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1.
G Ital Oncol ; 9(4): 129-34, 1989.
Artículo en Italiano | MEDLINE | ID: mdl-2613282

RESUMEN

Ex novo Kaposi's Sarcoma 4 months after renal transplantation in a young patient is described. Progression of the tumoral lesions has been observed during combined immunosuppressive treatment with Prednisone, Azathioprine and Cyclosporin. Stopping Azathioprine and Cyclosporin as well as reducing Prednisone prevented new lesions and made the preexistent skin lesions less extensive. Clinical case, possible pathogenesis and therapeutic strategies are discussed.


Asunto(s)
Inmunosupresores/efectos adversos , Trasplante de Riñón , Sarcoma de Kaposi/inducido químicamente , Neoplasias Cutáneas/inducido químicamente , Adulto , Humanos , Masculino , Sarcoma de Kaposi/patología , Neoplasias Cutáneas/patología
2.
Drugs Exp Clin Res ; 12(8): 707-11, 1986.
Artículo en Inglés | MEDLINE | ID: mdl-3757765

RESUMEN

The effects of chronic administration of L-carnitine were evaluated by EMG analysis in 20 uraemic patients undergoing periodical haemodialysis (mean duration of dialysis 34.7 months). No important changes in motor conduction velocity or distal latency of the external popliteal nerve were found after the treatment, while a reduction in the number of polyphasic muscle action potentials was observed. After carnitine administration, an increase of total EMG power was noted and the spectral array showed a progressive shift towards lower frequencies in 8 patients who had shown higher values. These results suggest that carnitine has a prevalent "myotrophic" effect.


Asunto(s)
Carnitina/farmacología , Fallo Renal Crónico/fisiopatología , Músculos/efectos de los fármacos , Adulto , Computadores , Electromiografía , Potenciales Evocados/efectos de los fármacos , Femenino , Humanos , Fallo Renal Crónico/terapia , Masculino , Persona de Mediana Edad , Contracción Muscular/efectos de los fármacos , Músculos/fisiopatología , Diálisis Renal , Uremia/metabolismo , Uremia/fisiopatología
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