Impacto del uso de anillos y uñas esmaltadas en la calidad de la higiene de manos en el personal de salud / Impact of the use of rings and nail polish on hand hygiene quality in healthcare workers

Resumen Introducción: Las infecciones asociadas a la atención de salud son un problema frecuente en el ambiente hospitalario. La higiene de manos es la medida más efectiva para su prevención. El uso de ciertos accesorios en las manos podría disminuir su efectividad y favorecer la transmisión horizontal de agentes infecciosos. Objetivo: Revisar los estudios publicados que evalúan el impacto del uso de anillos y uñas esmaltadas en la calidad de la higiene de manos en trabajadores de la salud. Métodos: Búsqueda no sistemática en base de datos PUBMED/MEDLINE (1978-2018) de estudios en los cuales se mide la calidad de la higiene de manos o lavado quirúrgico, mediante cultivos cuantitativos o tinciones fluorescentes. Resultados: Uso de anillos: Trece de 51 artículos cumplían los criterios de inclusión. Siete fueron realizados en unidades clínicas, y en todos ellos éste se asoció a menor calidad de la higiene de manos (la mayoría de baja calidad). Contrariamente, en tres de cuatro estudios primarios realizados en pabellón (de baja calidad), su uso no impactó en la calidad del lavado quirúrgico. Igualmente, dos revisiones sistemáticas obtuvieron similares conclusiones. Uñas esmaltadas: siete de 54 artículos fueron incluidos. En cuatro hubo resultados discordantes (la mayoría de baja calidad). En un estudio controlado se observó reducción en la calidad del lavado quirúrgico sólo cuando el esmalte estaba dañado. El esmalte gel se asoció a menor calidad de la higiene de manos en dos estudios experimentales. Conclusiones: No existe evidencia de calidad suficiente para asociar el uso de estos accesorios con reducción en la calidad de la higiene de manos. Tampoco queda demostrada su inocuidad. En base a la evidencia disponible (la mayoría de baja calidad), se observó un impacto negativo del uso de anillos en unidades clínicas y también de uñas con esmalte dañado en pabellones quirúrgicos. Se requieren estudios de mejor calidad para abordar estos relevantes tópicos.

Abstract Background: Health-care-associated infections are a frequent problem in hospital environments. Hand hygiene is the most effective measure to prevent outbreaks. The use of certain accessories could decrease its effectiveness, facilitating horizontal transmission of pathogens. Objective: Analyze the evidence that assess the impact of the use of rings and nail polish on hand hygiene quality in healthcare workers. Methods: Non-systematic search in PUBMED/MEDLINE database (1978-2018) of studies in which the quality of hand hygiene or surgical washing is measured, using quantitative cultures or fluorescent stains. Results: Wearing rings: 13 studies met the inclusion criteria. Seven were carried out in general wards. In all of them the use of rings was associated with lower quality of hand hygiene (the majority of low quality). Contrarily, in 3 of 4 primary studies carried out in the operating rooms (of low quality), their use did not affect the quality of surgical washing. Similarly, two systematic reviews obtained similar conclusions. Nail polish: 7 of 54 studies met the inclusion criteria. In four of them there were discordant results (the majority of low quality). One RCT showed a reduction in the quality of surgical washing only when the nail polish was damaged. Gel nail polish was associated with lower quality in two experimental studies. Conclusions: There is insufficient evidence to associate the use of these accessories with the reduction in the quality of hand hygiene. Its safety was not proven neither. Based on the available evidence (the majority of low quality), a negative impact of the use of rings in clinical units and also of damaged nail polish in operating rooms was observed. Better quality studies are required to address these relevant issues.

The hierarchical structure of fear of personal death: from the general factor to specific forms

Abstract Purpose In the present study, we aimed to integrate unidimensional and multidimensional perspectives of the construct of the fear of personal death (FOPD). It has been assumed that (a) there is one general factor of FOPD, reflecting the unidimensional perspective and that (b) FOPD assumes a hierarchical structure reflecting the multidimensional perspective. Methods We administered the Death and Dying Anxiety Inventory (FVTS, Ochsmann, 1993) to 1217 Polish participants (602 women and 615 men) aged between 18 and 89 ( M Age = 31.13; SD Age = 12.65). Results The results of the bi-factor model of the confirmatory factor analysis proved the existence of a FOPD general factor. Using the bass-ackwards approach, we provided evidence on the hierarchical structure of FOPD, which stresses that specific types of FOPD distinguished in the FVTS, which, on a higher level, make up the factors of threats to self-fulfilling existence, threats to well-being and threats of physical destruction, which in turn depend on the subject's perspective: the physical self and/or the symbolic self. Conclusion The current study demonstrates that unidimensional and multidimensional approaches to FOPD do not necessarily exclude one another. The unidimensional approach to FOPD seems to be most appropriate for studying the intensity of FOPD, while the multidimensional approach seems to be more suitable for studying the individual differences in how people give meaning to FOPD.

Insomnia and the level of stress among students in Krakow, Poland / Insônia e nível de estresse em estudantes de Cracóvia, Polônia

Abstract Introduction: Stress and insomnia are increasing problems in young people in highly developed countries. They influence both the physical and psychological aspects of life and seem to be related to each other. Various strategies to cope with stress exist and can be used to reduce its level. The main goal of our study was to find a relationship between insomnia, stress, stress-coping strategies and selected social and medical factors among students. Methods: A cross-sectional study was conducted in March 2017 among students of seven public Krakow universities, using the Perceived Stress Scale 10, an abbreviated version of the Coping Orientation to Problems Experienced inventory (mini-COPE inventory) and the Athens Insomnia Scale. In the statistical analysis, the chi-square, Student's t test and Spearman's rank correlation coefficient were used. Results: A total of 264 students aged 22.22±1.5 years were involved in the study. High stress levels occurred in 10% of the respondents. A statistically higher level of stress was revealed in people suffering from chronic diseases (p=0.006) and in cigarette smokers (p=0.004). The most common stress-coping strategies were active coping and planning. Insomnia was present in 19.7% of the students. Insomnia level was correlated with the intensity of perceived stress (p=0.00; r=0.44). Conclusions: According to our study, one tenth of Krakow students perceive a high level of stress, and one fifth of the respondents suffer from insomnia. There is a strong positive correlation between level of insomnia and level of stress. To ensure high quality of life, problems such as stress and insomnia should be taken into consideration by every general practitioner.

Resumo Introdução: Estresse e insônia são problemas cada vez mais presentes em pessoas jovens em países altamente desenvolvidos. Eles influenciam tanto os aspectos físicos quanto os psicológicos da vida e parecem estar relacionados entre si. Várias estratégias de enfrentamento (coping) do estresse existem e podem ser usadas para reduzir seu nível. O objetivo principal deste estudo foi investigar a relação entre insônia, estresse, estratégias de coping, e certos fatores sociais e médicos em estudantes. Métodos: Um estudo transversal foi conduzido em março de 2017 com estudantes de sete universidades públicas da Cracóvia, na Polônia, utilizando a Escala de Estresse Percebido 10, uma versão abreviada do Inventário para Medir Estratégias de Enfrentamento de Estresse (mini-COPE) e a Athens Insomnia Scale. Na análise estatística, foram utilizados os testes qui-quadrado, t de Student e o coeficiente de correlação de Spearman. Resultados: Um total de 264 estudantes com idade média de 22,22±1,5 anos foram incluídos no estudo. Altos níveis de estresse ocorreram em 10% dos respondentes. Um nível estatisticamente mais alto de estresse foi revelado em pessoas sofrendo de doenças crônicas (p=0,006) e em fumantes (p=0,004). As estratégias de coping mais comuns foram coping ativo e planejamento. A insônia esteve presente em 19,7% dos alunos. O nível de insônia se correlacionou com a intensidade do estresse percebido (p=0,00; r=0,44). Conclusões: De acordo com este estudo, um décimo dos estudantes de Cracóvia percebe um alto nível de estresse, e um quinto dos respondentes sofrem de insônia. Há uma forte correlação positiva entre nível de insônia e nível de estresse. Para garantir alta qualidade de vida, problemas como estresse e insônia devem ser levados em consideração pelo médico generalista.

Autoria científica do doutor Chernoviz entre a vulgarização da medicina e a formação profissional: o caso do Dicionário de medicina popular, 1842-1890 / The scientific authorship of Doctor Chernoviz, from the popularization of medicine to professional training: the Dicionário de medicina popular, 1842-1890

Resumo O artigo traz reflexões em torno da autoria científica do doutor Chernoviz a partir de seu Dicionário de medicina popular, com seis edições entre 1842 e 1890. Na primeira seção do texto discute-se a inserção de Chernoviz nos regimes de autoria científica vigentes no campo médico carioca. Em seguida, analisam-se os argumentos desenvolvidos pelo autor para justificar a publicação de um livro de vulgarização da ciência médica num momento em que o campo médico militava pela exclusividade do exercício da medicina. Por fim, sugerem-se novos sentidos em torno da autoria científica de Chernoviz a partir das constatações dos usos e das leituras do Dicionário por parte de um público de iniciados.

Abstract This article reflects on the scientific authorship of Pedro Luiz Napoleão Chernoviz, based on his Dicionário de medicina popular, which was published in six editions between 1842 and 1890. The first part of the text discusses Chernoviz's position within the regimes of scientific authorship which were present in the medical community in Rio de Janeiro. Next, we analyze the author's arguments justifying a text that popularized medical science while this field strove for exclusivity in the practice of medicine. Finally, we suggest new meanings around Chernoviz's scientific authorship based on how the Dicionário was used and read by an initiated public.

Eliasz Cynamon e o Programa do Rio Doce (Sesp): contribuição de fontes para a história das ações de saúde e saneamento no Brasil, 1952-1960 / Eliasz Cynamon and the Rio Doce Program (SESP): contribution of sources to the history of health and sanitation actions in Brazil, 1952-1960

Resumo Apresenta pesquisa acerca da atuação de Szachna Eliasz Cynamon no Programa Vale do Rio Doce (1952-1960). Privilegiamos como fonte de consulta os acervos dos departamentos de Arquivo e Documentação e de Saneamento e Saúde Ambiental, na Fiocruz, e o ainda pertencente à família. Na época, a região contava com altos índices de malária. Cynamon, nascido na Polônia e imigrado ainda criança nos anos 1930 para o Brasil, onde se graduaria em engenharia sanitária, foi contratado para atuar em Colatina (ES) e em Governador Valadares (MG), entre 1952 e 1960. Nessas localidades, dedicou-se ao tratamento e abastecimento de água e esgoto sanitário, além de realizar cursos de educação sanitária para a população local, como parte de acordo de cooperação Brasil-EUA.

Abstract Research into the work of Szachna Eliasz Cynamon in the Rio Doce Valley Program (1952-1960) is presented. The key sources are from the Department of Archives and Documentation and the Department of Sanitation and Environmental Health at Fiocruz, as well as the family's own archive. At the time, the rates of malaria in the region were high. Born in Poland, Cynamon migrated to Brazil in the 1930s while still a child, where he graduated in sanitary engineering. He was hired to work in Colatina (Espírito Santo) and Governador Valadares (Minas Gerais) between 1952 and 1960, focusing on sewage and water treatment and supply, while also holding sanitation education courses for the local people as part of a Brazil-USA cooperation agreement.

Indirect self-destructiveness in individuals with schizophrenia

Objective: To explore the indirect self-destructiveness syndrome in patients with schizophrenia. Methods: Two hundred individuals with paranoid schizophrenia (117 men and 83 women, mean age 37.15 years), all in remission, were examined using the Polish version of the Chronic Self-Destructiveness Scale. Two hundred well-matched healthy individuals served as a control group. Results: The intensity of indirect self-destructiveness was greater in the schizophrenia group than in controls. The intensity of each manifestation was as follows (in decreasing order): helplessness and passiveness in the face of difficulties (A5), personal and social neglects (A3), lack of planfulness (A4), poor health maintenance (A2), transgression and risk (A1). Conclusion: Patients with schizophrenia displayed more behaviors that were indirectly self-destructive than healthy controls; they scored better than healthy controls only on caring for their own health. The patients showed the lowest intensity of behaviors connected with the active form of indirect self-destructiveness, and the highest intensity of behaviors connected with the passive form. These findings may enable delivery of more effective forms of pharmacological and psychosocial help to patients with schizophrenia.

Craniometric characteristics and cranial indices of Polish heath sheep rams ­ extended data / Características craneométricas e índices craneales de ovejas heath polacas - datos ampliados

The study was conducted on the mouflon-derived horned sheep of the preserved Polish Heath Sheep breed. In this study, basic skull measurements of 24 skulls of the rams of different age: 1 day, 90 days, 210 days, 270 days, 3 and 6 years, were analyzed. The weight of each skull was determined, as well as 43 craniometric characteristics were measured, and cranial cavity volume and viscerocranial and neurocranial indices were calculated. From birth to the age of 6 years, the greatest length of the skull, the condylobasal length and the length of the cheek-tooth row increased two-fold. To day 210 of age, the bony housing for eyeball and its organs grew intensively. To day 270 of age, the largest increase was characteristic of the elements of the angular length of the neurocranium and its breadth. The structural elements characterizing both the breadth and the length of the viscerocranium developed to the age of 6 years. A significant (P0.05), decreasing with age, value of the cephalic index was observed, being mostly affected by development of the squamous part of the frontal bone with its orbital part and the orbital margin.

El estudio se realizó en la raza preservada de ovejas Heath, derivadas del Muflón. En este estudio se analizaron las mediciones craneales básicas de 24 cráneos de carneros de diferentes edades: 1 día, 90 días, 210 días, 270 días, 3 y 6 años. Se determinó el peso de cada cráneo, se midieron 43 características craneométricas y se calculó el volumen de la cavidad craneal y los índices viscerocraneales y neurocraneales. Desde el nacimiento hasta la edad de 6 años, la longitud más grande del cráneo, la longitud del cóndilo y la longitud de la hilera del diente de la mejilla aumentó dos veces. A los 210 días de edad, la cubierta ósea para el bulbo ocular y sus órganos creció intensivamente. Al día 270 de edad, el mayor incremento fue la longitud angular del neurocráneo y su amplitud. Los elementos estructurales que caracterizan tanto el ancho como la longitud del viscerocráneo se desarrollaron a la edad de 6 años. Se observó un valor significativo (P0,05), decreciente con la edad, del índice cefálico, siendo afectado principalmente por el desarrollo de la parte escamosa del hueso frontal con su parte orbitaria y el margen orbital.

Using the Portuguese version of the Bicultural Scale in Brazil / O uso da versão em português da Escala de Biculturalidade no Brasil

Abstract Introduction: Brazil has received influxes of people, mainly from Africa, Europe and Japan, forming one of the most heterogeneous populations in the world. Some groups, particularly in Southern Brazil, have retained their original cultural traditions, whilst acquiring elements of the typical local Brazilian cultural identity. This is the first study designed to formally evaluate biculturality in Brazil. Objective: To psychometrically assess and validate the Portuguese version of the Bicultural Scale (BS) in Brazil. Methods: The BS was adapted and translated to Portuguese and tested for the first time in Brazil in a sample of descendants (n = 160) from four immigrant groups and respective locations in Southern Brazil. A series of psychometric tests were conducted in order to examine the validity of the Portuguese version of the BS. Analyses of variance across scores for all subgroups were also conducted. Results: Factor analysis revealed two main factors contributing to most of the variance in scores. The 10 items measuring affiliation with minority cultural characteristics and the typical Brazilian culture yielded Cronbach's alpha coefficients of 0.69 and 0.78 respectively, whereas the overall Cronbach's alpha for all 20 items of the BS was 0.67. There was a significant correlation between items related to the typical Brazilian culture and the generation since immigration of research participants (r = 0.23, p = 0.004). The mean time taken to complete the questionnaire was 7.4 minutes. Conclusion: The results indicate that the Portuguese version of the BS is a valid, reliable and easy-to-use instrument to assess biculturality experienced by descendants of immigrants in southern Brazil.

Resumo Introdução: O Brasil recebeu afluxo de imigrantes principalmente da África, Europa e Japão, formando uma das populações mais heterogêneas do mundo. Alguns grupos, particularmente no Sul do Brasil, têm mantido suas tradições culturais originais, ao mesmo tempo que adquirem elementos típicos da identidade cultural brasileira local. Este é o primeiro estudo a avaliar formalmente a biculturalidade no Brasil. Objetivo: Avaliação psicométrica e validação da versão em português da Escala de Biculturalidade (EB) no Brasil. Métodos: A EB foi adaptada e traduzida para o português e testada pela primeira vez no Brasil em uma amostra de descendentes de quatro grupos de imigrantes (n = 160) em diferentes localizações no Sul do Brasil. Uma série de testes psicométricos foram aplicados a fim de examinar a validade da versão em português da EB. Análises de variância através dos escores obtidos em cada subgrupo também foram conduzidas. Resultados: A análise fatorial revelou que dois fatores principais contribuem para a maioria da variância nos escores. Os 10 items que medem afiliação com características culturais minoritárias e cultura típica brasileira demonstraram índice de Cronbach de 0,69 e 0,78, respectivamente, enquanto que o alfa global de Cronbach para todos os 20 itens da EB foi de 0,67. Houve correlação significativa entre os itens relacionados à cultura típica brasileira e a geração dos voluntários desde o período de imigração (r = 0,23, p = 0,004). O tempo médio para completar o questionário foi de 7,4 minutos. Conclusões: Os resultados indicam que a versão em português da EB é um instrumento válido, confiável e de fácil utilização para avaliar expêriencias de biculturalidade de descendentes de imigrantes no Sul do Brasil.

First- Versus Second-Generation Drug-Eluting Stents in Acute Coronary Syndromes (Katowice-Zabrze Registry) / Stents Farmacológicos de Primeira Versus Segunda Geração na Síndrome Coronariana Aguda (Registro Katowice-Zabrze)

Abstract Background: There are sparse data on the performance of different types of drug-eluting stents (DES) in acute and real-life setting. Objective: The aim of the study was to compare the safety and efficacy of first- versus second-generation DES in patients with acute coronary syndromes (ACS). Methods: This all-comer registry enrolled consecutive patients diagnosed with ACS and treated with percutaneous coronary intervention with the implantation of first- or second-generation DES in one-year follow-up. The primary efficacy endpoint was defined as major adverse cardiac and cerebrovascular event (MACCE), a composite of all-cause death, nonfatal myocardial infarction, target-vessel revascularization and stroke. The primary safety outcome was definite stent thrombosis (ST) at one year. Results: From the total of 1916 patients enrolled into the registry, 1328 patients were diagnosed with ACS. Of them, 426 were treated with first- and 902 with second-generation DES. There was no significant difference in the incidence of MACCE between two types of DES at one year. The rate of acute and subacute ST was higher in first- vs. second-generation DES (1.6% vs. 0.1%, p < 0.001, and 1.2% vs. 0.2%, p = 0.025, respectively), but there was no difference regarding late ST (0.7% vs. 0.2%, respectively, p = 0.18) and gastrointestinal bleeding (2.1% vs. 1.1%, p = 0.21). In Cox regression, first-generation DES was an independent predictor for cumulative ST (HR 3.29 [1.30-8.31], p = 0.01). Conclusions: In an all-comer registry of ACS, the one-year rate of MACCE was comparable in groups treated with first- and second-generation DES. The use of first-generation DES was associated with higher rates of acute and subacute ST and was an independent predictor of cumulative ST.

Resumo Fundamento: Os dados sobre o desempenho dos diferentes tipos de stents farmacológicos (SF) no cenário agudo e da vida real são escassos. Objetivo: Comparar a segurança e a eficácia dos SF de primeira e de segunda geração em pacientes com síndrome coronariana aguda (SCA). Métodos: Este registro arrolou pacientes consecutivos com diagnóstico de SCA e tratados com intervenção coronariana percutânea e implantação de SF de primeira ou segunda geração em seguimento de 1 ano. O desfecho primário 'eficácia' foi definido como eventos cardíacos adversos maiores (ECAM), um composto de morte por todas as causas, infarto do miocárdio não fatal, revascularização de vaso-alvo e acidente vascular encefálico. O desfecho primário 'segurança' foi trombose de stent (TS) definitiva em 1 ano. Resultados: Do total de 1.916 pacientes arrolados, 1.328 foram diagnosticados com SCA. Desses, 426 foram tratados com SF de primeira geração e 902, com SF de segunda geração. Não houve diferença significativa na incidência de ECAM entre os dois tipos de SF em 1 ano. A taxa de TS aguda e subaguda foi maior com SF de primeira geração do que com os de segunda geração (1,6% vs. 0,1%, p < 0,001; e 1,2% vs. 0,2%, p = 0,025, respectivamente), mas não houve diferença para TS tardia (0,7% vs. 0,2%, respectivamente, p = 0,18) nem para sangramento gastrointestinal (2,1% vs.1,1%, p = 0,21). Na regressão de Cox, o SF de primeira geração foi preditor independente para TS cumulativa [HR 3,29 (1,30-8,31); p = 0,01]. Conclusões: No registro de SCA, a taxa de ECAM em 1 ano foi comparável nos grupos tratados com SF de primeira e de segunda geração. O uso de SF de primeira geração associou-se a maiores taxas de TS aguda e subaguda, sendo um preditor independente para TS cumulativa.

La vida como actividad normativa y auto-realización: debate en torno al concepto de normatividad biológica en Goldstein y Canguilhem / Life as regulatory activity and self-realization: debate surrounding the concept of biological regulation in Goldstein and Canguilhem

La influencia de Kurt Goldstein en el pensamiento de Georges Canguilhem se extendió a lo largo de toda su obra. El presente trabajo pretende recuperar esta relación con el objeto de realizar un estudio de la norma como nexo o conexión entre el concepto y la vida. En consecuencia, este trabajo será una reflexión sobre el planteamiento de la vida como actividad normativa y autorealización. Para ello, será necesario resignificar los conceptos de salud y enfermedad, y atravesar el camino que va de uno a otro. Al final de este camino, se encontrará que estos conceptos permiten explicar la identidad entre el concepto y la vida, lo cual conduce a la conclusión inesperada que la cura es, en definitiva, autocuración.

The influence of Kurt Goldstein on the thinking of Georges Canguilhem extended throughout his entire work. This paper seeks to examine this relationship in order to conduct a study of the norm as a nexus or connection between the concept and life. Consequently, this work will be a reflection on the approach to life as a regulatory activity and self-realization. For this, it will be necessary to redefine the concepts of health and disease, and make a crossover between the two. At the end of this trajectory, it will be found that these concepts can explain the identity between the concept and life, which leads to the unexpected conclusion that the cure is ultimately self-healing.

Proteus mirabilis biofilm - Qualitative and quantitative colorimetric methods-based evaluation

Proteus mirabilis strains ability to form biofilm is a current topic of a number of research worldwide. In this study the biofilm formation of P. mirabilis strains derived from urine of the catheterized and non-catheterized patients has been investigated. A total number of 39 P. mirabilis strains isolated from the urine samples of the patients of dr Antoni Jurasz University Hospital No. 1 in Bydgoszcz clinics between 2011 and 2012 was used. Biofilm formation was evaluated using two independent quantitative and qualitative methods with TTC (2,3,5-triphenyl-tetrazolium chloride) and CV (crystal violet) application. The obtained results confirmed biofilm formation by all the examined strains, except quantitative method with TTC, in which 7.7% of the strains did not have this ability. It was shown that P. mirabilis rods have the ability to form biofilm on the surfaces of both biomaterials applied, polystyrene and polyvinyl chloride (Nelaton catheters). The differences in ability to form biofilm observed between P. mirabilis strains derived from the urine of the catheterized and non-catheterized patients were not statistically significant.

Prevalence of resistance to aminoglycosides and fluoroquinolones among Pseudomonas aeruginosa strains in a University Hospital in Northeastern Poland

The present study was conducted to investigate the prevalence of genes encoding resistance to aminoglycosides and fluoroquinolones among twenty-five Pseudomonas aeruginosa isolated between 2002 and 2009. In PCR, following genes were detected: ant(2")-Ia in 9 (36.0%), aac(6')-Ib in 7 (28.0%), qnrB in 5 (20.0%), aph(3")-Ib in 2 (8.0%) of isolates.

Molecular epidemiology of Candida albicans and Candida glabrata strains isolated from intensive care unit patients in Poland

Over the last decades, Candida spp have been responsible for an increasing number of infections, especially in patients requiring intensive care. Knowledge of local epidemiology and analysis of the spread of these pathogens is important in understanding and controlling their transmission. The aim of this study was to evaluate the genetic diversity of 31 Candida albicans and 17 Candida glabrata isolates recovered from intensive care unit patients from the tertiary hospital in Krakow between 2011-2012. The strains were typed by random amplified polymorphic DNA (RAPD) polymerase chain reaction using five primers (CD16AS, HP1247, ERIC-2, OPE-3 and OPE-18). The results of the present investigation revealed a high degree of genetic diversity among the isolates. No clonal relationship was found among the C. albicans strains, whereas two C. glabrata isolates were identical. The source of Candida infection appeared to be mostly endogenous; however, the presence of two clonal C. glabrata strains suggested the possibility of cross-transmission of these pathogens. Our study confirmed the high discriminatory power of the RAPD technique in the molecular typing of Candida clinical isolates. This method may be applied to the evaluation of transmission routes of pathogenic fungi on a local level.

A imigração polonesa para São Paulo no pós-Segunda Guerra Mundial no quadro das entradas dos "deslocados de guerra": 1947 a 1951 / /Polish immigration to São Paulo after World War II in the context of the immigrations of displaced persons: 1947-1951 / /La inmigración polonesa hacia São Paulo en la Pos Segunda Guerra Mundial en el marco de los ingresos de los desplazados de guerra: 1947 a 1951

O presente trabalho se insere no âmbito da história social da imigração para São Paulo, focalizando especificamente o período comumente classificado como a retomada da imigração, no pós-Segunda Guerra Mundial, quando as entradas se dividem basicamente em dois momentos: 1947-1951, com o apoio da Organização Internacional das Migrações (OIR); e 1952-1980, com o apoio do Comitê Intergovernamental para as Migrações Europeias (Cime). O estudo enfoca a nacionalidade polonesa no quadro da imigração dos chamados "deslocados de guerra", provenientes dos campos de refugiados da Alemanha e da Áustria. Com base na documentação do Memorial do Imigrante, sistematizada em um banco de dados, e nos artigos publicados na Revista de Imigração e Colonização (RIC), procura-se contextualizar a discussão do período, sobre a necessidade e conveniência ou não da entrada desses imigrantes deslocados que foram introduzidos graças a acordos entre o Brasil e a OIR, além de traçar o perfil desses imigrantes, que formavam o maior grupo entre as nacionalidades entradas no período. O foco na imigração polonesa do pós-guerra ressalta a especificidade desse fluxo, cujo perfil se diferencia das levas anteriores num contexto marcado, preferencialmente, pela proteção ao trabalhador nacional e ao migrante interno...

This paper deals with the social history of the immigration to São Paulo. It focuses specifically on the period that is usually known as the resumption of immigration after World War II, when the arrivals of immigrants were divided basically into two periods: 1947-1951, with backing from the International Organization for Migration (IOM), and from 1952 to 1980, with the support of the Intergovernmental Committee for European Migration (ICEM). This paper focuses on the so-called "displaced persons" of Polish nationality, one among many groups of different nationalities who were freed from the refugee camps in Germany and Austria. This study was supported by documentation from the Immigrant Memorial, which has been systemized into a database, and is based on articles published in the Journal of Immigration and Colonization (JIC). The aim of this study is to contextualize the discussion on the need and convenience of the arrival of these displaced Polish immigrants, who were taken in through agreements between Brazil and the IRO at that time. This paper also outlines the profile of these immigrants, characterized as the largest group among the nationalities that arrived in Brazil during that period. The focus on post-war Polish immigration indicates the specific character of this group, whose profile differed from previous waves of immigrants to Brazil in a context strongly marked by movements to protect Brazilian workers and internal migrants...

El presente artículo se inserta en el ámbito de la historia social de la inmigración hacia São Paulo, enfocando específicamente el periodo que se suele clasificar como la retomada de la inmigración, en la pos Segunda Guerra Mundial, cuando las entradas se dividen básicamente en dos periodos: 1947-1951, con el apoyo de la Organización Internacional de las Migraciones (OIR) y 1952-1980, con el apoyo del Comité Intergubernamental para las Migraciones Europeas (CIME). Enfoca la nacionalidad polonesa en el marco de la inmigración de los chamados "desplazados de guerra", constituidos por personas provenientes de distintas ciudades en los campos de refugiados de Alemania y Austria. Apoyado en la documentación del Memorial del Inmigrante, sistematizada en un banco de datos, y en los artículos publicados en la Revista de Imigração e Colonização (RIC), tiene el objetivo de contextualizar la discusión del periodo, sobre la necesidad y la conveniencia del ingreso de dichos inmigrantes desplazados que fueron introducidos gracias a acuerdos entre Brasil y la OIR, además de trazar el perfil de estos inmigrantes, que se caracterizaban como el mayor grupo entre las nacionalidades que ingresaron en el mencionado periodo. El enfoque en la inmigración polonesa de la posguerra destaca la especificidad de este flujo, cuyo perfil se diferencia de los flujos anteriores en un contexto marcado preferentemente por la protección al trabajador nacional y al migrante interno...

How many Babinski's signs are there? / Quantos sinais de Babinski existem?

In addition to the famous sign described by Joseph Babinski, which is also known as Babinski's reflex, there are references in the literature to various other signs described by this famous disciple of J-M Charcot. This article reviews all the neurological signs described by Babinski.

Além do famoso sinal descrito por Joseph Babinski, também definido como reflexo de Babinski, existem referências na literatura mundial de vários outros sinais descritos pelo famoso discípulo de J-M Charcot. Este artigo apresenta uma revisão de todos os sinais neurológicos descritos pelo professor Babinski.

Straminipilous organisms growing on herbivorous pirapitinga (Piaractus brachypomus) and carnivorous piranha (Pygocentrus nattereri) from Poland / Organismos stramenophila em crescimento na herbívora pirapitinga (Piaractus brachypomus) e na carnívora piranha (Pygocentrus nattereri) da Polônia

We investigated the growth of straminipilous organisms on the skin, muscles and liver of herbivorous pirapitinga (Piaractus brachypomus) and carnivorous piranha (Pygocentrus nattereri) in water of three different eutrophication levels. Sixteen straminipilous organism species were found growing on the investigated body parts of both species of fish used as baits. The higher number of species was found on the baits of carnivorous species (15) when compared with the ones from the herbivorous pirapitinga (10 species). The highest number of straminipilous organisms species developed on the skin of both species of fish. The highest number of species of straminipilous organisms was observed growing in the water of the BiaBa river (middle eutrophication), while the lowest number occurred in the baits of vessels with water from the Dojlidy pond (low eutrophication).

Investigamos o crescimento de organismos stramenophila sobre a pele, músculos e fígado da herbívora pirapitinga (Piaractus brachypomus) e da carnívora piranha (Pygocentrus nattereri) em águas de três diferentes níveis de eutrofização. Dezesseis espécies de organismos stramenophila foram encontradas crescendo sobre as partes do corpo investigadas de ambas as espécies de peixes utilizadas como cobaias. O maior número de espécies foi encontrado em cobaias de espécies carnívoras (15), quando comparado com o da herbívora pirapitinga (10 espécies). A maioria das espécies de organismos stramenophila desenvolveu-se sobre a pele de ambas as espécies de peixes. O maior número de espécies de organismos stramenophila foi observado em crescimento nas águas do rio BiaBa (eutrofização do meio), enquanto o número mais baixo ocorreu em cobaias de vasos com água do lago de Dojlidy (eutrofização baixa).

Genetic polymorphism of alcohol-metabolizing enzyme and alcohol dependence in Polish men

Alcohol dependence poses a serious medical and sociological problem. It is influenced by multiple environmental and genetic factors, which may determine differences in alcohol metabolism. Genetic polymorphism of the enzymes involved in alcohol metabolism is highly ethnically and race dependent. The purpose of this study was to investigate the differences, if present, in the allele and genotype frequency of alcohol dehydrogenase 1B (ADH1B), ADH1C and the microsomal ethanol-oxidizing system (MEOS/CYP2E1) between alcohol-dependent individuals and controls and also to determine if these genotypes cause a difference in the age at which the patients become alcohol dependent. The allele and genotype frequencies of ADH1B, ADH1C, and CYP2E1 were determined in 204 alcohol dependent men and 172 healthy volunteers who do not drink alcohol (control group). Genotyping was performed by PCR-RFLP methods on white cell DNA. ADH1B*1 (99.3 percent) and ADH1C*1 (62.5 percent) alleles and ADH1B*1/*1 (N = 201) and ADH1C*1/*1 (N = 85) genotypes were statistically more frequent among alcohol-dependent subjects than among controls (99.3 and 62.5 percent, N = 201 and 85 vs 94.5 and 40.7 percent, N = 153 and 32, respectively). Differences in the CYP2E1 allele and genotype distribution between groups were not significant. The persons with ADH1C*1/*1 and CYP2E1*c1/*c2 genotypes became alcohol dependent at a considerably younger age than the subjects with ADH1C*1/*2, ADH1C*2/*2 and CYP2E1*c1/*c1 genotypes (28.08, 25.67 years vs 36.0, 45.05, 34.45 years, respectively). In the Polish men examined, ADH1C*1 and ADH1B*1 alleles and ADH1C*1/*1 and ADH1B*1/*1 genotypes favor alcohol dependence. The ADH1B*2 allele may protect from alcohol dependence. However, subjects with ADH1C*1/*1 and CYP2E1*c1/*c2 genotypes become alcohol dependent at a considerably younger age than the subjects with ADH1C*1/*2, ADH1C*2/*2 and CYP2E1*c1/*c1 genotypes.