comunidade e envolvendo os acadêmicos no trabalho científico e social voluntário.

The approach of physical therapy in burns is still scarce in our country, but very necessary. Assuming this was planned a project to present the content on burns to the students of health care and education and works towards the prevention of accidents involving burns. Based on this idea was launched the Burns Academic League, that has one year of operation, which scientific and social activities are presented in this paper. Positive results were obtained, educating the community and involving students in scientific and social activities.