Biliothorax in a Siamese cat.

A 2-year-old male neutered cat presented for further investigation of biliothorax. The cat was initially treated for pyothorax, including bilateral chest drains for lavage of the pleural space. Five days later, the pleural effusion turned clear-yellow and had a bilirubin concentration of 427 µmol/l compared to the serum bilirubin concentration of 15 µmol/l. Exploratory surgery revealed a 2mm tear in the diaphragm, with a corresponding 2mm defect in the diaphragmatic surface of the gall bladder, creating a fistula between the gall bladder and the pleural cavity. The defects were repaired routinely and the cat made a full recovery. It was suspected that the tears had been created at the time of the thoracostomy tube placement. Biliothorax has not been described before in a cat, and appears to be a rare complication following thoracostomy tube placement.

Use of recombinant human interferon alpha-2a in the management of a dog with epitheliotropic lymphoma.

An 8-year-old, mixed-breed dog with preputial epitheliotropic lymphoma was initially treated with cyclophosphamide, vincristine, and prednisolone. A short-term partial response was followed by disease progression after 4 weeks. Recombinant human interferon alpha-2a was administered starting at week 7. The interferon therapy resulted in rapid resolution of clinical signs and a 10-week disease-free interval. The lymphoma recurred at 17 weeks and did not respond to rescue chemotherapy. Additional oral lesions were treated with localized radiotherapy followed by increased dosages of interferon. This additional interferon treatment resulted in another 12 weeks of stable disease.

Efficacy of en bloc ligation of the thoracic duct: descriptive study in 14 dogs.

OBJECTIVE: To assess whether en bloc ligation of all caudal mediastinal tissue between the aorta and thoracic vertebrae will occlude all branches of the thoracic duct. STUDY DESIGN: Descriptive study. ANIMALS: Canine cadavers (n=15). METHODS: The cisterna chyli was approached through a right paralumbar abdominal incision and cannulated. A right 10th intercostal thoracotomy was performed and the tissue of the caudal mediastinum dorsal to the aorta and ventral to the thoracic vertebrae was ligated. Radio-opaque contrast material was injected into the cisterna chyli during fluoroscopic imaging of the thorax and cranial abdomen. Still images were obtained before and after contrast injection and a subtraction image produced. Gray values were measured from these images, cranial and caudal to the ligature site. RESULTS: Cannulation of the cisterna chyli in 1 cadaver was impossible and it was, therefore, excluded. In 13 (93%) cadavers contrast material did not pass cranial to the ligature site. In 1 cadaver, an intact thoracic duct was identified on lymphangiography outside the en bloc ligation. CONCLUSION: En bloc ligation of the caudal mediastinal tissue dorsal to the aorta was successful in preventing opacification with contrast material of all branches of the thoracic duct in 93% of cadavers. CLINICAL RELEVANCE: En bloc ligation is successful in 93% of cadavers and reduces the operative time compared with techniques requiring some type of mesenteric lymphangiography to aid identification of the thoracic duct.