RESUMEN
Further investigation of different fractions from Lotus polyphyllos Clarke roots resulted in the isolation of the new 3-arylcoumarin derivative; 4',6'-dihydroxy-7, 2'-dimethoxy-3-arylcoumarin (5). In addition, the known compounds beta-sitosterol, 1-hexacosanol (1), n-tetracosyl p-coumarate (2), 4'-O-methylderrone (4), and quercetin (6) were identified. The structures were determined from spectroscopic data including 1D- and 2D-NMR experiments.
Asunto(s)
Cumarinas/aislamiento & purificación , Lotus/química , Cumarinas/química , Resonancia Magnética Nuclear Biomolecular , Raíces de Plantas/química , Espectrometría de Masa Bombardeada por Átomos Veloces , Espectrofotometría UltravioletaRESUMEN
Investigation of the roots of Lotus polyphyllos Clarke resulted in the isolation of two new isoflavone derivatives; 4'-O-methylerythrinin C (3) and 4'-O-methyl-2''-hydroxydihydroalpinumisoflavone (4). In addition, the three known isoflavone derivatives 4'-O-methylalpinumisoflavone (1) lupinalbin F (5), 4',7-dimethoxy-5-hydroxyisoflavone (6), and the phenylpropanoid ester tetracosyl p-coumarate (2) were also identified. The structures were determined from spectroscopic data.
Asunto(s)
Isoflavonas/aislamiento & purificación , Lotus/química , Egipto , Isoflavonas/química , Espectrometría de Masas , Estructura Molecular , Resonancia Magnética Nuclear Biomolecular , Raíces de Plantas/química , Espectrofotometría UltravioletaRESUMEN
Two new alkaloids; ent-6alpha/6beta-hydroxybuphanisine, (-)-8-demethylmaritidine and seven known alkaloids were isolated from Pancratium sickenbergeri grown in Egypt. Three of the known alkaloids were tested in the NCI cytotoxicity screen, but were found to be inactive.