The efficacy of Platelet and Leukocyte Rich Fibrin (L-PRF) in the healing process and bone repair in oral and maxillofacial surgeries: a systematic review.

INTRODUCTION: The search to optimize the healing and bone repair processes in oral and maxillofacial surgeries reflects the constant evolution in clinical practice, driven by the demand for increasingly satisfactory results and the need to minimize postoperative complications. OBJECTIVE: To evaluate the efficacy of Platelet and Leukocyte Rich Fibrin (L-PRF) in the healing and bone repair process in oral and maxillofacial surgeries. MATERIALS AND METHODS: The systematic review protocol for this study included the definition of the research question, the domain of the study, the databases searched, the search strategy, the inclusion and exclusion criteria, the types of studies to be included, the measures of effect, the methods for screening, data extraction and analysis, and the approach to data synthesis. Systematic literature searches were carried out on Cochrane databases, Web of Science, PubMed, ScienceDirect, Embase and Google Scholar. RESULTS: The strategic search in the databases identified 1,159 studies. After removing the duplicates with the Rayyan© software, 946 articles remained. Of these, 30 met the inclusion criteria. After careful evaluation based on the inclusion and exclusion criteria, 8 studies were considered highly relevant and included in the systematic review. CONCLUSION: Platelet and Leukocyte Rich Fibrin (L-PRF) has a positive effect on the healing process and bone repair in oral and maxillofacial surgeries.

External root resorption of second molars caused by impacted third molars: an observational study in panoramic radiographs / Reabsorção radicular externa de segundos molares ocasionadas por terceiros molares impactados: estudo observacional em radiografias panorâmicas

Objective: This research investigate the presence of external root resorption (ERR) in second molars caused by impacted third molars in panoramic radiographs, relating to the position of third molars according to classification of Winter, Pell and Gregory. Material and method: A cross-sectional, retrospective study using panoramic radiographs obtained from January 2014 to December 2015. The inclusion criterion was the presence of a second molar adjacent to an impacted third molar. Data were analyzed using descriptive and inferential statistics. Pearson's Chi-Square Test and Fisher's Exact Test (p≤0.05) were performed. Result: The sample consisted of 584 panoramic radiographs, 356 (60.95%) of women, and 228 (39.05%) of men, the mean age was 25.31 years. The prevalence of ERR was 12.5%, and the group of 14-24 year olds was the most affected (p = 0.46). The presence of ERR was statistically higher in the mandible (42.1%) with p=0.01. The ERR located in the cervical (57.1%) and medium (58.8%) thirds was proportionally higher in the teeth with B2 (p=0.02) and mesio-angular positions (p=0.26). Conclusion: The prevalence of ERR in second molars, caused by impacted third molars, was shown to be similar to results found in the literature, with no gender preference, this affects young patients, occurring frequently in mandible teeth, and presents greater severity in the cervical and middle thirds. The B2 and mesio-angular positions were more prone to ERR.

Objetivo: Esta pesquisa investigou a presença de reabsorção radicular externa (RRE) em segundos molares ocasionada pelos terceiros molares impactados em radiografias panorâmicas, relacionando com a posição dos terceiros de acordo com a classificação de Winter e de Pell e Gregory. Material e método: Um estudo transversal, retrospectivo, por meio de radiografias panorâmicas obtidas no período de janeiro de 2014 a dezembro de 2015. Adotou-se como critério de inclusão, a presença um segundo molar adjacente a um terceiro molar impactado. Os dados foram analisados por meio de estatística descritiva e inferencial. Foram realizados o Teste Qui-Quadrado de Pearson e Teste Exato de Fisher (p≤0,05). Resultado: A amostra foi composta por 584 radiografias panorâmicas, sendo 356 (60,95%) do gênero feminino e 228 (39,05%) do masculino, a média de idade foi de 25,31 anos. A prevalência de RRE foi de 12,5%, e a faixa etária de 14-24 anos foi mais acometida (p=0,46). A presença de RRE foi estatisticamente maior na mandíbula (42,1%) com p=0,01. As RRE localizadas nos terços cervical (57,1%) e médio (58,8%) foram proporcionalmente maiores nos dentes nas posições B2 (p=0,02), e mesioangular (p=0,26). Conclusão: A prevalência de RRE em segundos molares causada por terceiros impactados se mostrou estar de acordo com a média existente na literatura mundial, sem predileção por gênero, acometendo mais pacientes jovens, frequentemente ocorre nos dentes da mandíbula e apresenta um maior grau de severidade no terço cervical e médio. As posições B2 e mesioangular apresentaram maior propensão à RRE.