Effects of different periods of gastric ischemia on liver as a remote organ
Acta cir. bras
; 33(11): 964-974, Nov. 2018. tab, graf
Article
em En
| LILACS
| ID: biblio-973473
Biblioteca responsável:
BR1.1
ABSTRACT
Abstract Purpose:
To evaluate the hepatic changes associated with gastric ischemia.Methods:
Thirty male rabbits were studied, distributed in 3 groups (n=10). Group 1 ligature and section of the gastric vasculature and removal of the liver after three hours; Group 2 ligature and section of the gastric vasculature and removal of the liver after 6 hours; Group 3 ligature and section of the gastric vasculature and removal of the liver after 12 hours. Blood samples were collected immediately before surgery and after the determined time of ischemia in each group to evaluate the hepatic function. After the death of the rabbits, the liver was removed for macro and microscopic study.Results:
An increase in aminotransferases and bilirubin occurred in groups 2 and 3. Total protein and albumin diminished in all of the animals. All of the rabbits from groups 2 and 3 presented hepatocellular necrosis.Conclusion:
The devascularization of the stomach for a period of above three hours is associated with hepatic morphological and functional disorders.Palavras-chave
Texto completo:
1
Bases de dados:
LILACS
Assunto principal:
Estômago
/
Isquemia
/
Fígado
Tipo de estudo:
Etiology_studies
Limite:
Animals
Idioma:
En
Revista:
Acta cir. bras
Assunto da revista:
CIRURGIA GERAL
/
Procedimentos Cir£rgicos Operat¢rios
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Brasil