Total IgE plasma levels vary according to gender and age in Brazilian patients with allergic rhinitis
Clinics
; 69(11): 740-744, 11/2014. tab
Article
em En
| LILACS
| ID: lil-731103
Biblioteca responsável:
BR1.1
ABSTRACT
OBJECTIVE:
Allergic rhinitis is a disease that affects the upper airways and causes inflammation of the nasal mucosa and it is mediated by IgE antibodies produced after sensitization to environmental allergens. Previous reports have indicated that this disease affects males more often than females. The objective of this study was to verify whether total IgE plasma levels vary between genders in patients suffering from allergic rhinitis.METHODS:
A total of 171 adult patients suffering from allergic rhinitis (55 males and 116 females) were enrolled. Total IgE plasma levels were determined using commercial kits, with 140 IU/mL considered as a reference value. The mean total IgE plasma levels were compared according to gender and age.RESULTS:
The mean age of the overall patient group with allergic rhinitis was 38.4±19.0 years and a significant difference in age was observed between genders (males 32.2±17.8 years; females 41.4±18.9 years; p = 0.0027). Additionally, the mean total IgE plasma levels were higher in males (413.0±143.0 IU/mL) than in females (147.9±98.0 IU/mL) (p<0.0001). These differences persisted even when males and females were stratified by age (up to or older than 20 years of age).CONCLUSIONS:
In conclusion, total IgE plasma levels are higher in young adult males than in females suffering from allergic rhinitis. Evaluating total IgE plasma levels can be useful to identify patients at risk of allergic rhinitis in areas with low industrial pollution. .Palavras-chave
Texto completo:
1
Bases de dados:
LILACS
Assunto principal:
Imunoglobulina E
/
Rinite Alérgica
Tipo de estudo:
Prognostic_studies
Limite:
Adolescent
/
Adult
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Aged
/
Female
/
Humans
/
Male
País/Região como assunto:
America do sul
/
Brasil
Idioma:
En
Revista:
Clinics
Assunto da revista:
MEDICINA
Ano de publicação:
2014
Tipo de documento:
Article
/
Project document
País de afiliação:
Brasil