Nanotechnology in Dermatology

The scientific community and general public have been exposed to a series of achievements attributed to a new area of knowledge: Nanotechnology. Both abroad and in Brazil, funding agencies have launched programs aimed at encouraging this type of research. Indeed, for many who come into contact with this subject it will be clear the key role that chemical knowledge will play in the evolution of this subject. And even more, will see that it is a science in which the basic structure is formed by distilling different areas of inter-and multidisciplinary knowledge along the lines of new paradigms. In this article, we attempt to clarify the foundations of nanotechnology, and demonstrate their contribution to new advances in dermatology as well as medicine in general. Nanotechnology is clearly the future. .

Nevus Pigmentado Piloso Gigante: Acompanhamento clínico e histopatológico de três anos após remoção com Laser Q-Switched Nd. YAG 1064nm / Giant pigmented hairy nevus: clinical and histopathological 3-year follow-up after removal with 1, 064 nm Q-Switched Nd:YAG Laser

Os nevos melanocíticos congênitos gigantes são extremamente raros, apresentando, entretanto, risco variável de 5% a 10% de desenvolvimento de melanoma. O tratamento desse tipo de lesão utilizando lasers ainda é muito controverso, havendo relatos de grande sucesso sem evolução maligna e outros com boa resolução estética porém com malignização. Relatamos a evolução clínica e histológica do caso de paciente do sexo feminino, portadora de nevo melanocítico congênito gigante em calção de banho, após 14 sessões de laser Q-switched Nd:YAG 1064nm e três anos de acompanhamento histopatológico sem sinais de malignidade. Salienta-se a necessidade de acompanhamento histológico nesse tipo de lesão.

Giant congenital melanocytic nevi are extremely rare, however there is a 5-10% chance they will develop into melanomas. Laser-based treatment of this type of lesion is still very controversial. Some studies report great success without malignant development and others have achieved good aesthetic results but with malignancy. This article describes the clinical and histological development of a case of a female patient with a giant congenital melanocytic bathing trunk nevus, after 14 sessions of 1,064 nm Q-Switched Nd:YAG laser and three years of follow-up without histological signs of malignancy. The authors highlight the need for histological monitoring of this type of lesions.