Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 32
Filtrar
1.
Tech Coloproctol ; 21(2): 149-153, 2017 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-28108825

RESUMEN

BACKGROUND: Photodynamic therapy (PDT) is a new procedure for the treatment of anal fistula. This preliminary study was designed to investigate the safety and effectiveness of this new technique in the treatment of anal fistula. METHODS: Ten patients were treated with PDT. Intralesional 5-aminolevulinic acid (ALA) 2% was directly injected into the fistula. The internal and external orifices were closed. After an incubation period of 2 h, the fistula was irradiated using an optical fibre connected to a red laser (MULTIDIODE 630 PDT, INTERmedic, Spain) operating at 1 W/cm for 3 min (180 Joules). Patient demographics, operation notes and complications were recorded. RESULTS: There were no complications. The average length of patient follow-up was 14.9 months (range 12-20 months). We could observe primary healing in eight patients (80%). Two patients (20%) showed persistence of suppuration after the operation. No patient reported incontinence postoperatively. CONCLUSIONS: PDT is a potential sphincter-saving procedure that is safe, simple and minimally invasive and has a high success rate.


Asunto(s)
Ácido Aminolevulínico/administración & dosificación , Terapia por Láser/métodos , Fotoquimioterapia/métodos , Fármacos Fotosensibilizantes/administración & dosificación , Fístula Rectal/tratamiento farmacológico , Adolescente , Adulto , Anciano , Antiinfecciosos/administración & dosificación , Profilaxis Antibiótica/métodos , Terapia Combinada , Femenino , Estudios de Seguimiento , Humanos , Inyecciones , Masculino , Metronidazol/administración & dosificación , Persona de Mediana Edad , Tobramicina/administración & dosificación , Resultado del Tratamiento , Adulto Joven
2.
Int J Colorectal Dis ; 31(2): 197-210, 2016 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-26507962

RESUMEN

PURPOSE: To obtain a prognostic index, which has been named PROCOLE (prognostic colorectal leakage), it can predict the risk that a certain individual may suffer anastomotic leakage. METHODS: The methodology consists of a systematic review to identify potential risk factors for anastomotic leakage and a meta-analysis of studies of each of these factors. In the meta-analysis, the prognostic index integrates factors that are statistically significant, which are weighted according to the estimated value of the effect size. The prognostic index was validated using retrospectively collected data from patients who underwent colorectal cancer surgery anastomosis at our institution. RESULTS: The mean and standard deviation of the PROCOLE prognostic index in patients with anastomotic leakage is 1.9 ± 6.13, whereas in controls, it is 3.63 ± 2.1. The predictive ability of the PROCOLE, assessed by calculating the area under the curve (AUC) of the receiver operating characteristic (ROC), results in an AUC of 0.82 with a 95% confidence interval (CI) (0.75, 0.89) of the AUC, and it can be considered a good prognostic indicator. CONCLUSIONS: The PROCOLE prognostic index predicts the risk of a certain individual developing anastomotic leakage after colorectal cancer surgery. Specifically, the PROCOLE prognostic index establishes a discrimination value threshold of 4.83 for recommending the implementation of a protective stoma. We have developed free software with a simple interface that only requires the selection of risk factors to obtain the PROCOLE value.


Asunto(s)
Fuga Anastomótica/etiología , Colon/cirugía , Neoplasias Colorrectales/cirugía , Recto/cirugía , Humanos , Estudios Observacionales como Asunto , Pronóstico , Factores de Riesgo
3.
Rev. chil. cir ; 67(3): 259-264, jun. 2015. graf
Artículo en Español | LILACS | ID: lil-747498

RESUMEN

Objective: The rupture of mammary protheses PIP (poly-implant-prothese) caused an alarm, settling in Spain a protocol for the management of patients. As hospital unit of reference for the management, monitoring and treatment of patients carrying PIP breast implants, we propose objective to make a descriptive study of the current situation in our country and compare it to the hitherto described in the literature. Method: We conducted a transversal study of all patients who came during the years 2012 and 2013, to the Unit of Mammary Pathology of the Universitary General Hospital of Elche. Results: With a total of 285 women, we observed a high rate of implant rupture (50.2 percent) asymptomatic most (84.6 percent). Fact that the year 2006 had the highest percentage of breakage and the appearance of siliconomas. Conclusions: Our series confirms rupture rate similar to that described in the literature for PIP breast implants. We observed a higher percentage of breakage from the year 2006, coinciding with the period of manufacture described poorer quality of these implants. Axillary siliconomas were evident in 35.1 percent of patients, the only locally axillary symptoms.


Objetivo: La rotura de las prótesis mamarias PIP (poly-implant-prothese) ha supuesto una alarma, estableciéndose en España un protocolo para el manejo y seguimiento de las pacientes. Como unidad hospitalaria de referencia para el manejo, seguimiento y tratamiento de las pacientes portadoras de prótesis mamarias PIP, nos proponemos como objetivo realizar un estudio descriptivo de la situación actual en nuestro medio y compararlo con lo hasta ahora descrito en la literatura. Método: Realizamos un estudio transversal de todas las pacientes que acudieron durante los años 2012 y 2013, a la Consulta de la Unidad de Patología Mamaria del Hospital General Universitario de Elche. Resultados: Con un total de 285 mujeres, observamos la elevada tasa de ruptura de los implantes (50,2 por ciento) la mayoría asintomáticos (84,6 por ciento). Siendo el año 2006 el de mayor porcentaje de rotura y la aparición de siliconomas. Conclusiones: Se confirma una tasa de ruptura similar a la descrita en la literatura para los implantes mamarios PIP. Observamos un mayor porcentaje de rotura a partir del año 2006, coincidiendo con el período de fabricación descrito de peor calidad de estos implantes. Se evidenciaron siliconomas axilares en el 35,1 por ciento de las pacientes, siendo la única sintomatología a nivel local axilar.


Asunto(s)
Humanos , Adulto , Femenino , Persona de Mediana Edad , Implantación de Mama/métodos , Implantes de Mama/efectos adversos , Implantes de Mama/estadística & datos numéricos , Falla de Prótesis , Estudios Transversales , Complicaciones Posoperatorias/epidemiología , Remoción de Dispositivos , Estudios de Seguimiento , Geles de Silicona/efectos adversos , Implantación de Prótesis/efectos adversos , Rotura
4.
J Gastrointest Surg ; 19(5): 813-20, 2015 May.
Artículo en Inglés | MEDLINE | ID: mdl-25560183

RESUMEN

BACKGROUND: The lymph node ratio (LNR) and log odds of positive lymph nodes (LODDS) have been proposed to minimize the stage migration phenomenon. The value of the LODDS and LNR staging systems to predict and discriminate prognosis was assessed and compared to the International Union Against Cancer (UICC) TNM classification (pN). METHODS: Three hundred and twenty-six patients with gastric carcinoma were retrospectively studied. Disease-specific survival rates were calculated for every pN, LNR, and LODDS category. RESULTS: Four LNR categories (0, 1-25, 26-75, and >76 %) and four LODDS categories (-5 to -3, > -3 to -1, > -1 to 3, and >3 to 5) were established. In the multivariate analysis, only the stage pT3-4 versus pT1-2 (HR 1.88, 95 % CI 1.11-3.20, p=0.02) and LODDS as continuous variable (HR 1.40, 95 % CI 1.21-1.61, p<0.001) remained as independent prognostic factors. In patients with <16 lymph nodes retrieved, only the LODDS system could discriminate different disease-specific survival curves for every category. LODDS categories were able to discriminate subgroups with different prognoses in pN stages and LNR categories. CONCLUSIONS: The LODDS staging system was superior to the pN classification and LNR system to discriminate risk prognosis especially in patients with an insufficient number of retrieved lymph nodes.


Asunto(s)
Ganglios Linfáticos/patología , Estadificación de Neoplasias , Neoplasias Gástricas/diagnóstico , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Gastrectomía , Humanos , Masculino , Persona de Mediana Edad , Pronóstico , Estudios Retrospectivos , Neoplasias Gástricas/cirugía , Tasa de Supervivencia
5.
Eur J Surg Oncol ; 40(3): 358-65, 2014 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-24075824

RESUMEN

BACKGROUND: The optimal system for lymph node (LN) staging in gastric cancer is still a subject of debate. The aim of our study was to analyse the probability of error in negative LN (pN0) gastric carcinomas when a low number of LNs were harvested using a probabilistic model. METHODS: Patients with gastric carcinoma who underwent R0 resection at three university hospitals between 2004 and 2009 were retrospectively included. A Bayesian model was used to analyse the probability of error for negative LNs (pN0) gastric carcinomas. Kaplan-Meier survival curves and the log-rank test were used to compare the overall and specific mortality of prognosis groups. RESULTS: Of the 291 patients included, 123 were classified as pN0 (42%). A significant correlation was found between the extent of the LN dissection performed and the number of the LNs retrieved. According to the Bayesian model the carcinomas with 9 or fewer negative lymph nodes were considered to have a high risk (HR) of misclassification, whereas patients with 10-25 LNs analysed and those with more than 26 negative lymph nodes were considered to have a moderate risk (MR) and low risk (LR), respectively. The log-rank test showed a significant improvement in the disease-specific survival for the MR pN0 (p < 0.001) and LR pN0 (p < 0.04) but not for the HR pN0 patients compared to pN1 patients. CONCLUSIONS: The proposed probabilistic model is clinically useful for differentiating the prognosis in pN0 gastric carcinomas when an insufficient number of negative lymph nodes are retrieved.


Asunto(s)
Adenocarcinoma/mortalidad , Adenocarcinoma/secundario , Ganglios Linfáticos/patología , Neoplasias Gástricas/mortalidad , Neoplasias Gástricas/patología , Adenocarcinoma/cirugía , Adulto , Anciano , Anciano de 80 o más Años , Teorema de Bayes , Estudios de Cohortes , Supervivencia sin Enfermedad , Femenino , Gastrectomía/métodos , Gastrectomía/mortalidad , Humanos , Estimación de Kaplan-Meier , Escisión del Ganglio Linfático/métodos , Ganglios Linfáticos/cirugía , Metástasis Linfática , Masculino , Persona de Mediana Edad , Análisis Multivariante , Invasividad Neoplásica/patología , Estadificación de Neoplasias , Pronóstico , Estudios Retrospectivos , Medición de Riesgo , España , Estadísticas no Paramétricas , Neoplasias Gástricas/cirugía , Análisis de Supervivencia , Resultado del Tratamiento
6.
Rev. chil. cir ; 65(5): 409-414, set. 2013. tab
Artículo en Español | LILACS | ID: lil-688446

RESUMEN

Introduction: axillary lymph node dissection (ALND) is still a usual procedure in the treatment of breast cancer. A drain is normally placed in the surgical bed and maintained several days until obtaining a daily discharge of 30-50 ml, in order to reduce the appearance of seroma. The aim of this study was to analyze possible factors associated with an increased drainage volume. Patients and Methods: a retrospective study of all the patients undergoing ALND for breasts cancer at our institution between 2011 and 2012 was performed. Results: 40 females were included. There were no complications or mortality. Median hospital stay was 2 days. Median day of drainage removal was the 5th postoperative day. Mean total drainage volume was 298.9 +/- 240.1 ml. High blood pressure associated with an increased drainage volume (550 ml vs 217.5 ml; p = 0.001) and a later removal (8th vs 4th day; p = 0.002). Similar happened with age > 65 years (420.8 ml vs 24.6 ml; p = 0.003) and (7th vs 5th day; p = 0.009). The number of metastatic lymph nodes showed a direct correlation with total drainage volume (Pearson 0.503; p = 0.017) and removal day (Spearman 0.563; p = 0.006), similar to the primary tumour size: total drainage volume (Pearson 0.447; p = 0.042) and removal day (Spearman 0.556; p = 0.009). Conclusion: age over 65 years, high blood pressure, number of metastatic lymph nodes and primary tumour size associated with a higher drainage volume and time to remove the drain.


Introducción: la linfadenectomía axilar (LA) sigue siendo un procedimiento frecuente en el tratamiento del cáncer de mama. Habitualmente se coloca un drenaje en el hueco axilar, que se mantiene varios días, hasta que tiene un débito diario de 30-50 ml, con el fin de reducir la aparición de seroma. El objetivo del presente estudio es analizar posibles factores asociados a un mayor volumen de drenaje. Pacientes y Métodos: realizamos un estudio retrospectivo de todas las pacientes intervenidas de LA por cáncer de mama en nuestro centro durante los años 2011 y 2012. Resultados: incluimos 40 mujeres en el estudio. No hubo complicaciones ni mortalidad. La mediana de estancia hospitalaria fue de 2 días. El día mediano de retirada de drenaje fue el 5° postoperatorio. El volumen medio total del drenaje fue 298,9 +/- 240,1 ml. La hipertensión arterial se asocia a un mayor volumen de drenaje (550 ml vs 217,5 ml; p = 0,001) y a una retirada más tardía del mismo (8° día vs 4° día; p = 0,002). Al igual ocurre con la edad > 65 años (420,8 ml vs 24,6 ml; p = 0,003) y (7° vs 5° día; p = 0,009). El número de ganglios metastásicos también se correlaciona con el volumen total de drenaje (coeficiente de correlación de Pearson 0,503; p = 0,017) y con el día de retirada (Spearman 0,563; p = 0,006), lo mismo que el tamaño del tumor primario: volumen total de drenaje (Pearson 0,447; p = 0,042) y día de retirada (Spearman 0,556; p = 0,009). Conclusión: la edad mayor de 65 años, la hipertensión arterial, el número de ganglios metastásicos y el tamaño del tumor primario se asocian con mayor volumen por el drenaje axilar y días necesarios hasta la retirada.


Asunto(s)
Humanos , Femenino , Adulto , Persona de Mediana Edad , Drenaje , Escisión del Ganglio Linfático/efectos adversos , Escisión del Ganglio Linfático/métodos , Neoplasias de la Mama/cirugía , Axila , Complicaciones Posoperatorias/prevención & control , Hipertensión/complicaciones , Mastectomía , Análisis Multivariante , Estudios Retrospectivos , Factores de Riesgo , Seroma/etiología , Seroma/prevención & control
7.
Rev. chil. cir ; 65(5): 421-428, set. 2013. tab
Artículo en Español | LILACS | ID: lil-688448

RESUMEN

Objective: to evaluate the complications of sacral nerve stimulation for the treatment of fecal incontinence. Background: sacral nerve stimulation is considered to be nowadays an effective treatment for fecal incontinence in selected patients. Many authors have reported excellent results and indication for his use have increased. Nevertheless, even being a simple technique, not it exempts this from complications. Methods: fifty-two patients with severe faecal incontinence, treated with sacral nerve stimulation between january 2002 and december 2010, were analysed. All adverse events during follow-up were recorded. Results: there was not surgical complication during peripheral neural evaluation test. In our series, with an average follow-up to 55.52 +/- 31.84 months (range: 12-121), we had a rate of adverse effects of 14 percent, infection of surgical wound in two patients, break of electrode in two patients and the presence of pain in the place of the implant, with episodes of extremity pain and paresthesias in low members in 3 patients. Conclusions: sacral nerve stimulation in severe fecal incontinence is a safe treatment, with a low index of complications.


Objetivo: evaluar las complicaciones de la neuromodulación de raíces sacras en el tratamiento de la incontinencia fecal. Introducción: la neuromodulación de raíces sacras ha sido descrita como un tratamiento quirúrgico eficaz en pacientes con incontinencia fecal grave. Muchos autores han comunicado excelentes resultados y las indicaciones en su uso han aumentado. Sin embargo, a pesar de ser una técnica quirúrgica sencilla, no está exenta de complicaciones. Material y Método: 52 pacientes con incontinencia fecal grave, tratados mediante neuromodulación de raíces sacras entre enero de 2002 y diciembre de 2010, fueron analizados. Todas las complicaciones, tanto durante la implantación del dispositivo como durante el seguimiento, fueron registradas. Resultados: no se registraron complicaciones durante la prueba de estimulación. En nuestra serie, con un seguimiento de 55,52 +/- 31,84 meses, observamos un 14 por ciento de efectos adversos, infección de la herida quirúrgica en dos pacientes, rotura o movilización del electrodo en 2 pacientes y dolor y parestesias en 3 pacientes. Discusión: la neuroestimulación de raíces sacras en el tratamiento de la incontinencia fecal es un tratamiento seguro, con un bajo índice de complicaciones.


Asunto(s)
Humanos , Masculino , Femenino , Adulto , Persona de Mediana Edad , Incontinencia Fecal/terapia , Terapia por Estimulación Eléctrica/efectos adversos , Estudios de Seguimiento , Neuroestimuladores Implantables , Incontinencia Fecal/cirugía , Incontinencia Fecal/complicaciones , Plexo Lumbosacro , Estudios Prospectivos
9.
Rev. chil. cir ; 64(5): 480-482, oct. 2012. ilus
Artículo en Español | LILACS | ID: lil-651879

RESUMEN

Background: The incidence of ileitis following ileostomy is 5 percent. Material and Method: We report a 79 years old male with a sigmoid cancer presenting with an intestinal obstruction. Results: Patient required a subtotal colectomy, leaving a terminal ileostomy in the right lower flank. Three days after the intervention, the patient had a profuse bleeding through the ileostomy. An emergency endoscopy showed multiple bleeding ulcers in the ileostomy. The patient did not respond to medical treatment and required a new intervention, excising 20 cm of distal ileum and performing a new ileostomy. The pathological study of the excised segment showed multiple superficial ulcers with abundant inflammatory cells.


Introducción: La ileitis tras ileostomía es una entidad poco frecuente, pero que conlleva una importante morbilidad. Objetivo: Describir un caso de ileitis postileostomía sin respuesta al tratamiento médico y revisar la literatura sobre el tema. Material y Método: Presentamos el caso de un varón de 79 años con sangrado agudo por ileostoma tras colectomía subtotal. Resultados: Tras fracaso de la terapia médica fue necesario realizar resección de segmento de íleon terminal afecto. Conclusiones: Se debe pensar en ileitis postileostomía en caso de ileostomías muy productivas o ileorragias y comenzar tratamiento esteroideo temprano y realizar ileoscopia precoz. La cirugía se reserva para aquellos casos en los que no es eficaz el tratamiento médico.


Asunto(s)
Humanos , Masculino , Anciano , Hemorragia , Ileítis/etiología , Ileostomía/efectos adversos , Complicaciones Posoperatorias/etiología
10.
Tech Coloproctol ; 16(4): 301-7, 2012 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-22706731

RESUMEN

BACKGROUND: In most cases of diverticulitis, inflammation is mild, and the only treatment required is a clear liquid diet and antibiotics. Until recently, patients were given this treatment as inpatients with the consequent expenditure of resources. The aim of this study was to assess the safety and efficacy of an outpatient treatment protocol with oral antibiotics in selected patients with uncomplicated acute diverticulitis in comparison with inpatient intravenous treatment. METHODS: We conducted a prospective non-randomized study between January 2007 and December 2009. We included all patients diagnosed with uncomplicated acute diverticulitis, at the Emergency Department of the University General Hospital of Elche. We compared the efficacy, safety and costs of hospital treatment with intravenous antibiotics and outpatient treatment with oral antibiotics. Seventy-six patients were included in the study. Forty-four of them underwent intravenous treatment with Metronidazole 500 mg/8 h + Ciprofloxacin 400 mg/12 h (hospital treatment group) and 32 took oral antibiotics Metronidazole 500 mg/8 h and Ciprofloxacin 500 mg/12 h (outpatient group). RESULTS: Outpatient treatment is viable in almost 95 % of those patients suffering from uncomplicated acute diverticulitis. Treatment was effective in resolving inflammation, and there were no complications in the majority of cases (94 %). Only 2 patients (6 %) required admission after outpatient treatment. The results further reflect complications and relapse rates similar to those of patients admitted to hospital and treated with intravenous antibiotics. There are no significant statistical differences (p = 0.86) between inpatients and outpatients. It is possible to save approximately 1,600 € per patient with outpatient treatment (p < 0.05). CONCLUSIONS: Outpatient treatment has demonstrated a safety and efficiency similar to inpatient treatment, producing an important reduction in expenses and medical resources.


Asunto(s)
Atención Ambulatoria , Antiinfecciosos/uso terapéutico , Ciprofloxacina/uso terapéutico , Diverticulitis/dietoterapia , Diverticulitis/tratamiento farmacológico , Metronidazol/uso terapéutico , Acetaminofén/administración & dosificación , Acetaminofén/uso terapéutico , Enfermedad Aguda , Adulto , Anciano , Anciano de 80 o más Años , Antiinfecciosos/administración & dosificación , Ciprofloxacina/administración & dosificación , Colonoscopía , Terapia Combinada , Femenino , Costos de Hospital , Humanos , Infusiones Intravenosas , Masculino , Metronidazol/administración & dosificación , Persona de Mediana Edad , Estudios Prospectivos , Resultado del Tratamiento
11.
Br J Surg ; 95(12): 1521-7, 2008 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-18942056

RESUMEN

BACKGROUND: This prospective multicentre study assessed the safety and effectiveness of stapled transanal rectal resection (STARR) for treatment of obstructive defaecation syndrome (ODS). METHODS: Between February 2001 and June 2006, 104 patients diagnosed with ODS were treated with STARR. Follow-up was scheduled for 1, 3 and 6 months after surgery, and annually thereafter. Variables related to the patient, surgical technique and outcome were analysed. RESULTS: Mean operating time was 46.7 min. Haemorrhage at the staple line occurred in 55 patients (52.9 per cent). Three patients required surgical revision in the first 48 h owing to persistent bleeding. The median postoperative pain score was 2.4 on a scale from 1 to 10. Mean hospital stay was 2.2 days. The mean constipation score improved from 13.5 before surgery to 5.1 at 1-year follow-up (P = 0.006). Twenty-three patients reported faecal incontinence at 4 weeks after surgery, but only nine still had minor residual incontinence by 1 year. At a median follow-up of 26 (range 12-72) months, ODS had recurred or persisted radiologically and/or clinically in 11 patients. CONCLUSION: STARR is associated with low morbidity and a short hospital stay, and is an effective alternative treatment for ODS.


Asunto(s)
Estreñimiento/cirugía , Incontinencia Fecal/cirugía , Obstrucción Intestinal/cirugía , Enfermedades del Recto/cirugía , Adulto , Anciano , Femenino , Hemorragia Gastrointestinal/etiología , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Enfermedades del Recto/etiología , Síndrome
14.
Histopathology ; 46(4): 389-95, 2005 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-15810950

RESUMEN

AIMS: To assess MRP1 protein and MRP1 mRNA levels in gastric carcinomas and in non-neoplastic mucosa remote from the tumours. MRP1 gene expression may play a role in the complex pattern of chemoresistance present in gastric carcinomas. METHODS AND RESULTS: A total of 57 carcinomas and respective gastric tissues were included for immunohistochemical assessment with the anti-MRP1 monoclonal antibodies MRPr1 and QCRL-1. Of these, 35 tumour and gastric mucosa tissues were also assessed by real-time quantitative reverse transcriptase-polymerase chain reaction. Medium or high MRP1 protein expression was detected in 89% and 77% of carcinomas and in 96% and 93% of non-neoplastic gastric mucosa by MRPr1and QCRL-1, respectively. No difference in MRP1 mRNA levels was detected between carcinomas and non-neoplastic gastric mucosa tissues in 77% of the patients. A significant correlation was found between MRP1 mRNA level and protein expression detected in carcinomas related to non-neoplastic gastric mucosa, although they were non-concordant in 29% of the patients. CONCLUSIONS: MRP1 gene is usually expressed in most gastric carcinomas and does not differ substantially from that observed in non-neoplastic gastric mucosa remote from the tumour. However, a decrease in MRP1 gene expression is found in some carcinomas. For accurate assessment of changes in MRP1 expression between tumour and normal tissues both protein and mRNA detection are necessary.


Asunto(s)
Proteínas Asociadas a Resistencia a Múltiples Medicamentos/genética , Neoplasias Gástricas/patología , Mucosa Gástrica/metabolismo , Regulación Neoplásica de la Expresión Génica , Humanos , Inmunohistoquímica , Proteínas Asociadas a Resistencia a Múltiples Medicamentos/análisis , Estadificación de Neoplasias , ARN Mensajero/genética , ARN Mensajero/metabolismo , Reacción en Cadena de la Polimerasa de Transcriptasa Inversa/métodos , Neoplasias Gástricas/genética , Neoplasias Gástricas/metabolismo
15.
Int J Colorectal Dis ; 19(4): 370-3, 2004 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-15170517

RESUMEN

BACKGROUND AND AIMS: Nowadays there is still controversy as to whether open or closed haemorrhoidectomy is the surgical treatment of choice for haemorrhoidal pathology. PATIENTS AND METHODS: We carried out a randomised prospective study in the Day Surgery Unit comparing 100 patients undergoing Milligan-Morgan haemorrhoidectomy (group A) versus 100 patients undergoing Ferguson haemorrhoidectomy (group B) for symptomatic haemorrhoids, in whom medical treatment or rubber band ligation had failed. RESULTS: Characteristics of the population were: mean age 43.5 years, with predominance of males, 123 vs. 77; 88% ASA I-II. CLINICAL PRESENTATION: 95% rectal bleeding; 87.5% third-fourth degree. The anaesthetic technique of choice was local anaesthesia plus sedation in 180 patients (90%). Length of surgery: 24 min (group A) and 30 min (group B) (p=n.s.). Resection of three haemorrhoidal cushions was done in 87.5% of cases. There were no re-operations or re-admissions after discharge. Symptomatic recurrence, stenosis and incontinence were not found during the follow-up of the first year. Postoperative pain during the first postoperative week was greater in the open haemorrhoidectomy group, but the difference was statistically significant (p<0.05) only during bowel movements. There was complete healing in 40% of the patients in group A and 90% of those in group B (p<0.05) after 1 month. After 1 year, the results and complications were similar in both groups (p=n.s.). CONCLUSIONS: Closed haemorrhoidectomy gives better results in terms of pain and healing than open haemorrhoidectomy, whereas recurrence and complications are similar after 1 year.


Asunto(s)
Procedimientos Quirúrgicos del Sistema Digestivo/métodos , Hemorroides/cirugía , Adulto , Atención Ambulatoria , Defecación/fisiología , Procedimientos Quirúrgicos del Sistema Digestivo/efectos adversos , Femenino , Humanos , Masculino , Dolor Postoperatorio/fisiopatología , Estudios Prospectivos , España , Dehiscencia de la Herida Operatoria/etiología , Resultado del Tratamiento , Cicatrización de Heridas/fisiología
16.
Hernia ; 6(4): 175-7, 2002 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-12424596

RESUMEN

Given the outstanding outcome that prosthetic repair has recently achieved in the repair of inguinal hernia, we wonder whether it should be implemented as the gold-standard technique for umbilical hernia repair. We report on 213 adult patients who underwent surgery for umbilical hernia at our Day Surgery Unit from June 1992 to January 1998. Criteria for exclusion included problematic social and family environment and ASA IV status. A polypropylene plug was placed in small umbilical defects, whereas large defects (> 3 cm in diameter) were repaired with a polypropylene mesh. The mean follow-up was 64 months. The mean age was 57.1 years, with females accounting for the majority (57.8%). Most patients (88.3%) were classified as ASA I-II. With regard to the hernia size, 143 patients (67.1%) presented with small defects (< 3 cm). The anaesthetic technique of choice was local plus sedation. Reported complications included seroma (5.6%), haematoma (2.3%), wound infection (1.4%), and intolerance to prosthesis (0.95%), the last causing recurrence. The overall recurrence rate at a mean follow-up of 64 months was 0.95%. Prosthetic umbilical hernia repair can safely be performed in adults, and the rate of recurrence in this study is low in comparison to primary tissue repair.


Asunto(s)
Hernia Umbilical/cirugía , Prótesis e Implantes , Mallas Quirúrgicas , Adolescente , Adulto , Anciano , Procedimientos Quirúrgicos Ambulatorios , Femenino , Humanos , Masculino , Persona de Mediana Edad , Polipropilenos
17.
Aten Primaria ; 28(6): 381-5, 2001 Oct 15.
Artículo en Español | MEDLINE | ID: mdl-11602117

RESUMEN

OBJECTIVE: To describe the results of a programme of direct referral of potential surgery patients between primary and specialist care, designed to lessen waiting-times.Design. Prospective, longitudinal and descriptive study. SETTING: Health Area N. masculine 19 (Valencian Health Service): Surgery Service of Elche Hospital and 6 Health Centres. PARTICIPANTS: Patients with pathologies that do not need special techniques for diagnosis except examination and who have a clear irrefutable indication of surgery without risk factors (ASA I-II).Intervention. The referral protocol consists of: a) diagnosis of pathology and pre-operative study in primary care (PC); b) appointment made by phone for the surgery clinic at the hospital, where diagnosis and pre-operative study are confirmed; c) referral and operation in the unit of non-hospital major surgery (UCMA); d) monitoring post-operation by the home hospitalisation unit (HHU) or preferably by the health centre, and e) check-up at the surgery clinic. Main measurements. The degree of agreement between PC and the specialist, assessment of the pre-operative study, and waiting time. RESULTS: 86 patients were referred (average age, 35; 76% male) by 28 doctors. The most common pathologies were hernia (36%), pilonidal sinus (23.2%) and miscellaneous (32.5%). There was general agreement in diagnosis in 90.7% of cases. 89.5% of patients brought the proper pre-operative study. Mean waiting time between the primary care consultation in the different procedures and the first hospital consultation was 19 days; with 44 more days elapsing till the surgical operation. CONCLUSIONS: This new programme is effective and economic, in that there is <> of patients, waiting time is reduced by over 7 months for pilonidal sinus and by over 2 years for hernia pathology, and the procedure can be used for a large number of patients, as the pathologies involved are very common.


Asunto(s)
Medicina , Atención Primaria de Salud , Derivación y Consulta/normas , Especialización , Procedimientos Quirúrgicos Operativos/estadística & datos numéricos , Adolescente , Adulto , Anciano , Citas y Horarios , Áreas de Influencia de Salud , Femenino , Humanos , Estudios Longitudinales , Masculino , Persona de Mediana Edad , Pautas de la Práctica en Medicina , Evaluación de Programas y Proyectos de Salud , Derivación y Consulta/organización & administración , España , Listas de Espera
18.
Br J Surg ; 88(10): 1321-3, 2001 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-11578284

RESUMEN

BACKGROUND: Prosthetic repair has become the standard method for inguinal hernia and has excellent results. The question remains of whether the mesh technique could also improve results for umbilical defects. METHODS: The study was a randomized clinical trial comparing herniorrhaphy (primary suture) with hernioplasty (polypropylene mesh or plug) in 200 adult patients with a primary umbilical hernia. Patients at high anaesthetic risk (American Society of Anesthesiologists (ASA) grade IV) or those who needed emergency surgery were excluded. The mean postoperative follow-up was 64 months. The population studied included 118 women and 82 men with a mean age at presentation of 57 years. Some 173 patients were ASA grade I-II and 27 were ASA III. The anaesthetic technique of choice was local anaesthetic infiltration plus sedation (98 per cent). RESULTS: There were no significant anaesthetic complications or surgical deaths. The mean duration of surgery was greater for mesh than for suture repair (45 versus 38 min). Rates of early complications such as seroma, haematoma or wound infection were similar in the two groups. The hernia recurrence rate was higher after suture repair (11 per cent) than after mesh repair (1 per cent) (P = 0.0015). CONCLUSION: Prosthetic repair could become the standard treatment for primary umbilical hernia in adults.


Asunto(s)
Hernia Umbilical/cirugía , Mallas Quirúrgicas , Técnicas de Sutura , Adolescente , Adulto , Anciano , Urgencias Médicas , Femenino , Estudios de Seguimiento , Humanos , Tiempo de Internación , Masculino , Persona de Mediana Edad , Poliésteres/uso terapéutico , Polipropilenos/uso terapéutico , Cuidados Posoperatorios , Complicaciones Posoperatorias/etiología , Recurrencia , Factores de Riesgo
19.
Ambul Surg ; 9(2): 73-75, 2001 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-11454484

RESUMEN

The steadily increasing use of prosthetic grafts in hernia repairs can be said to play down the classical approach for repairing groin hernia. We retrospectively report on 894 patients operated on for groin hernia at our out-patient surgery clinic from June 1992 to May 1998. Herniorraphy was widely performed (96.3%). The recurrence rate was of 1.6% (overall). For patients younger than 45 yr with no systemic concurrent disease, as few as 0.1% relapsed after a 58-month average follow-up. According to our results, ambulatory herniorraphy can provide an excellent degree of efficiency in selected young patients suffering from indirect unilateral primary groin hernia. Likewise, we regard the prosthetic repair as the gold standard technique in those patients with a weakened posterior inguinal wall.

SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA