Analysis of the biocompatibility of a biocelulose and a poly L- lactic acid membrane
Braz. j. oral sci
; 21: e220616, jan.-dez. 2022. ilus
Article
em En
| LILACS, BBO
| ID: biblio-1393329
Biblioteca responsável:
BR218.1
ABSTRACT
The use of selective barriers as resorbable membranes has become a routine clinical procedure for guided bone regeneration. Therefore, the production of membranes with a low inflammatory potential during their resorption process has become the goal of a considerable number of researches. Aim:
The purpose of the present study was to evaluate the biocompatibility of poly (L- lactic acid) (PLLA) and biocelulose membranes (BC) inserted in the subcutaneous tissue on the dorsum of rats.Methods:
Fifteen animals underwent surgical procedures for the insertion of 4 types of membranes COL (Collagen membrane) Control Group; BC (Biocellulose membrane); BCAg (Biocellulose membrane impregnated with Silver); PLLA (Poly (L-lactic acid) membrane). All membrane types were inserted into each animal. Animals were euthanized after 3, 7, and 15 days of the surgical procedure. Descriptive histological analyses were carried out to investigate host tissue reaction to membrane presence by assessing the anti-inflammatory process composition associated with the membrane resorption and the presence of foreign-body reaction or encapsulation.Results:
The BC membranes showed a higher degree of inflammation and poor pattern of integration with the surrounding tissues than the PLLA and COL membranes.Conclusion:
The PLLA and COL membranes present better biocompatibility than the BC membranesPalavras-chave
Texto completo:
1
Bases de dados:
LILACS
Assunto principal:
Materiais Biocompatíveis
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Regeneração Óssea
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Teste de Materiais
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Ácido Láctico
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Tela Subcutânea
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Membranas
Limite:
Animals
Idioma:
En
Revista:
Braz. j. oral sci
/
Brazilian journal of oral sciences (Impresso)
/
Brazilian journal of oral sciences (Online)
Assunto da revista:
ODONTOLOGIA
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Brasil