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J Fr Ophtalmol ; 37(10): 780-6, 2014 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-25278483

RESUMEN

PURPOSE: Extensive macular atrophy with pseudodrusen-like appearance (EMAP) is a recently described entity. We describe the first observations of choroidal neovascularization (CNV) associated with EMAP in 3 patients. METHODS: Nineteen consecutive patients with EMAP were retrospectively investigated for the presence of CNV and treatment outcomes. Each patient underwent a complete ophthalmologic examination including color fundus photograpy, fluorescein angiography (FA), indocyanine green angiography (ICG) and spectral-domain optical coherence tomography (SD-OCT). RESULTS: Retrospective analysis revealed choroidal neovascularization in 3 patients (4 eyes) out of 19 patients with EMAP. In these patients, laser photocoagulation or intravitreal injections of ranibizumab led to resolution of retinal exudation with limited functional improvement. CONCLUSION: CNV is a possible complication of EMAP, a recently reported form of macular atrophy resembling geographic atrophy. Laser photocoagulation and anti-VEGF treatment appear to be two valuable therapeutic options.


Asunto(s)
Neovascularización Coroidal/complicaciones , Atrofia Geográfica/complicaciones , Drusas Retinianas/complicaciones , Inhibidores de la Angiogénesis/administración & dosificación , Anticuerpos Monoclonales Humanizados/administración & dosificación , Neovascularización Coroidal/diagnóstico , Neovascularización Coroidal/terapia , Femenino , Atrofia Geográfica/diagnóstico , Atrofia Geográfica/terapia , Humanos , Inyecciones Intravítreas , Coagulación con Láser , Masculino , Persona de Mediana Edad , Ranibizumab , Drusas Retinianas/diagnóstico , Drusas Retinianas/terapia , Estudios Retrospectivos , Factor A de Crecimiento Endotelial Vascular/antagonistas & inhibidores
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