RESUMEN
We report a case of a 39-year-old, HIV-negative, post renal transplant patient who developed mucocutaneous Kaposi's sarcoma with lung parenchymal involvement and concurrently culture proven pulmonary tuberculosis. To the best of our knowledge, this is the first case report of this combination, which presented with cavitating lung nodules and responded well to withdrawal of immunosuppressive drugs beside antituberculous treatment.
Asunto(s)
Trasplante de Riñón , Neoplasias Pulmonares/complicaciones , Neoplasias Pulmonares/diagnóstico , Sarcoma de Kaposi/complicaciones , Sarcoma de Kaposi/diagnóstico , Tuberculosis Pulmonar/complicaciones , Tuberculosis Pulmonar/diagnóstico , Adulto , Antituberculosos/uso terapéutico , Quimioterapia Combinada , Humanos , Inmunosupresores/administración & dosificación , Inmunosupresores/efectos adversos , Neoplasias Pulmonares/inducido químicamente , Masculino , Radiografía Torácica , Sarcoma de Kaposi/inducido químicamente , Tomografía Computarizada por Rayos X , Tuberculosis Pulmonar/tratamiento farmacológicoRESUMEN
UNLABELLED: Pyostomatitis vegetans is an oral eruption, characterized by small pustules, ulcers and erythematous vegetations of the labial and buccal mucosae as well as labial-attached gingivae. Its importance lies in its high correlation with inflammatory bowel disease. It is commonly associated with skin and inflammatory bowel disease and is rare in children. We here report a sister and brother with onset of the disease at the age of 5 and 7 years, respectively. It is the first report of familial pyostomatitis vegetans occurring in the youngest patients hitherto reported. CONCLUSION: The observation of two sibs with pyostomatitis, vegetans pyoderma gangrenosum and inflammatory bowel disease suggest a hereditary disposition to this rare triad.
Asunto(s)
Enfermedades Inflamatorias del Intestino/complicaciones , Piodermia Gangrenosa/complicaciones , Estomatitis/complicaciones , Adolescente , Edad de Inicio , Niño , Preescolar , Femenino , Humanos , MasculinoRESUMEN
Acanthoma fissuratum secondary to the use of spectacles is a rare clinical finding associated with an ill-fitting frame. An interesting case is presented to highlight such a problem. Surgical excision of such lesions is recommended with advice to the patient regarding the suitable fitting of spectacles.
Asunto(s)
Oído Externo/patología , Pólipos/patología , Neoplasias Cutáneas/patología , Adulto , Oído Externo/cirugía , Anteojos , Humanos , Masculino , Pólipos/cirugía , Neoplasias Cutáneas/cirugíaRESUMEN
The infantile cholangiopathies are a group of conditions associated with neonatal jaundice, which include extrahepatic biliary atresia, paucity of intra-hepatic bile ducts and disorders associated with persistence of fetal biliary structures, the so-called ductal plate malformations. Although previously regarded as distinct entities, it has recently been suggested that they may represent parts of a disease spectrum in which the principal process is one of bile duct destruction, the morphological manifestations in individual cases being influenced by the stage of intra-uterine development at which such injury occurs and by the site within the biliary system at which there is maximum damage. To further examine this concept, we have studied liver biopsy specimens from 37 neonates with extrahepatic biliary atresia, with particular reference to abnormalities of the intrahepatic bile ducts. Paucity of intrahepatic ducts, defined as a bile duct: portal tract ratio of less than 0.9, was identified in six cases (16.2%). In eight cases (21.6%) we found concentric tubular ductal structures similar to those observed in ductal plate malformations. In one case, both abnormalities could be demonstrated. Our findings support the concept that there is overlap between the various types of infantile cholangiopathy.