Short term histopathological effects of GaAlAs laser on experimentally induced TMJ osteoarthritis in rabbits
Braz. oral res. (Online)
; 32: e90, 2018. tab, graf
Article
em En
| LILACS
| ID: biblio-952149
Biblioteca responsável:
BR1.1
ABSTRACT
Abstract The aim of this study was to evaluate the biostimulation (BS) effect of the gallium-aluminum-arsenide (GaAlAs) diode laser by histopathology with an experimental osteoarthritis (OA) model in the temporomandibular joints (TMJ) of rabbits, in the early period. GaAlAs diode laser is used for pain reduction in TMJ disorders. Twenty-four adult male New Zealand white rabbits were randomly divided into three equal groups Control Group (CG), Study Group 1 (SG-1), and Study Group 2 (SG-2). Mono-iodoacetate (MIA) was administered to the right TMJs of all rabbits. The rabbits did not undergo any treatment for four weeks to allow the development of osteoarthritis. In SG-1, laser BS was applied to the rabbits at 940 nm, 5 W, and 15 J/cm2 in continuous wave mode at 48-hour intervals for 14 sessions; and in SG-2, laser BS was applied with the same parameters at 24-hour intervals for 28 sessions. Laser BS was not applied to the rabbits in CG. All rabbits were sacrificed simultaneously. The TMJ cartilage, osteochondral junction, chondrocyte appearance, and subchondral ossification were evaluated histopathologically. There was no statistically significant difference between the groups in terms of cartilage, osteochondral junction, chondrocyte appearance, and subchondral ossification values (p > 0.05). The laser BS protocol used in the study had no positive histopathological effects on TMJ OA in the early period.
Palavras-chave
Texto completo:
1
Bases de dados:
LILACS
Assunto principal:
Osteoartrite
/
Transtornos da Articulação Temporomandibular
/
Terapia com Luz de Baixa Intensidade
/
Lasers Semicondutores
Tipo de estudo:
Evaluation_studies
/
Guideline
/
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Braz. oral res. (Online)
Assunto da revista:
ODONTOLOGIA
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Turquia