1.
Bone Marrow Transplant
; 54(12): 1923-1925, 2019 12.
Artículo
en Inglés
| MEDLINE
| ID: mdl-30890768
Asunto(s)
Antineoplásicos Alquilantes/efectos adversos , Clorhidrato de Bendamustina/efectos adversos , Riñón/efectos de los fármacos , Linfoma/tratamiento farmacológico , Mieloma Múltiple/tratamiento farmacológico , Antineoplásicos Alquilantes/farmacología , Antineoplásicos Alquilantes/uso terapéutico , Clorhidrato de Bendamustina/farmacología , Clorhidrato de Bendamustina/uso terapéutico , Femenino , Humanos , Incidencia , Masculino
2.
A A Pract
; 12(4): 96-98, 2019 Feb 15.
Artículo
en Inglés
| MEDLINE
| ID: mdl-30052534
RESUMEN
We present a case of a 73-year-old cancer patient with low transcutaneous oxygen saturation who was transferred to the intensive care unit after deployment of the rapid response team. Differential diagnosis remained broad until methemoglobinemia (MetHb) was detected.MetHb was induced by administration of rasburicase, which was given to prevent tumor lysis syndrome. In a follow-up examination, glucose-6-phosphate dehydrogenase deficiency was found to be the cause of MetHb after rasburicase exposure.Diagnosis was made by either measuring arterial MetHb or CO oximeter. Treatment options involve transfusion and methylene blue, if glucose-6-phosphate dehydrogenase deficiency is not present.