Central hemodynamic parameters to predict cardiovascular outcomes and mortality among the elderly: protocol for a systematic review
São Paulo med. j
; 136(6): 501-504, Nov.-Dec. 2018.
Article
em En
| LILACS
| ID: biblio-991689
Biblioteca responsável:
BR1.1
ABSTRACT
ABSTRACT BACKGROUND:
Central blood pressure is a factor that may predict cardiovascular events. However, its use in clinical practice is not well consolidated. Therefore, the aim of our study will be to summarize the use of central hemodynamic parameters to predict cardiovascular-related outcomes and all-cause mortality. DESIGN ANDSETTING:
Protocol for systematic review of longitudinal observational studies conducted in healthcare institutions, as presented in the studies included.METHODS:
We will perform a systematic search in the electronic databases MEDLINE (via PubMed), EMBASE and LILACS (via Virtual Health Library (VHL)), using health descriptors terms for elderly people and for hemodynamic indices of central blood pressure. We will include articles that evaluated hemodynamic indices and at least one of the followingoutcomes:
all-cause mortality, total cardiovascular death, total non-cardiovascular death, myocardial infarction, stroke, coronary artery restenosis after percutaneous coronary intervention, revascularization and aortic syndromes. Two independent reviewers will conduct analysis on the abstracts selected and on the full-text articles. Two reviewers will independently perform data extraction and evaluate the methodological quality of the articles selected, and a third reviewer will evaluate any divergences. The methodological quality of the studies will be assessed in accordance with the ROBINS-I tool (Risk Of Bias In Non-randomized Studies of Interventions). RESULTS ANDCONCLUSIONS:
Through this systematic review, we intend to summarize evidence that supports the use of central hemodynamic parameters for central blood pressure to diagnose and perform prognostics on arterial hypertension in elderly patients within clinical practice and predict future cardiovascular events in this population. REGISTRATION Prospero - CRD42018085264.Palavras-chave
Texto completo:
1
Bases de dados:
LILACS
Assunto principal:
Revisões Sistemáticas como Assunto
/
Hemodinâmica
/
Hipertensão
/
Infarto do Miocárdio
Tipo de estudo:
Clinical_trials
/
Guideline
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Systematic_reviews
Limite:
Aged
/
Humans
Idioma:
En
Revista:
São Paulo med. j
Assunto da revista:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
MEDICINA
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Brasil