Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 43
Filtrar
1.
Scand J Surg ; 99(4): 250-5, 2010.
Artículo en Inglés | MEDLINE | ID: mdl-21159598

RESUMEN

AIMS: The purpose of this study was to compare retrospectively the mid-term clinical and radiological results of three contemporary knee designs in cohorts operated on in the same hospital during the same time period. MATERIALS AND METHODS: We evaluated mid-term clinical and radiographic outcome of three contemporary total knee designs (the AGC V2, the Duracon and the Nexgen) in 104 consecutive patients (129 knees) operate on for primary knee osteoarthritis at our hospital. The mean indexed age at the time of the operation was 69.2 years (range, 49.3 to 81.1 years). The mean follow-up time was 6.0 years (range, 0.2 to 7.9). All patients were followed for at least three years or until the first revision. In the survival analyses, the end point was defined as, revision for any reason. RESULTS: The Kaplan-Meier survival analysis showed a 98% (95% CI 94-100) survival rate for the NexGen, a 98% (95% CI 93-100) for the AGC and a 90% (95% CI 81-99) for the Duracon design at six years. Both the mean KSS for pain, KSS for function and the mean clinical knee score improved significantly in all three groups. There was no difference between the three designs in mid-term survivorship. CONCLUSIONS: Most of the revisions could be directly linked to perioperative surgical errors. In conclusion, the most recently introduced knee replacements of the present study (Duracon and Nexgen) did not show any clinically significant benefit over the older design (AGC) in the mid-term.


Asunto(s)
Artroplastia de Reemplazo de Rodilla , Prótesis de la Rodilla , Osteoartritis de la Rodilla/cirugía , Anciano , Anciano de 80 o más Años , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Osteoartritis de la Rodilla/complicaciones , Osteoartritis de la Rodilla/fisiopatología , Diseño de Prótesis , Falla de Prótesis , Recuperación de la Función , Reoperación , Factores de Tiempo , Resultado del Tratamiento , Soporte de Peso
2.
Osteoarthritis Cartilage ; 17(9): 1144-50, 2009 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-19374960

RESUMEN

OBJECTIVE: To evaluate the effect of waiting time on health and quality of life outcomes and costs of medication in total hip replacement (THR) patients in a randomized clinical trial. METHODS: 395 THR patients were recruited into the study. When placed on the waiting list, patients were randomized into a short (< or =3 months) or a non-fixed waiting time (NFWT) (>3 months) group. In the final analyses 309 patients (179 women) with a mean age of 65 years were included. Health-related quality of life (HRQoL) (generic 15D), and pain and function (modified Harris Hip Score (HHS)) were calculated when placed on the waiting list, at hospital admission, and at 3 and 12 months postoperatively. The costs of disease-specific medication were calculated at the same measurement points. All analyses were performed using the intention-to-treat (ITT) principal. RESULTS: Of the recruited patients, 309 (78%) completed the follow-up (short group 140 and non-fixed group 169 patients). The mean waiting time was 74 days in the short and 194 days in the NFWT groups. In the ITT analyses there were no statistically significant differences between the groups in the weekly use and costs of medication, HRQoL or HHS at baseline, at admission, or 3 or 12 months after surgery. The only difference was in total medication costs during the waiting time period, at EUR 83 and 171, respectively. CONCLUSIONS: The length of the waiting time did not generate different effects on the studied health and quality of life outcomes of the randomized groups. However, those in short waiting time group reached earlier better HRQoL.


Asunto(s)
Artroplastia de Reemplazo de Cadera/economía , Osteoartritis de la Cadera/cirugía , Evaluación de Resultado en la Atención de Salud/economía , Anciano , Artroplastia de Reemplazo de Cadera/estadística & datos numéricos , Femenino , Finlandia , Humanos , Masculino , Persona de Mediana Edad , Osteoartritis de la Cadera/economía , Evaluación de Resultado en la Atención de Salud/estadística & datos numéricos , Satisfacción del Paciente/economía , Satisfacción del Paciente/estadística & datos numéricos , Calidad de Vida/psicología , Factores de Tiempo , Listas de Espera
3.
J Bone Joint Surg Br ; 90(12): 1562-9, 2008 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-19043125

RESUMEN

We have analysed from the Finnish Arthroplasty Register the long-term survivorship of the 12 most commonly-used cemented implants between 1980 and 2005 in patients aged 55 years or older with osteoarthritis. Only two designs of femoral component, the Exeter Universal and the Müller Straight femoral component had a survivorship of over 95% at ten years with revision for aseptic loosening as the endpoint. At 15 years of the femoral and acetabular component combinations, only the Exeter Universal/Exeter All-poly implant had a survival rate of over 90% with revision for aseptic loosening as the endpoint. In the subgroup of patients aged between 55 and 64 years, survivorship overall was less than 90% at ten years. The variation in the long-term rates of survival of different cemented hip implants was considerable in patients aged 55 years or older. In those aged between 55 and 64 years, none of the cemented prostheses studied yielded excellent long-term survival rates (> or = 90% at 15 years).


Asunto(s)
Artroplastia de Reemplazo de Cadera/métodos , Cementos para Huesos/uso terapéutico , Prótesis de Cadera , Osteoartritis de la Cadera/cirugía , Falla de Prótesis , Anciano , Artroplastia de Reemplazo de Cadera/estadística & datos numéricos , Análisis de Falla de Equipo/estadística & datos numéricos , Femenino , Finlandia , Estudios de Seguimiento , Prótesis de Cadera/normas , Prótesis de Cadera/estadística & datos numéricos , Humanos , Masculino , Persona de Mediana Edad , Diseño de Prótesis , Reoperación/estadística & datos numéricos , Factores de Tiempo , Resultado del Tratamiento
4.
Hip Int ; 18(2): 108-11, 2008.
Artículo en Inglés | MEDLINE | ID: mdl-18645984

RESUMEN

The aim of the study was to validate a Finnish version of the internationally used Western Ontario and McMasters University osteoarthritis index (WOMAC) questionnaire, by testing its reliability, validity and responsiveness. The subjects of the study were patients scheduled for elective total knee arthroplasty (TKA) or total hip arthroplasty (THA). The patients completed the WOMAC questionnaire twice prior to surgery and once postoperatively to enable reliability, construct validity and responsiveness analysis. Test-retest reliability could be calculated for 67 patients (37 TKA and 30 THA). The intraclass correlation coefficients (ICC a) exceeded 0.9 with the exception of the stiffness subscale which averaged 0.8. Correlation of the preoperative WOMAC total score with the Harris Hip Score (HHS) in 30 patients and American Knee Society Score (AKSS) in 37 patients were mediocre ranging from 0.48 to 0.53. To test responsiveness, the first preoperative and the postoperative WOMAC scores of 74 subjects were compared (41 TKA and 33 THA). Standard response means (SRM) and effect sizes (ES) exceeded the recommended score of 0.8, ranging from 1.15 to 2.35. In conclusion the Finnish translation of the WOMAC questionnaire performs as the original, is valid and can be used in future studies of osteoarthritis.


Asunto(s)
Osteoartritis de la Cadera/diagnóstico , Osteoartritis de la Rodilla/diagnóstico , Índice de Severidad de la Enfermedad , Comparación Transcultural , Finlandia , Indicadores de Salud , Articulación de la Rodilla/fisiopatología , Osteoartritis de la Cadera/fisiopatología , Osteoartritis de la Rodilla/fisiopatología , Rango del Movimiento Articular , Reproducibilidad de los Resultados , Encuestas y Cuestionarios
5.
Proc Inst Mech Eng H ; 220(2): 399-407, 2006 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-16669405

RESUMEN

All patients with total hip arthroplasty (THA) are exposed to soluble or particulate forms of Co and Cr. Adverse effects of these wear products are not known. Data from Nordic registries is used to estimate adverse effects on a large scale, based mostly on metal-on-polyethylene bearings. Cancer incidence was in line with the general population when the patients were operated on for all indications and significantly decreased when the indication was primary osteoarthritis. Stomach cancer and colorectal cancers were significantly reduced and prostate cancer and skin melanoma significantly increased. There was no significant excess of cancer in target organs, i.e. liver, kidney, or haematopoietic cancers. THA patients had reduced mortality and extended life expectancy compared with standard Nordic populations. All-site cancer incidence of the first-generation metal-on-metal McKee-Farrar patients operated on for primary osteoarthritis was in line with the general population after follow-up for up to 28 years. General mortality of these patients was also reduced and they also had an extended life expectancy. Temporary increases in haematopoietic cancers at different follow-up periods were seen in some cohorts. This malignancy deserves a special record linkage monitoring while large numbers of young patients are provided with the second generation of metal-on-metal prostheses.


Asunto(s)
Artroplastia de Reemplazo de Cadera/mortalidad , Prótesis de Cadera/clasificación , Prótesis de Cadera/estadística & datos numéricos , Metales , Neoplasias/mortalidad , Sistema de Registros , Medición de Riesgo/métodos , Materiales Biocompatibles , Causas de Muerte , Estudios de Cohortes , Dinamarca/epidemiología , Finlandia/epidemiología , Humanos , Incidencia , Noruega/epidemiología , Factores de Riesgo , Suecia/epidemiología
6.
Br J Surg ; 93(1): 33-9, 2006 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-16329082

RESUMEN

BACKGROUND: In this randomized prospective study the short- and long-term outcomes of patients undergoing inguinal hernia repair with either Lichtenstein mesh or the Prolene Hernia System (PHS) were evaluated. METHODS: Postoperative pain and time to return to work, driving and sporting hobbies were recorded after 300 inguinal hernia repairs done by one of the two methods. Long-term sequelae and complications were assessed at follow-up visits 1 week, 1 month and 1 year after the operation. RESULTS: The median duration of operation for unilateral primary hernia was 37 min for the Lichtenstein operation and 27 min for the PHS procedure (P < 0.001). Postoperative pain was similar after both operations. Median sick leave was 7 days in both groups. Time to driving a car was 4 versus 3 days, and time to return to sporting hobbies 13 versus 11 days, in the Lichtenstein and PHS groups, respectively. Apart from a residual femoral hernia after Lichtenstein repair, no recurrent inguinal hernias were detected. CONCLUSION: Both Lichtenstein and PHS methods resulted in rapid recovery and low recurrence rates. The PHS operation was significantly quicker.


Asunto(s)
Hernia Inguinal/cirugía , Mallas Quirúrgicas , Adulto , Anciano , Método Doble Ciego , Femenino , Hernia Inguinal/rehabilitación , Humanos , Tiempo de Internación , Masculino , Persona de Mediana Edad , Dolor Postoperatorio/etiología , Estudios Prospectivos , Recurrencia , Resultado del Tratamiento
7.
Acta Orthop Scand ; 72(5): 433-41, 2001 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-11728068

RESUMEN

The Finnish Arthroplasty Register was established in 1980. Between 1980 and 1999, 62,841 primary and 12,224 revision total hip arthroplasties (THA) were recorded. The annual number of both primary and revision THA has increased: in 1999, the incidence of primary THAs was 93/100,000. 174 implant designs have been used, but the 6 commonest implants comprised 82% in 1999. Since the late 1980s, more than 40% of the hips were inserted without cement. Over 47% of the cementless primary hip prostheses were used in patients younger than 60 years and over 93% of the cemented primary hips were used in patients 60 years or older. The 10-year survival rate was 72 (95% CI 67-76)% in patients younger than 55 years and 90 (89-91)% in patients older than 70 years. The commonest reasons for revision were aseptic loosening (65%), dislocation (9%) and infection (7%). In revisions, the 5-year survival of the cementless hip prosthesis improved over time: it was 85 (82-87)% in 1985-1989, 89 (88-91)% in 1990-1994 and 92 (88-95)% in 1995-1999. There are striking differences between the Arthroplasty Registers of Scandinavia as regards the end-point definition of survival. The Finnish Arthroplasty Register considers all reasons for revisions as the end-point of survival, but the Swedish register takes into account only aseptic loosening, so direct comparisons between registers are not possible. Recent data from the Finnish Arthroplasty Register indicate that the results of total hip replacements are improving in Finland. With the civic registration number, one can link and match data files. For example, with use of the Finnish Cancer Register, we found no increase in the risk of cancer after a THA.


Asunto(s)
Artroplastia de Reemplazo de Cadera/estadística & datos numéricos , Sistema de Registros , Finlandia , Humanos , Falla de Prótesis , Reoperación
8.
JAMA ; 285(19): 2474-80, 2001 May 16.
Artículo en Inglés | MEDLINE | ID: mdl-11368700

RESUMEN

CONTEXT: Hallux valgus is a common foot deformation in adults, but evidence for effectiveness of surgical and conservative treatments for this condition is limited. OBJECTIVE: To compare the effectiveness of surgical and orthotic treatment with no treatment in patients with hallux valgus. DESIGN AND SETTING: Randomized controlled trial conducted in 4 general community hospitals in Finland in 1997-1998, with a follow-up period of 12 months. PARTICIPANTS: Two hundred nine consecutive patients (mean age, 48 years; 93% women) with a painful bunion and a hallux valgus angle 35 degrees or less. INTERVENTIONS: Patients were randomly assigned to surgery (distal chevron osteotomy; n = 71), orthosis (n = 69), or a 1-year waiting list (control group, n = 69). MAIN OUTCOME MEASURES: Pain intensity during walking on a visual analog scale (0-100), patient assessment of global improvement, number of painful days, cosmetic disturbance, footwear problems, functional status, and treatment satisfaction, compared among treatment groups. RESULTS: Follow-up rates at 6 and 12 months were 99% and 98%, respectively. At 6 months, pain intensity decreased more in the surgical group than in the control group (adjusted mean differences, -20 [95% confidence interval (CI), -28 to -12]) and more in orthosis than in the control groups (adjusted mean difference, -14 [95% CI, -22 to -6. At 1 year, pain intensity decreased more in the surgical than in the control groups (adjusted mean difference, -19 [95% CI, -28 to -10]) and more than in the surgical and orthosis groups (adjusted mean difference, -14 [95% CI, -22 to -5]). At 1 year, 83%, 46%, and 24% in the surgery, orthosis, and control groups, respectively, thought they had improved compared with baseline (number needed to treat), 1.7 between surgical and control groups). Number of painful days, cosmetic disturbance, and footwear problems were least and functional status and satisfaction with treatment were best in the surgical group. CONCLUSIONS: Surgical osteotomy is an effective treatment for painful hallux valgus. Orthoses provide short-term symptomatic relief.


Asunto(s)
Hallux Valgus/terapia , Femenino , Hallux Valgus/diagnóstico por imagen , Hallux Valgus/economía , Hallux Valgus/cirugía , Humanos , Masculino , Persona de Mediana Edad , Aparatos Ortopédicos/economía , Osteotomía/economía , Dolor , Satisfacción del Paciente , Radiografía , Resultado del Tratamiento
9.
Bone ; 27(4): 551-7, 2000 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-11033451

RESUMEN

Experimental osteolathyrism, induced by dietary aminoacetonitrile (AAN), was used to study the effect of altered extracellular matrix on the expression of connective tissue components in long bone healing. AAN inhibits lysyl oxidase, which is needed for the formation of collagen cross-link precursors, and is also shown to act as a regulator of Ras. Fractured tibias in lathyritic rats develop excessive amounts of mechanically weak callus tissue with irregular cartilage and reduced glycosaminoglycan accumulation. Cartilage-specific proteins (collagen types II, IX, and X and aggrecan) were expressed temporally much wider in lathyritic calluses than in the controls, and active transcription was observed even during the fibrous and ossifying stages. Soft connective tissue was still present in 2- and 3-week-old lathyritic calluses and could explain the elevated type III collagen, biglycan, and decorin mRNA levels. Both transforming growth factor (TGF)-beta1 and c-Ha-ras, which control cell growth and differentiation, were upregulated during the cartilaginous stage. The maximal expression of TGF-beta1 preceded that of ras in osteolathyrism.


Asunto(s)
Proteínas de la Matriz Extracelular/genética , Curación de Fractura , Genes ras , Latirismo/genética , Tibia/metabolismo , Factor de Crecimiento Transformador beta/genética , Animales , Masculino , Proteínas Quinasas Activadas por Mitógenos/genética , Ratas , Ratas Wistar
10.
J Arthroplasty ; 14(3): 272-80, 1999 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-10220179

RESUMEN

Nationwide, computer-based reporting of all arthroplasties performed in Finland was started in January 1980. Using data from these records, a cohort of 31,651 polyethylene-on-metal total hip arthroplasty (THA) patients was followed up for cancer, using Finnish Cancer Registry data, from 1980 to 1995. During follow-up, 2,367 cancers were observed. There were statistically significantly fewer cancers among the THA patients (standardized incidence ratio [SIR], 0.90; 95% confidence interval [CI], 0.87-0.93). SIRs for cancers of the lung (0.69) and stomach (0.77) were significantly below unity. There was no significantly increased risk at any site. The SIR for cancer overall in male THA patients was below unity during the first 3 years after THA but returned to unity thereafter. The low SIR among men during the first 3 years was largely because the lung cancer SIR was 0.47 (95% CI, 0.35-0.62). In women, the SIR remained around 0.93 throughout follow-up. The SIR for stomach cancer was below unity only in women (SIR, 0.67; 95% CI, 0.51-0.86). For cancer of the urinary bladder, the SIR during the first 3 years after THA was below unity but later slightly above it (SIR, 1.24 in relation to > or =3 years of follow-up; 95% CI, 0.99-1.52). For myeloma and leukemia, SIRs were greater than unity only for THA patients followed up for 3 to 9 years. The study findings, in contrast to previously reported findings, do not indicate that there is any increased risk of hematopoietic cancers after THA using polyethylene-on-metal prostheses. SIRs relating to soft tissue cancers and bone sarcomas did not differ significantly from unity. No sarcoma was observed at the site of a prosthesis. THA seems to play no major role in cancer causation.


Asunto(s)
Artroplastia de Reemplazo de Cadera/estadística & datos numéricos , Neoplasias/epidemiología , Estudios de Cohortes , Femenino , Finlandia/epidemiología , Estudios de Seguimiento , Prótesis de Cadera/efectos adversos , Prótesis de Cadera/estadística & datos numéricos , Humanos , Incidencia , Masculino , Metales/efectos adversos , Diseño de Prótesis , Sistema de Registros/estadística & datos numéricos , Factores de Riesgo , Factores de Tiempo
11.
Acta Orthop Scand ; 70(6): 609-17, 1999 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-10665728

RESUMEN

A nationwide, computer-based survey of all total joint arthroplasties performed in Finland has been carried out since January 1980. From these records, a cohort of 9,444 patients, with 51,756 person-years, after primary operation with a total polyethylene-on-metal knee arthroplasty (TKA) was followed up for cancer through the Finnish Cancer Register up to December 31, 1996. During the follow-up, 706 cancers were observed. The expected number, based on national rates, was 719; therefore, the standardized incidence ratio (SIR) for all cancers was 0.98. The SIRs for non-Hodgkin's lymphoma (1.40), Hodgkin's disease (1.24) and multiple myeloma (1.54) were increased, but only that of non-Hodgkin's lymphoma was statistically significant 3-10 years after the operation. The numbers of observed cases of prostate cancer exceeded that of expected, with a SIR value of 1.49. A low SIR of lung cancer was observed among men, especially during the first 3 years (0.61), but not in women. The SIR for colon cancer was below unity in women only (SIR 0.70). The SIR for cancer of the urinary organs was close to unity (0.97). SIR relating to soft tissue and bone cancer did not differ significantly from unity, and none of the 6 sarcomas was observed at the site of a prosthesis. The overall cancer risk after TKA done for primary osteoarthrosis seems not to be increased. The increases in lymphoma and prostate cancer risk, however, are observations that could be related to TKA and justify further follow-up of the cohort.


Asunto(s)
Artroplastia de Reemplazo de Rodilla/efectos adversos , Neoplasias/etiología , Adulto , Anciano , Estudios de Cohortes , Femenino , Finlandia/epidemiología , Humanos , Incidencia , Masculino , Persona de Mediana Edad , Neoplasias/epidemiología
12.
J Arthroplasty ; 12(4): 397-402, 1997 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-9195315

RESUMEN

The causes of death in 1,018 patients operated on for primary osteoarthrosis with cemented total hip arthroplasty (THA) were compared with those of age- and sex-matched orthopaedic control patients and those of the general population in Finland. The mean follow-up period was 12 years for the THA patients and 11 years for the control patients. During the first 4 years after surgery, the mortality of the THA patients from circulatory diseases was significantly increased compared with that of the orthopaedic control patients; the number of deaths in patients with THA was 34 compared with 17 for orthopaedic control patients, the relative risk being 2.00 (95% confidence interval, 1.13-3.54). During the 10-year period after the surgery, the relative risk of death of the THA patients compared with the orthopaedic control patients was 1.50 for death from circulatory diseases (95% confidence intervals, 1.11-2.00), 0.42 for accidental death (95% confidence interval, 0.55-1.08), 0.74 for death from cancer, and 0.77 for death from other causes. The observed numbers of deaths from circulatory diseases or by accidents for patients with THA during a postoperative time frame of 5 to 23 years did not differ from the numbers expected for an age- and sex-matched subgroup of the Finnish population. The number of deaths from cancer was less than expected (P = .046).


Asunto(s)
Causas de Muerte , Prótesis de Cadera/mortalidad , Osteoartritis/cirugía , Accidentes/mortalidad , Enfermedades Cardiovasculares/mortalidad , Trastornos Cerebrovasculares/mortalidad , Femenino , Finlandia/epidemiología , Estudios de Seguimiento , Prótesis de Cadera/métodos , Humanos , Masculino , Persona de Mediana Edad , Neoplasias/mortalidad , Estudios Retrospectivos , Factores de Riesgo , Tasa de Supervivencia
13.
Int J Technol Assess Health Care ; 13(4): 575-88, 1997.
Artículo en Inglés | MEDLINE | ID: mdl-9489250

RESUMEN

The extensive benefits of the total hip (THA) and knee (TKA) replacements are well documented, but surprisingly little is known about their economics. We assessed costs, cost-effectiveness (C/E), and patient-related C/E variances in THA and TKA from data on 276 THA and 176 TKA patients. Patients with primary arthrosis, primary operation, and total joint replacement were recruited from seven hospitals between March 1991 and June 1992. Their use of health and other welfare services together with health-related quality of life (HRQoL) were measured before the surgery and at 6, 12, and 24 months postoperatively. HRQoL was assessed by the 15D, a 15-dimensional HRQoL instrument, and the Nottingham Health Profile. Costs were assessed from questionnaire responses, the Finnish Hospital Discharge Register, and Finnish Arthroplasty Register. Total hospital costs per patient were 45,000 FIM (US $10,500) for THA and 49,600 FIM (US $11,500) for TKA. Prosthesis costs comprised 21% of these costs in THA and 24% in TKA. On average, hip patients gained more in terms of HRQoL, and the operations were more cost-effective. The C/E ratio for younger (< or = 60 years) knee patients did not differ from those in all age groups of hip patients, whereas TKAs in those over 60 years had a worse C/E ratio compared with all other patient subgroups. It was concluded that allocation efficiency can be improved by considering not only the intervention but also patient characteristics such as age. Indeed, the C/E ratio varied more across age groups of knee patients than between average THA and TKA patients.


Asunto(s)
Artroplastia de Reemplazo de Cadera/economía , Artroplastia de Reemplazo de Rodilla/economía , Costos de la Atención en Salud , Adulto , Anciano , Anciano de 80 o más Años , Artroplastia de Reemplazo de Cadera/rehabilitación , Artroplastia de Reemplazo de Rodilla/rehabilitación , Análisis Costo-Beneficio , Femenino , Finlandia , Estudios de Seguimiento , Costos de Hospital , Humanos , Masculino , Persona de Mediana Edad , Evaluación de Resultado en la Atención de Salud , Análisis de Supervivencia
14.
Clin Orthop Relat Res ; (329 Suppl): S280-9, 1996 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-8769342

RESUMEN

The incidence of cancer after metal on metal total hip arthroplasty (McKee-Farrar) and polyethylene on metal total hip arthroplasty (Brunswik, Lubinus) was compared with that of the general population in Finland. The mean followup time for the patients who had metal on metal total hip arthroplasty was 15.7 (9092 person years) and for the patients who had polyethylene on metal total hip arthroplasty it was 12.5 years (19,846 person years). One hundred thirteen malignant cancers were observed in patients who had metal on metal total hip arthroplasty and 212 were observed in patients who had polyethylene on metal total hip arthroplasty. The standardized incidence ratio for all cancers of the metal on metal arthroplasty group was 0.95 (95% confidence limits 0.79-1.13) and that of the polyethylene on metal arthroplasty group was 0.76 (95% confidence limits 0.68-0.86). The risk of total cancer in the patients who had metal on metal total hip arthroplasty was 1.23-fold compared with that of the patients who had polyethylene on metal total hip arthroplasty. Both groups had significantly less lung cancer than the general population: the leukemia incidence in the patients who had metal on metal total hip arthroplasty was slightly increased (observed to experienced 7/3.03, standardized incidence ratio 0.61; 95% confidence limits 0.17-1.56). The leukemia rate of the patients who had metal on metal total hip arthroplasty was 3.77-fold compared with that of the patients who had polyethylene on metal total hip arthroplasty, but this difference was not statistically significant. No sarcomas were observed at the site of the prosthesis. The incidence of the other forms of cancers did not differ significantly from those in the general population. The observed variation in the incidence of different cancers among patients who had total hip arthroplasty compared with the general population suggests that factors other than total hip arthroplasty play a major role in the origin of cancer.


Asunto(s)
Prótesis de Cadera/efectos adversos , Metales/toxicidad , Neoplasias/inducido químicamente , Polietilenos/toxicidad , Anciano , Carcinógenos , Intervalos de Confianza , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Riesgo
15.
Qual Life Res ; 5(1): 56-64, 1996 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-8901367

RESUMEN

The impact of hip (THA) and knee arthroplasty (TKA) on patients' health-related quality of life (HRQOL), physical ability and functioning was assessed in a two year follow-up study of 276 hip and 176 knee patients. The eligibility criteria were a diagnosis of primary arthrosis, a primary operation, and total joint arthroplasty. Patients were interviewed by questionnaire prior to the operation and 6, 12 and 24 months after the surgery. Subjective health outcomes were assessed with the Nottingham Health Profile and the 15D, a fifteen dimensional HRQOL measure. Patients' physical ability was assessed using measures of activities of daily living, and of physical mobility. Patient related outcome variations were analyzed by regression models. Major improvements were observed for pain, sleep and physical mobility. On average, in most of the quality of life dimensions the patients attained a similar quality of life as the comparable general population and only 4.7% of hip and 9.7% of knee patients had a worse HRQOL score at all three post-operative measurements than at baseline. Naturally, those with the poorest HRQOL pre-operatively gained most from the operation. High age did not lessen HRQOL gains from THA, but in TKA the oldest patients gained least in terms of 15D scores. Hip, but not knee patients with a long education tended to have greater improvements in quality of life and functional ability.


Asunto(s)
Prótesis de Cadera/rehabilitación , Prótesis de la Rodilla/rehabilitación , Calidad de Vida , Actividades Cotidianas , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Finlandia , Prótesis de Cadera/psicología , Humanos , Prótesis de la Rodilla/psicología , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Análisis de Regresión , Resultado del Tratamiento
16.
J Arthroplasty ; 10(2): 169-75, 1995 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-7798097

RESUMEN

The impact of hip and knee arthroplasty based on the patients' own evaluations of their health, quality of life, and physical ability was assessed using a cross-sectional study design. The eligibility criteria were a diagnosis of primary arthrosis, primary operation, and total joint arthroplasty. Preoperative hip and knee patient groups were compared with similar groups who underwent arthroplasty 2 or 5 years previously. Subjective health outcome was assessed with the Nottingham health profile and a 15-dimensional, health-related quality of life measure. Patients' physical ability was assessed using a measure of activities of daily living. Major improvements were observed for pain, sleep, range of motion, and physical ability. However, after surgery, patients were less healthy than the general population of the same age. The health status of patients operated on 2 or 5 years ago was similar, suggesting that health gains persist for several years.


Asunto(s)
Estado de Salud , Prótesis de Cadera/psicología , Prótesis de la Rodilla/psicología , Calidad de Vida , Actividades Cotidianas , Anciano , Estudios Transversales , Femenino , Indicadores de Salud , Humanos , Masculino , Persona de Mediana Edad , Periodo Posoperatorio , Factores de Tiempo , Resultado del Tratamiento
17.
J Bone Joint Surg Am ; 76(3): 335-40, 1994 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-8126038

RESUMEN

The accuracy of ultrasonography and arthrography in the prediction of lesions of the rotator cuff was evaluated and compared with the operative findings in a retrospective study of forty-nine patients (forty-nine shoulders). In the detection of full-thickness (stage-III) tears of the rotator cuff, ultrasonography had an over-all sensitivity of 74 per cent, a specificity of 95 per cent, an accuracy of 84 per cent, a predictive value of a positive test of 95 per cent, and a predictive value of a negative test of 75 per cent. In contrast, arthrography demonstrated a sensitivity of 93 per cent, a specificity of 95 per cent, an accuracy of 94 per cent, a predictive value of a positive test of 96 per cent, and a predictive value of a negative test of 91 per cent. Ultrasonography could not reliably differentiate between partial (stage-II) and full-thickness (stage-III) tears. Lesions of the long head of the biceps brachii tendon were recorded by ultrasonography for twenty-two patients (45 per cent) and by arthrography for eleven patients (22 per cent). The ultrasonographic finding of fluid in the sheath of this tendon is not a reliable sign of a lesion in the tendon.


Asunto(s)
Lesiones del Manguito de los Rotadores , Traumatismos de los Tendones/diagnóstico por imagen , Adulto , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Valor Predictivo de las Pruebas , Radiografía , Reproducibilidad de los Resultados , Estudios Retrospectivos , Manguito de los Rotadores/diagnóstico por imagen , Sensibilidad y Especificidad , Articulación del Hombro/diagnóstico por imagen , Traumatismos de los Tendones/cirugía , Ultrasonografía
18.
Acta Orthop Scand ; 65(1): 9-11, 1994 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-8154292

RESUMEN

The long-term survival of 1018 total hip arthroplasty (THA) patients (237 McKee-Farrar, 449 Brunswik and 332 Lubinus patients) operated on for primary arthrosis was compared with pair-matched controls (i.e., patients operated on for other orthopedic indications) and with a normal population. The 10-year survival after surgery for the McKee-Farrar patients was 85 percent, for the Brunswik patients 82 percent, for the Lubinus patients 82 percent and for the orthopedic control patients 84 percent, respectively. The 10-year survival after 65 years of age for the THA patients was 78 percent and for the normal population 73 percent. The long-term life expectancy of our patients with a cemented THA was equal to that of our orthopedic control group and better than the life expectancy of the Finnish population.


Asunto(s)
Prótesis de Cadera , Esperanza de Vida , Osteoartritis de la Cadera/mortalidad , Factores de Edad , Anciano , Estudios de Casos y Controles , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Osteoartritis de la Cadera/cirugía , Factores Sexuales , Tasa de Supervivencia , Factores de Tiempo
19.
J Arthroplasty ; 8(6): 581-4, 1993 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-8301274

RESUMEN

Radiographic signs of loosening were assessed, and their sequential appearance recorded, in a retrospective analysis of 20 loosened, threaded acetabular cups. There was radiographic evidence of loosening in 19 (95%) cups. In decreasing order of frequency, the radiographic manifestations included bone resorption between the threads in 19 (95%) cups, increased bone density above the cup in 15 (75%), continuous lucency around the cup in 14 (70%), axial migration in 9 (45%), and rotation in 6 (30%). The order of appearance of these radiographic manifestations was the same as the order of frequency of occurrence of the alterations. In the one patient with no radiographically detectable signs of loosening, the cup did not move freely but was easily detached during surgery. Early radiographic diagnosis of loosening requires accurate positioning of the patient in order for the radiographs to reveal bone resorption between the threads of the cup.


Asunto(s)
Articulación de la Cadera/diagnóstico por imagen , Prótesis de Cadera , Acetábulo/diagnóstico por imagen , Adulto , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Diseño de Prótesis , Falla de Prótesis , Radiografía , Estudios Retrospectivos
20.
Clin Orthop Relat Res ; (297): 71-81, 1993 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-8242955

RESUMEN

A new straight cementless stem was used for replacement of 67 dislocated or severely dysplastic hips. There were 45 hips with complete dislocation, 27 of which were cases after Schanz osteotomy. Technical solutions for various deformities are presented here. The acetabular component was placed at the level of the original cotyloid cavity or some lower position. In hips after total dislocation a metaphyseal shortening osteotomy was combined with distal advancement of the greater trochanter with intact attachment of the abductor muscles. This method was appropriate also for the femora, where high-seated Schanz osteotomy was previously performed. If the diaphysis was too narrow for the stem, it was split about 10 cm both anteriorly and posteriorly. In cases with unilateral total dislocation where Schanz osteotomy had been seated low, metaphyseal segmental shortening with angular correction was performed and the stem was used as an intramedullary nail. Special attention was paid to achieve sufficient abduction strength to balance the pelvis and abolish Trendelenburg limp and to restore leg length. The clinical and radiographic results of the consecutive series were assessed three to five years after the arthroplasty. Pain relief and the functional results including improvement of gait were generally good, primary complications were few, but the loosening and revision rate of the smooth-threaded acetabular component was unacceptably high. There were no problems with the press-fit cups. In general the outcomes were good even when reoperation was required.


Asunto(s)
Luxación Congénita de la Cadera/cirugía , Prótesis de Cadera , Adulto , Anciano , Artroplastia/métodos , Femenino , Fémur/diagnóstico por imagen , Fémur/cirugía , Estudios de Seguimiento , Luxación Congénita de la Cadera/complicaciones , Humanos , Deformidades Adquiridas de la Articulación/cirugía , Diferencia de Longitud de las Piernas/etiología , Masculino , Persona de Mediana Edad , Diseño de Prótesis , Radiografía
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA