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1.
Artículo en Inglés | MEDLINE | ID: mdl-38110086

RESUMEN

Polymyalgia rheumatica (PMR) is an inflammatory joint disease that presents in patients older than 50 years with prolonged morning pain and stiffness in the shoulder and hip joints and neck. The lack of specific clinical findings, laboratory signs, biomarkers and established imaging methods makes it difficult to diagnose patients with this disease. 18F-FDG PET/CT is a functional imaging technique that is an established tool in oncology and has also proven useful in the field of inflammatory diseases. The aim of this paper is to present literature evidence on the use of molecular imaging methods such as PET/CT for early diagnosis, assessment of disease activity and therapeutic response in PMR. At the same time, the advantages, disadvantages and contraindications of other methods are considered.


Asunto(s)
Arteritis de Células Gigantes , Medicina Nuclear , Polimialgia Reumática , Humanos , Polimialgia Reumática/diagnóstico por imagen , Tomografía Computarizada por Tomografía de Emisión de Positrones , Fluorodesoxiglucosa F18
2.
Artículo en Inglés | MEDLINE | ID: mdl-36195256

RESUMEN

A diagnosis of cancer is frightening at any age, but especially when the patient is a child. Only what is suspected can be diagnosed, only what is known or at least known to exist is suspected, but musculoskeletal tumors are infrequent and therefore very difficult to diagnose or treat. Probably due to their infrequency, the complexity of the radiological images, histopathological appearance, as well as the serious consequences due to inadequate biopsies and treatments, musculoskeletal tumor pathology requires clinical management that must be carried out by a group of specialists with specific training, allowing an adequate diagnosis, introduction of adjuvant therapies, as well as surgical treatment, making multidisciplinary treatment essential today. Imaging studies provide essential information on the nature of each lesion, its size, its anatomical location, the effect on the surrounding bone or soft tissues and the involvement of adjacent joints and neurovascular structures. In this article the authors will discuss the advances in nuclear medicine techniques (scintigraphy, SPECT/CT and PET/CT) and their usefulness in the staging of pediatric malignant musculoskeletal tumors, as well as in the assessment of response, follow-up, and diagnosis of recurrence.


Asunto(s)
Neoplasias , Medicina Nuclear , Niño , Humanos , Tomografía Computarizada por Tomografía de Emisión de Positrones , Cintigrafía , Tomografía Computarizada por Tomografía Computarizada de Emisión de Fotón Único
3.
Artículo en Inglés | MEDLINE | ID: mdl-35241393

RESUMEN

BACKGROUND AND OBJECTIVE: Over the last 15 years, breast cancer (BC) treatment has undergone numerous changes, which have also affected the indications for Sentinel Lymph Node Biopsy (SLNB) as well as the procedures depending on its outcome. The aim of this study is to compare the results of the SLNB carried out at our Center during 2012, when we stopped performing an axillary lymph node dissection (ALND) after the finding of a micrometastasis, with those conducted in 2018, when we started applying Z011 criteria. MATERIALS AND METHODS: We have performed a comparative retrospective observational study, including cN0 BC patients that underwent a SLNB in 2012 versus those that underwent this procedure in 2018. RESULTS: 174 patients from 2012 and 165 from 2018 were studied. We found significant differences between the two groups: in 2018 there were fewer lobular invasive cancers (14 vs 28) (P < .05), a smaller mean pathological size (P < .001), a higher proportion of HER2 and triple negative tumors (28 vs 49) (P < .01) and, finally, an increase in use of neoadjuvant treatments (42.0% vs 6.7%). Regarding axillary involvement, we observed a decrease in both the presence of a positive sentinel node (24.1% in 2018 vs 42.4% in 2012) (P < .0001) as well as in the proportion of ALND performed (12.6% in 2018 vs 21.2% in 2012) and the presence of positive non sentinel nodes after a ALND (59.1% vs74.3%) (ns) CONCLUSION: Although the 2018 cohort that underwent SLNB had more aggressive tumors, there were fewer positive SN and ALND performed. This is probably due to a more accurate radiological diagnosis with ultrasound, that enables to detect cN1 cases before surgery, and to the increasing use of neoadjuvant treatments that may downstage the axilla.


Asunto(s)
Neoplasias de la Mama , Ganglio Linfático Centinela , Humanos , Femenino , Biopsia del Ganglio Linfático Centinela/métodos , Neoplasias de la Mama/diagnóstico por imagen , Neoplasias de la Mama/cirugía , Neoplasias de la Mama/patología , Axila/patología , Escisión del Ganglio Linfático/métodos , Ganglio Linfático Centinela/patología
4.
Artículo en Inglés, Español | MEDLINE | ID: mdl-33824088

RESUMEN

Non-tumour musculoskeletal pathology in children represents a high percentage of the nuclear medicine studies requested by paediatricians. As these are immature bones and joints, in constant growth and remodelling, they present their own physiological and anatomical peculiarities that require a specific management for the paediatric age group. Using different clinical scenarios frequently observed in medical appointments (limping, back pain or fever, among others), we have summarised the possible findings or artefacts that can be obtained in the different Nuclear Medicine explorations, including bone scintigraphy and hybrid images such as PET/CT. To obtain high quality images requires careful attention to technique and positioning in children. Bone scintigraphy is a common paediatric nuclear medicine procedure and plays an important role in the diagnosis of musculoskeletal pathologies and can be complemented by techniques such as SPECT to improve localisation and diagnostic accuracy. In addition, 18F-FDG PET/CT is increasingly applied in the evaluation of children. This article reviews the usual indications of, mainly, bone scintigraphy and 18F-FDG PET/CT in paediatric non-tumour musculoskeletal diseases, how to interpret them properly, being essential to know the normal physiological distribution of each radiopharmaceutical, as well as the common variants of paediatric growth that can simulate disease, implying possible misinterpretations between normal and pathological structures.

5.
Artículo en Inglés, Español | MEDLINE | ID: mdl-33041242

RESUMEN

Clinical problems in the human spine are still common in our society, often causing pain and can also limit movement. Back pain is a very common clinical entity, although difficult to diagnose due to its multifactorial nature. There are multiple processes that can alter the structure of the spine, injure vertebrae and/or the surrounding tissue. For the study of the spine, image diagnosis is essential, and within this, molecular hybrid techniques play an important role by providing us with an image of functional and morphological fusion. Among these, SPECT/CT is key in the diagnosis of traumatic and stress pathology, allowing us to locate hidden vertebral fractures, and is also very useful in degenerative and post-surgical pathology. On the other hand, PET/CT with 18F-FDG also plays an important role in the management and monitoring of infectious and oncological processes. This review describes the application of these hybrid techniques in the different pathologies of the spine and the findings of their images, being very useful for the diagnostic assessment and therapeutic management of the patient.

6.
Infection ; 45(5): 691-696, 2017 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-28243995

RESUMEN

PURPOSE: The role of 18F-fluorodeoxyglucose positron emission tomography-computed tomography (18F-FDG PET/CT) in the diagnosis of metastatic infectious foci in children with catheter-related blood stream infection has been hardly studied, although some authors have reported it benefit in the screening of metastatic foci in adult population. Septic pulmonary emboli are among the most difficult to identify, because many cases do not present pulmonary complaints or abnormal chest radiography. However, diagnosis of these foci has important therapeutic consequences. The purpose of this article is to describe the role of 18F-FDG PET/CT in the diagnosis of septic pulmonary embolism in children with S. aureus catheter-related bacteremia. METHODS: We report 3 children with S. aureus catheter-related bacteremia and normal chest X-ray at admission, in whom 18F-FDG PET/CT led to the diagnosis of unsuspected septic pulmonary emboli, with an impact on clinical management. RESULTS: All patients had hemophilia and implantable venous access ports and presented with fever and normal lung auscultation. Only 1 reported non-specific symptoms (undifferentiated left chest pain). All patients had normal chest X-ray on admission. Catheters were removed within 48 h after admission in 2 cases, and 5 days after admission in the last case, subsiding fever. In 2 children, paired blood cultures were not able to identify bacteremia. However, in all cases catheter tip and subcutaneous port cultures yielded S. aureus and PET/CT detected unsuspected pulmonary metastatic emboli. CONCLUSIONS: 18F-FDG PET/CT should be considered as a useful tool to diagnose septic pulmonary embolism in S. aureus catheter-related bacteremia, especially if conventional diagnostic imaging techniques have failed to reveal possible metastatic foci. Further studies are needed to clarify the usefulness of PET/CT performance in children with CRBSI.


Asunto(s)
Bacteriemia/diagnóstico , Infecciones Relacionadas con Catéteres/diagnóstico , Embolia Pulmonar/diagnóstico , Infecciones Estafilocócicas/diagnóstico , Staphylococcus aureus/fisiología , Bacteriemia/microbiología , Infecciones Relacionadas con Catéteres/microbiología , Niño , Preescolar , Fluorodesoxiglucosa F18/química , Humanos , Tomografía Computarizada por Tomografía de Emisión de Positrones/estadística & datos numéricos , Embolia Pulmonar/microbiología , Sepsis/diagnóstico , Sepsis/microbiología , Infecciones Estafilocócicas/microbiología , Staphylococcus aureus/aislamiento & purificación
7.
Rev Neurol ; 41(12): 709-16, 2005.
Artículo en Español | MEDLINE | ID: mdl-16355354

RESUMEN

INTRODUCTION: Recently, we have published the results of a first surgical series of patients with temporal lobe epilepsy (TLE). We describe a posterior series of patients intervened of TLE, we compare the functional results with the previous series and we finally analyze the causes of changes. PATIENTS AND METHODS: We studied the first 22 consecutive patients surgically intervened of TLE with a minimum post-surgery follow-up of 2 years. Patients showing I and II Engel's grade were used as gold standard for evaluation of pre-surgical complementary studies. RESULTS: We have obtained better functional results: 91% patients showing Engel's grade I, 9% showing grade II and neither III nor IV grades were obtained. Pre-surgical studies changed in comparison with the previous report. The most improving change was observed in video-EEG with foramen-ovale electrodes (FOE) (37%), scalp EEG (26.6%), interictal SPECT (11.7%) and MRI (11.7%). Video-EEG with FOE was the study than showed greater concordance with epileptic focus (95.5%), followed by EEG (86.4%). In 35% of cases, MRI was normal or without valid data for correct localization of focus. CONCLUSIONS: Video-EEG with FOE and TLE surgery are safety methods, which results improve with the experience. Normal or not informative MRI do not should a priori reject those patients with drug-resistant TLE from surgery.


Asunto(s)
Epilepsia del Lóbulo Temporal/cirugía , Procedimientos Neuroquirúrgicos , Adolescente , Adulto , Electrodos , Electroencefalografía/métodos , Epilepsia del Lóbulo Temporal/clasificación , Epilepsia del Lóbulo Temporal/fisiopatología , Femenino , Humanos , Imagen por Resonancia Magnética , Masculino , Persona de Mediana Edad , Cuidados Preoperatorios , Resultado del Tratamiento
8.
Rev Neurol ; 41(1): 4-16, 2005.
Artículo en Español | MEDLINE | ID: mdl-15999323

RESUMEN

AIM: To report our experience in the surgical treatment of temporal-lobe epilepsy. PATIENTS AND METHODS: An analysis was performed of the outcomes of 137 patients submitted to surgery between 1990 and 2001, with a follow-up of more than two years. A study was conducted of the percentages of successful detection by the different complementary tests--MRI, EEG, interictal SPECT, video-EEG with foramen ovale electrodes (FOE), neuropsychological study (NPS)--and the precision with which they reported the epileptogenic focus. RESULTS AND CONCLUSIONS: Successful surgical outcomes (Engel grades I-II): 73.4%. No surgical mortality occurred, although some mild, reversible morbidity was observed. Surgical outcomes were not affected by sex, age, age of onset and the length of time the patient had had the disease, or the frequency of the seizures. No association was found between seizures in the immediate post-operative period and a poorer long term control of the epilepsy. MR images were normal in 25% of patients; in these cases the surgical outcomes (Engel grades I-II at two years: 62%) were significantly poorer than in cases of tumours/cavernomas (86%); RMI studies of other types of lesions gave intermediate results (72%). With respect to the capacity of the different tests to lateralise/locate the epileptogenic focus, video-EEG-FOE proved to be the best, followed by MRI, SPECT, EEG and NPS.


Asunto(s)
Mapeo Encefálico/métodos , Electrodos , Electroencefalografía/métodos , Epilepsia del Lóbulo Temporal/cirugía , Adolescente , Adulto , Anciano , Niño , Preescolar , Epilepsia del Lóbulo Temporal/patología , Epilepsia del Lóbulo Temporal/fisiopatología , Femenino , Estudios de Seguimiento , Humanos , Lactante , Imagen por Resonancia Magnética , Masculino , Persona de Mediana Edad , Periodo Posoperatorio , Estudios Retrospectivos , Resultado del Tratamiento
9.
Rev Clin Esp ; 205(7): 316-21, 2005 Jul.
Artículo en Español | MEDLINE | ID: mdl-16029757

RESUMEN

OBJECTIVES: To assess the usefulness of adrenal scintigraphy for clinical evaluation of adrenal incidentalomas, and its relation with pathological diagnosis and follow-up. PATIENTS AND METHODS: We have studied 46 patients with unilateral adrenal incidentaloma of size between 10 and 100 mm (average 30.5 +/- 19 mm). The lesions were discovered with abdominal computerized tomography in the study of a primary tumor (22%) or in the evaluation of benign pathology (78%). Adrenal scintigraphy assessed uptake in adrenal incidentaloma. Hormonal study included urinary catecholamines, plasma cortisol after dexamethasone, adrenal androgens, and renin and aldosterone in hypertensive patients. Five patients were operated, FNAB was carried out in three patients, and in the rest average follow-up was 29 +/- 21 months. Adrenal incidentaloma was considered nonfunctional if the lesion did not modified its size nor showed analytical alterations along a follow-up higher than 8 months. RESULTS: Of 46 adrenal lesions, seven didn't show uptake (three metastases, one cyst, one adrenal carcinoma, one pheochromocytoma, and one angiomyolipoma), 34 showed excessive uptake (29 nonfunctional adrenal nodules and 5 hyperfunctional adrenal nodules), and five had normal uptake (nonfunctional adrenal nodules). Adrenal scintigraphy was compatible in all cases with cytological study or the response to chemotherapy. Along the follow-up, growth of the lesion was demonstrated in 23%, and reduction or disappearance of the lesion in 11%, with no hormonal significant changes. CONCLUSIONS: Detection of a lesion with no uptake in adrenal scintigraphy forces to carry out complementary explorations in order to rule out malignant pathology. A lesion with excessive uptake is indicative of a benign process and should be assessed with hormonal determinations.


Asunto(s)
Neoplasias de las Glándulas Suprarrenales/diagnóstico por imagen , Neoplasias de las Glándulas Suprarrenales/sangre , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Hidrocortisona/sangre , Hallazgos Incidentales , Masculino , Persona de Mediana Edad , Cintigrafía
10.
Rev Neurol ; 32(1): 6-10, 2001.
Artículo en Español | MEDLINE | ID: mdl-11293102

RESUMEN

OBJECTIVE: To localize the cortical regions for language in patients who are to have brain surgery. PATIENTS AND METHODS: We made a SPECT (Single Photon Emission using Computerized Tomography) study of cerebral perfusion in 14 patients with drug-resistant temporal epilepsy who were candidates for brain surgery. The patients were selected consecutively from those attending for surgical assessment. We selected the patients in whom two 99mTc-HMPAO studies could be done in the same week: one without sensory stimulation and one whilst listening and repeating a series of ordinary words in fairly frequent use. The two studies were assessed qualitatively (on a 16 colour image scale, with a background subtraction of 20% and standardized to the point of maximum uptake). Changes were considered to be significant when a greater intensity of two colours was localized and semiquantitative (with regular areas of interest, of 4 x 4 pixels, placed on the region in which the qualitative change was observed and referenced to cerebellar activity). RESULTS: We found increased perfusion in the temporo-parietal regions in 11 of the 14 patients. In most (9/14 cases) this was bilateral and in two cases on the left only. We observed a certain predominant pattern: a bilateral increase in temporal perfusion, involving the more anterior regions of the left hemisphere and also the middle and posterior regions of the right hemisphere. The maximum percentage increase in perfusion on semiquantitative assessment was 12%. CONCLUSION: Although the changes seen may correspond to activation in the cortical regions related to different cerebral functions, we consider that with the SPECT technique one may detect changes in perfusion of the regions of the brain which are involved in language processing.


Asunto(s)
Mapeo Encefálico , Circulación Cerebrovascular , Epilepsia del Lóbulo Temporal/psicología , Lóbulo Parietal/diagnóstico por imagen , Habla/fisiología , Lóbulo Temporal/diagnóstico por imagen , Tomografía Computarizada de Emisión de Fotón Único , Adolescente , Adulto , Dominancia Cerebral , Resistencia a Medicamentos , Epilepsia del Lóbulo Temporal/diagnóstico por imagen , Epilepsia del Lóbulo Temporal/cirugía , Femenino , Humanos , Procesamiento de Imagen Asistido por Computador , Masculino , Persona de Mediana Edad , Lóbulo Parietal/irrigación sanguínea , Lóbulo Parietal/fisiopatología , Cuidados Preoperatorios , Radiofármacos , Exametazima de Tecnecio Tc 99m , Lóbulo Temporal/irrigación sanguínea , Lóbulo Temporal/fisiopatología
11.
An Med Interna ; 17(4): 201-3, 2000 Apr.
Artículo en Español | MEDLINE | ID: mdl-10893773

RESUMEN

We present the case of a 23 year old female with two incidentally detected hepatic mass that have not clinically o radiologically specific findings. Nuclear medicine tracers, including colloids and hepatobiliary agents showing the characteristic findings of focal nodular hyperplasia: Hypervascularization, normal uptake of colloids, accumulation of hepatobiliary tracer and hot spots due to the retention of this tracer during the clearance fhase. The patient was underwent hepatectomy. The examination of surgical specimen revealed focal nodular hyperplasia. The scintigraphic studies could be an useful tool in the noninvasive diagnosis of liver masses.


Asunto(s)
Hiperplasia Nodular Focal/diagnóstico por imagen , Adulto , Diagnóstico Diferencial , Femenino , Humanos , Neoplasias Hepáticas/diagnóstico por imagen , Cintigrafía
13.
Nucl Med Commun ; 17(1): 29-32, 1996 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-8692469

RESUMEN

Adrenal scintigraphy has been shown to be a useful procedure for the characterization of incidentally discovered adrenal tumours. The functional evaluation of these patients is controversial. This paper describes the biochemical and pathological findings in five patients with asymptomatic adrenal masses and unilateral concordant adrenocortical scintigraphic uptake. All the patients were diagnosed as having subclinical Cushing's Syndrome, without clinical or biochemical adrenocortical dysfunction. Scintigraphy is the most sensitive method for detecting an adrenal adenoma in the subclinical setting when the disease is not yet demonstrable by biochemical methods.


Asunto(s)
Corteza Suprarrenal/diagnóstico por imagen , Neoplasias de las Glándulas Suprarrenales/diagnóstico por imagen , Síndrome de Cushing/diagnóstico por imagen , Corteza Suprarrenal/patología , Neoplasias de las Glándulas Suprarrenales/diagnóstico , Neoplasias de las Glándulas Suprarrenales/patología , Anciano , Síndrome de Cushing/diagnóstico , Síndrome de Cushing/etiología , Femenino , Humanos , Imagen por Resonancia Magnética , Persona de Mediana Edad , Neoplasias Ováricas/diagnóstico por imagen , Neoplasias Ováricas/patología , Cintigrafía , Tomografía Computarizada por Rayos X
15.
Clin Radiol ; 49(11): 796-9, 1994 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-7955847

RESUMEN

To evaluate the diagnostic contribution of adrenal scintigraphy with 75-Se-selenomethylcholesterol in adrenal masses, 42 patients have been studied. All of them had a solid adrenal mass discovered on computed tomography (seven bilateral). None of the patients showed any symptoms or clinical signs that might indicate the existence of adrenal dysfunction. Twenty-nine of them had known extra-adrenal primary malignant disease. Forty-nine adrenal tumours were detected with an average size of 3.29 cm (range 1.5-12 cm). Eighteen lesions showed increased uptake of radiocholesterol on the side of the adrenal mass, all of which were either proven to be benign, or behaved in a benign fashion. Twelve lesions showed normal uptake (10 in the benign group and one lung carcinoma metastasis), all but one (2.5 cm) being smaller than 2 cm. Decreased uptake was observed in 20 lesions (15 metastases, two nonfunctional adrenal carcinomas, one myelolipoma and two tuberculous infectious lesions). Adrenocortical scintigraphy provides functional information about adrenal masses and is useful in differentiating between benign and malignant lesions.


Asunto(s)
Neoplasias de las Glándulas Suprarrenales/diagnóstico por imagen , Glándulas Suprarrenales/diagnóstico por imagen , Colesterol/análogos & derivados , Neoplasias de las Glándulas Suprarrenales/patología , Glándulas Suprarrenales/patología , Adulto , Anciano , Diagnóstico Diferencial , Femenino , Humanos , Masculino , Persona de Mediana Edad , Cintigrafía , Tomografía Computarizada por Rayos X
16.
Int J Biol Markers ; 8(4): 203-7, 1993.
Artículo en Inglés | MEDLINE | ID: mdl-8138659

RESUMEN

Serum MCA levels were determined in 173 consecutive patients with breast cancer in order to assess the clinical utility of MCA for the detection of bone metastases. Bone pathology was diagnosed by scintigraphy, radiology and clinical follow-up. Metastases were found in 37 patients, benign lesions in 25, and in 111 no bone lesions were found. Eighteen of the 173 bone scans were considered indeterminate for metastases. Based on the receiver-operating characteristic curves (ROC) analysis, the cut-off level for MCA was set at 20 U/ml. Only in 4 of the 37 patients with bone metastases MCA was below 20 U/ml. All 4 patients had completed their chemotherapy course within six months before MCA determination. Only in 6 patients of the 136 without bone metastases MCA levels were above 20 U/ml. Of the 18 patients with indeterminate bone scans, 15 had benign lesions and all of them had MCA levels below 20 U/ml. MCA determination is a sensitive method for the detection of bone metastases in breast carcinoma. We encourage the use of this procedure for the selection of high-risk groups or as a complementary method for the interpretation of bone scintigraphy.


Asunto(s)
Antígenos de Neoplasias/sangre , Antígenos de Carbohidratos Asociados a Tumores , Biomarcadores de Tumor/sangre , Neoplasias Óseas/diagnóstico , Neoplasias Óseas/secundario , Neoplasias de la Mama/sangre , Adulto , Anciano , Anciano de 80 o más Años , Neoplasias Óseas/sangre , Neoplasias de la Mama/inmunología , Errores Diagnósticos , Femenino , Humanos , Persona de Mediana Edad , Pronóstico , Curva ROC , Sensibilidad y Especificidad , Medronato de Tecnecio Tc 99m
18.
Rev Clin Esp ; 192(9): 428-30, 1993 May.
Artículo en Español | MEDLINE | ID: mdl-8516507

RESUMEN

It is described the case of a patient with Ovarian Cystadenoma in whom a 3.5 cm nodular lesion was accidentally detected in her left suprarenal gland. She had no signs of hypercortisolism or any other suprarenal pathology and was symptomless. Determinations in the urine of 24 hours of Cortisol, Adrenaline and Noradrenaline, 17-ketosteroids and Tetrahydroaldosterone were normal. Daily rhythm and plasmatic determinations of ACTH, cortisol and 11-deoxycortisol were normal. The Dexamethasone suppression test was also normal. In the suprarenal gammagraphy it appeared an intense captation by left suprarenal without visualization of right gland. A left suprarenalectomy was performed and the anatomopathological analysis showed a clear cell corticoadrenal adenoma. Therefore the only data of the function of suprarenal adenoma was the one coming from gammagraphy. We thought that the adenoma was responsible of practically all the corticoadrenal function without reaching pathological levels, meeting the criteria of "pre-Cushing" syndrome or subclinical Cushing, due to the fact that the contralateral gland was not seen in the gammagraphy. Therefore in the characterization of certain tumors which appear clinically and biochemically as non functional, the suprarenal gammagraphy could be a technique of great usefulness for the diagnosis.


Asunto(s)
Adenoma/diagnóstico , Neoplasias de las Glándulas Suprarrenales/diagnóstico , Síndrome de Cushing/diagnóstico , Neoplasias Ováricas/diagnóstico , Adenoma/diagnóstico por imagen , Neoplasias de las Glándulas Suprarrenales/diagnóstico por imagen , Diagnóstico Diferencial , Femenino , Humanos , Persona de Mediana Edad , Neoplasias Ováricas/diagnóstico por imagen , Cintigrafía
19.
An Med Interna ; 9(5): 229-33, 1992 May.
Artículo en Español | MEDLINE | ID: mdl-1324016

RESUMEN

A common cause of the Cushing's Syndrome (CS) is nodular suprarenal hyperplasia (NSH), which is characterized by the presence of nodes in both suprarenal glands. Its pathophysiology is not well known and its diagnosis is quite difficult due to the heterogenicity of the biochemical and radiological data. We analyzed the suprarenal gammagraphies (SRG) of 7 patients with anatomopathological diagnosis of NSH. Bilateral uptake was observed in all cases and in five patients, such bilateral uptake presented a clear asymmetry. We believe that these observations demonstrate a bilateral suprarenal affectation and are of great use in order to orientate the diagnosis of NSH and, especially, in order to differentiate it from other suprarenal diseases causing CS, like adenomas, in which uptake is unilateral.


Asunto(s)
Glándulas Suprarrenales/patología , Síndrome de Cushing/diagnóstico por imagen , Glándulas Suprarrenales/metabolismo , Hormona Adrenocorticotrópica/sangre , Adulto , Colesterol , Síndrome de Cushing/etiología , Síndrome de Cushing/fisiopatología , Femenino , Humanos , Hidrocortisona/metabolismo , Hiperplasia , Masculino , Persona de Mediana Edad , Cintigrafía , Tomografía Computarizada por Rayos X
20.
Rev Clin Esp ; 188(7): 332-8, 1991 Apr.
Artículo en Español | MEDLINE | ID: mdl-1784760

RESUMEN

A retrospective study is presented of 19 patients who suffered Hypercortisolism who were examined by adrenal gammagraphy, echography, and CT scan in order to evaluate the usefulness of gammagraphy in the diagnostic approximation of this pathology. The gammagraphy findings had an excellent correlation with anatomopathologic findings, probably due to the combined morphologic and functional evaluation obtained with this technique which facilitates a complementary vision to the other diagnostic image exams (CT scan and echography) which, although they are the first choice given their availability and good resolution, they can easily lead to diagnostic errors which can be avoided if we can perform an adrenal gammagraphy; it is of special interest in the study of macro-micro-nodular hyperplasia and its differentiation from single adenomas.


Asunto(s)
Corteza Suprarrenal/diagnóstico por imagen , Síndrome de Cushing/diagnóstico por imagen , Adulto , Femenino , Rayos gamma , Humanos , Masculino , Persona de Mediana Edad , Cintigrafía , Estudios Retrospectivos
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