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Dermatol Surg ; 49(1): 66-71, 2023 01 01.
Artículo en Inglés | MEDLINE | ID: mdl-36533799

RESUMEN

BACKGROUND: Melasma is a common acquired disorder of hyperpigmentation which is difficult to treat. OBJECTIVE: We aim to evaluate the efficacy and safety of combined microneedling with trichloroacetic acid in the treatment of melasma. PATIENTS AND METHODS: Forty women with facial melasma were included and randomly classified into 2 groups. Group A included 20 patients treated with bimonthly session of trichloroacetic acid 25% peeling (8 sessions) combined with a monthly session of microneedling (4 sessions). Group B included the other 20 patients that were treated by bimonthly trichloroacetic acid 25% peeling session (8 sessions) alone. RESULTS: After 1 and 3 months of treatment, the mean melasma area and severity index, modified melasma area and severity index, and melasma severity index scores showed significant improvement in each group (p < .05 for each). At 1 and 3 months, the mean percentages of change of all scores were significantly higher in group A than group B (p < .05). CONCLUSION: Combined trichloroacetic acid peel with microneedling is effective and a safe option for treating melasma.


Asunto(s)
Quimioexfoliación , Hiperpigmentación , Melanosis , Femenino , Humanos , Quimioexfoliación/efectos adversos , Cara , Hiperpigmentación/etiología , Melanosis/terapia , Melanosis/etiología , Resultado del Tratamiento , Ácido Tricloroacético/efectos adversos
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