Thermocoagulation as a Surgical Approach for the Treatment of Obsessive-Compulsive Disorder in Refractory Patients: Systematic Review
Arq. bras. neurocir
; 40(4): 333-338, 26/11/2021. tab
Article
em En
| LILACS
| ID: biblio-1362075
Biblioteca responsável:
BR1.1
ABSTRACT
Obsessive-compulsive disorder (OCD), a disabling chronic neuropsychiatric disease, entails high economic costs to society and has high morbidity and mortality rates. The first-line treatments for OCD are selective serotonin reuptake inhibitors and cognitivebehavioral therapy. However, this disorder has the highest refractory index to noninvasive treatment. Alternatively, ablative thermocoagulation neurosurgical techniques have shown efficacy and few adverse effects. The present systematic review aimed to identify validated protocols to observe the effectiveness of ablative procedures in the treatment of severe and refractory OCD, as well as their possible adverse effects and benefits. This review supports the effectiveness of ablative methods by presenting them as a safe non-experimental therapeutic option for cases of highlyrefractory OCD. Additional relevant findings were the improvement in cognitive function, functional capacity, affective orientation, and quality of life, which contribute to the destigmatization of this surgical technique. Further controlled studies may lead to the individualization of recommendations of targets for ablative thermocoagulation.
Palavras-chave
Texto completo:
1
Bases de dados:
LILACS
Assunto principal:
Eletrocoagulação
/
Transtorno Obsessivo-Compulsivo
Tipo de estudo:
Diagnostic_studies
/
Guideline
/
Prognostic_studies
/
Systematic_reviews
Idioma:
En
Revista:
Arq. bras. neurocir
Assunto da revista:
Cirurgia
/
NEUROCIRURGIA
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Brasil